HUMAN UROTHELIAL CELLS
Differences in the epigenetic regulation of MT-3 gene expression between parental and Cd+2 or As+3 transformed human urothelial cells
... of human urothelial cells that was immortalized using the SV40 large T-antigen ...UROtsa cells retain a normal cytogenetic profile, grow as a contact inhibited monolayer, and are not ...
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Heparin binding EGF like growth factor is an autocrine growth factor for human urothelial cells and is synthesized by epithelial and smooth muscle cells in the human bladder
... the human bladder epithelium (urothelium), however a cog- nate HER1 ligand that can act as a growth factor for normal human urothelial cells (HUC) has not been ...of human urothelium as ...
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Ketamine-Induced Apoptosis in Normal Human Urothelial Cells : A Direct, N-Methyl-d-Aspartate Receptor-Independent Pathway Characterized by Mitochondrial Stress
... (nonimmortalized) human urothelial cells were unresponsive to NMDAR agonists or antagonists, and no expression of NMDAR transcript was ...to urothelial cells by activating the intrinsic ...
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β-adrenergic receptor activation in immortalized human urothelial cells stimulates inflammatory responses by PKA-independent mechanisms
... in urothelial cells that leads to selective induction of protein products associated with inflammatory ...described human urothelial cell line expressing functional β -ARs increases production ...
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ZIP8 expression in human proximal tubule cells, human urothelial cells transformed by Cd+2 and As+3 and in specimens of normal human urothelium and urothelial cancer
... HPT cells. These cells were chosen for analysis since the in situ expression of ZIP8 has previously been shown for this cell type along with an association of ZIP8 with Cd-induced damage to the proximal ...
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Specificity of the Metallothionein-1 Response by Cadmium-Exposed Human Urothelial Cells
... Preliminary investigation into the effect of cadmium exposure on zinc homeostasis in normal urothelial cells revealed an upregulation of the zinc transporter-1 SLC30A1 gene transcript in[r] ...
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Immortalisation of Normal Human Urothelial Cells Compromises Differentiation Capacity
... epithelial cells [29,30], were immortalised by hTERT over-expression ...with urothelial senescence in culture and is recognised as an essential block to neoplastic transformation ...
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Review Article Tobacco smoke and bladder cancer: the current research status and the future challenges
... mal human urothelial cells via the NF-κB pathway ...smoke-induced urothelial cell car- cinoma ...a human bladder can- cer cell line ...
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Cortex Moutan Inhibits Bladder Cancer Cell Proliferation and Expression of Angiogenic Factors
... on human cancer cell lines encompassing such common malignancies as breast ductal carcinoma, colon cancer, hepatocellular carcinoma, gastric cancer, and esophageal cancer [18]-[22] ...cancer cells, which is ...
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The impact of detergents on the tissue decellularization process: a ToF SIMS study
... ToF-SIMS analysis was used to identify differences in the composition of urinary bladder matrix, a representative biologic scaffold, exposed to detergents; surface molecular functionality was correlated with in vitro ...
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Urothelial cells may indicate underlying bacteriuria in pregnancy at term: a comparative study
... clue cells, demonstrate bladder immune response to cellular invasion by ...differentiated urothelial cells including both the bladder and urethra, we were unable to ascertain the precise origin of ...
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Case Report Müllerianosis and endosalpingiosis of the urinary bladder: report of two cases with review of the literature
... surface urothelial epithelium was with- out atypia, and no connection between the sur- face urothelial mucosa and dilated tubular glands was noted (Figure ...cuboidal cells containing small round ...
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Original Article Targeting MACC1 by RNA interference inhibits proliferation and invasion of bladder urothelial carcinoma in T24 cells
... SV-HUC-1 cells originated from human normal ...BIU87 cells derived from human urothelial cell ...All cells were cultured in RPMI-1640 media (Life Technologies, Rockville, MD, ...
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Impact of Hepatitis C Virus (HCV) infection on biomolecular markers influencing the pathogenesis of bladder cancer
... Each specimen of bladder biopsy from malignant tissues and normal urothelium was divided into two parts: a small fresh part was frozen for PCR and the large portion was fixed in 10% buffered formalin. The paraffin blocks ...
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Overexpression of high mobility group box 1 contributes to progressive clinicopathological features and poor prognosis of human bladder urothelial carcinoma
... sion of HMGB1, in both mRNA and protein levels, in BUC and paired normal bladder tissues by qRT-PCR and Western blot, respectively. The results revealed that HMGB1 was overexpressed in BUC tissue compared with the paired ...
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DDR2 overexpression in urothelial carcinoma indicates an unfavorable prognosis: a large cohort study
... Figure 6: DDR2 expression is associated with tumorigenic potential by enhancing proliferative, migratory, and invasive ability of tumor cells. (A) Endogenous DDR2 transcript expression are determined by ...
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Histologic variants of urothelial bladder cancer and nonurothelial histology in bladder cancer
... Increasing attention in recent years, along with more spe- cific and sensitive markers, has led to heightened recogni- tion of the divergent differentiation often present in urothe- lial cancer. The most commonly ...
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Micronucleus assay in urothelial cells of patients with abnormal colposcopy and histopathological correlation
... This is to certify that this dissertation work titled “ MICRONUCLEUS ASSAY IN UROTHELIAL CELLS OF PATIENTS WITH ABNORMAL COLPOSCOPY AND HISTOPATHOLOGICAL CORRELATION” of the candidate Dr.T.M.VINCY with ...
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Phosphatidylinositol 3'-kinase, mTOR, and Glycogen synthase kinase-3β mediated regulation of p21 in human urothelial carcinoma cells
... in human urothelial cell lines that stimulation of the PI3-kinase/ AKT pathway leads to an increase in p21 ...in human and rat bladder cancer cell lines [37-39] have shown that induction of p21 ...
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Circulating tumour cells in patients with urothelial tumours: Enrichment and in vitro culture
... In total, we reviewed 8 patients diagnosed with 3 types of urothelial tumors: 3 with prostate cancer, 3 with urinary bladder cancer and 2 with kidney cancer (Table 1). The final diagnoses were based on the ...
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