HUVEC Cells
Radio-protective effect and mechanism of 4-Acetamido-2,2,6,6- tetramethylpiperidin-1-oxyl in HUVEC cells
... It is known that GSH plays an important role in the antioxidation of reactive oxygen species (ROS) and free radicals [44 – 46]. It is a potent free radical and reactive oxygen species scavenger [47]. Irreversible cell ...
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Enhancement of mitochondrial biogenesis with polyphenols: combined effects of resveratrol and equol in human endothelial cells
... The qRT-PCR technique was used to determine the effect of resveratrol, equol and of the mixture of the two com- pounds (resveratrol + equol) (10 μM for 24 h) on mRNA expression of mitochondrial biogenesis factors such as ...
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Rapid production of human liver scaffolds for functional tissue engineering by high shear stress oscillation decellularization
... LX2 cells, respectively), human umbilical vein endothelial cells (HUVEC), as well as primary human hepatocytes and hepatic stellate ...liver cells grown in ALTCs exhibited markedly different ...
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<p>A carbohydrate mimetic peptide modified size-shrinkable micelle nanocluster for anti-tumor targeting and penetrating drug delivery</p>
... the pH-sensitive and cross-linked structure through the electrostatic adsorption, with micelles aggregated inside the framework. The particle size was 112.27±6.81 nm and the morphology examined by TEM displayed the ...
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Renal cell carcinoma alters endothelial receptor expression responsible for leukocyte adhesion
... of HUVEC with RCC cell ...co-culturing HUVEC with Caki-1 ...with HUVEC, was only detectable with ...with HUVEC-Caki-1 co-culture supernatant, indicating that a soluble factor released by ...
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A novel microfluidic model can mimic organ-specific metastasis of circulating tumor cells
... endothelial cells (HUVEC) were seeded in the microchannels, pre-coated with Cultrex Basement Membrane Extracts (BME), a substitution of extracellular matrix, via the cell reservoir at ...Primary ...
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Plasma irisin is elevated in type 2 diabetes and is associated with increased E-selectin levels
... lized HUVEC cells as a model of the endothelium and observed that exposure to irisin, at concentrations com- parable to those in many of the obese T2DM patients of this study, induced a significant increase ...
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Intracellular proteolysis of kininogen by malaria parasites promotes release of active kinins
... Results: In the present work, it was demonstrated by mass spectrometry analysis that Plasmodium parasites (Plasmodium chabaudi and Plasmodium falciparum) internalize and process plasma kininogen, thereby releasing ...
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Chemically modified, non-anticoagulant heparin derivatives are potent galectin-3 binding inhibitors and inhibit circulating galectin-3-promoted metastasis
... No detectable cytotoxic effect of the heparin derivatives on human cancer ACA19+ and SW620 or endothelial HUVEC cells* Compound LDH LDH LDH 100ug/ml SW620 cells ACA19+ cells HUVEC cells [r] ...
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Zolav<sup>®</sup>: a new antibiotic for the treatment of acne
... inhaled. HUVEC cells were used here as a model cell line to gauge the cytotoxicity of skin cells, with the results showing no cell death observed in HUVEC and lung cells at the high- ...
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Original Article Lung cancer-targeting treatment of iRGD-LP-DOX/Rg3 through integrin receptor-medicated endocytosis
... and HUVEC (human umbilical vein endothelial cells) cell ...and HUVEC cells and confocal microscopy was used to qualitatively observe the uptake of RGD-LP-DOX/Rg3 by A549 and HUVEC ...
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Monocarboxylate transporter 1 and monocarboxylate transporter 4 in cancer-endothelial co-culturing microenvironments promote proliferation, migration, and invasion of renal cancer cells
... cancer cells resistant to apoptosis and helps stabilize the mitochondrial outer membrane (OMM) by promoting the attachment of mitochondrial hexoki- nase (mtHK) to the VDAC channel complex ...
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Interaction among activated lymphocytes and mesenchymal cells through podoplanin is critical for a high IL 17 secretion
... inflammation, the potential contribution of monocytes in this loop was investigated. To study their involvement in our co-culture system, monocytes were removed by ad- herence. As IL-1β is mainly produced by monocytes in ...
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New CXCR1/CXCR2 inhibitors represent an effective treatment for kidney or head and neck cancers sensitive or refractory to reference treatments
... naive cells and on sunitinib [32] and cisplatin-resistant cells to compare the C29 ...RCC cells as efficiently as sunitinib (786, Figure 4A-E, Figure ...786-O cells (786R, Figure 4B-F, Figure ...
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Original Article The antitumor effect of the novel cancer-specific adenovirus Ad-VEGFR on bladder cancer in vitro and in vivo
... significantly and negatively correlated to the progression and invasion of cancer [12, 13]. Hence, it is a useful strategy for BC-treatment by interfering with the expression VEGFR. Gene therapy has the advantage of ...
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Indoleamine 2,3-Dioxygenase Mediates Cell Type-Specific Anti-Measles Virus Activity of Gamma Interferon
... dendritic cells, in mice with IDO-expressing tumors leading to an escape from cytotoxic responses, and after the expression of IDO in trophoblasts as a mechanism preventing the immune response against fetal tissue ...
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Cryopreservation of human vascular umbilical cord cells under good manufacturing practice conditions for future cell banks
... positive HUVEC was considerable higher (passage 3: ...expressing cells (100 %) in the endothelial lumen of cord vessels, quantified by immunostaining of native human umbilical cord cross sections ...
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Macrophage derived interleukin 1beta promotes human breast cancer cell migration and lymphatic adhesion in vitro
... tumour cells were counted using a fluorescence microscope ...of cells adhered relative to ...endothelial cells and cytokine were responding appropri- ...
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Plant proteolytic enzyme papain abrogates angiogenic activation of human umbilical vein endothelial cells (HUVEC) in vitro
... We then investigated the phosphorylation status of AKT1, ERK1/2, MEK1/2, p38-MAPK and SAPK/JNK after pre-treatment with papain and found a modulation of phosphorylation levels of AKT1, MEK1/2, p38-MAPK and SAPK/JNK ...
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Modification of composition of a nanoemulsion with different cholesteryl ester molecular species: Effects on stability, peroxidation, and cell uptake
... The cells were washed three times with phosphate-buffered saline. The cells were harvested from the culture dish by treatment with a trypsin solution ...
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