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Hyaluronic Acid

Hyaluronic Acid / Viscosupplemenation

Hyaluronic Acid / Viscosupplemenation

... Intra-articular Hyaluronic Acid Injections are Safe and Effective in Patients with Knee Osteoarthritis: Systematic Review and Meta-analysis of Randomized, Saline-controlled ...

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Effects of hyaluronic acid combined with anti inflammatory drugs compared with hyaluronic acid alone, in clinical trials and experiments in osteoarthritis: a systematic review and meta analysis

Effects of hyaluronic acid combined with anti inflammatory drugs compared with hyaluronic acid alone, in clinical trials and experiments in osteoarthritis: a systematic review and meta analysis

... HA: Hyaluronic acid; IA: Intra-articular injection; ITT: Intent-to-treat; kDa: Kilodaltons; KE: Ketorolac; MDa: Megadaltons; MPA: Methylprednisolone; MW: Molecular weight; NSAIDs: Non-steroidal ...

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Crosslinking of hyaluronic acid and human like collagen with divinyl sulfone

Crosslinking of hyaluronic acid and human like collagen with divinyl sulfone

... Hyaluronic acid/human-like collagen hydrogel was prepared by the method as previous description [11]. Briefly, HA and HLC (total amount 0.1 g), in a mass ratio of 4:1, were dissolved into 4 mL 0.2 M NaOH ...

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Synthesis and Degradation of Hyaluronic Acid in the Cultured Fibroblasts of Marfan's Disease

Synthesis and Degradation of Hyaluronic Acid in the Cultured Fibroblasts of Marfan's Disease

... Marfan-derived fibroblasts incorporated [ 14 C]acetate or [ 14 C]glucosamine into GAG to a level 4-6 times greater than control fibroblasts. Sugar analyses, electrophoretic mobility, and enzyme susceptibility studies ...

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Standardized in vitro analysis of the degradability of hyaluronic acid fillers by hyaluronidase

Standardized in vitro analysis of the degradability of hyaluronic acid fillers by hyaluronidase

... Hyaluronic acid (hyaluronan, HA) is a non-sulfated gly- cosaminoglycan (GAG) and an essential part of the skin’s extracellular matrix (ECM) [1, 2]. A decrease in the skin’s HA content is considered as main ...

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Phytosome-hyaluronic acid systems for ocular delivery of L-carnosine

Phytosome-hyaluronic acid systems for ocular delivery of L-carnosine

... Abstract: This study reports on L-carnosine phytosomes as an alternative for the prodrug N-acetyl-L-carnosine as a novel delivery system to the lens. L-carnosine was loaded into lipid- based phytosomes and ...

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Engineered Fibrous Hyaluronic Acid Hydrogels for Cartilage Repair

Engineered Fibrous Hyaluronic Acid Hydrogels for Cartilage Repair

... Cartilage-related pain, resulting from osteoarthritis or acute trauma, is the leading cause of disability among adults, and the number of people affected is predicted to double by the year 2020 [1-3]. Chapters 1 and 3 ...

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Recent advances in hyaluronic acid based therapy for osteoarthritis

Recent advances in hyaluronic acid based therapy for osteoarthritis

... Human clinical studies involving hyaluronic acid Improved hydrogels are continuously being made that seek to maximize the effect of treatment. One such is called Gel-One, which is composed of a product ...

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Hyaluronic acid gel fillers in the management of facial aging

Hyaluronic acid gel fillers in the management of facial aging

... stabilized hyaluronic acid” (NASHA) and produced from cultures of Streptococcus equi via a proprietary process crosslinked with 1,4-butanediol diglycidyl ether (BDDE) giving a fi nal concentration of 20 ...

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The effects of hyaluronic acid on the morphological physiological differentiation of Lactobacillus

The effects of hyaluronic acid on the morphological physiological differentiation of Lactobacillus

... groups. Hyaluronic acid increased the bacteriocin excretion that will be a promising factor in medicine, food and ...and hyaluronic acid on the market, especially the exits of the probiotic ...

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Microbial production of hyaluronic acid: current state, challenges, and perspectives

Microbial production of hyaluronic acid: current state, challenges, and perspectives

... Hyaluronic acid (HA) is composed of disaccharide repeats of D-glucuronic acid (GlcUA) and N-acetylglu- cosamine (GlcNAc) joined alternately by b-1, 3 and b-1, 4 glycosidic bonds (Figure ...

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Inhibition of antithrombin by hyaluronic acid may be involved in the pathogenesis of rheumatoid arthritis

Inhibition of antithrombin by hyaluronic acid may be involved in the pathogenesis of rheumatoid arthritis

... Thrombin is a key factor in the stimulation of fibrin deposition, angiogenesis, proinflammatory processes, and proliferation of fibroblast-like cells. Abnormalities in these processes are primary features of rheumatoid ...

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In vitro and ex vivo effect of hyaluronic acid on erythrocyte flow properties

In vitro and ex vivo effect of hyaluronic acid on erythrocyte flow properties

... Figure 1 Rigidity Index (RI) of erythrocytes incubated in vitro with variable HA concentrations, and reversibility of HA effect. In vitro effect of several.hyaluronic acid (HA) concentrations on rigidity index ...

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The preparation and some properties of hyaluronic acid from human umbilical cord

The preparation and some properties of hyaluronic acid from human umbilical cord

... Hyaluronic acid has now been known for ten years and in this period the literature about it has become both extensive and inconsistentL A number of sub- stances with varying properties h[r] ...

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Cytokine regulation of human lung fibroblast hyaluronan (hyaluronic acid) production  Evidence for cytokine regulated hyaluronan (hyaluronic acid) degradation and human lung fibroblast derived hyaluronidase

Cytokine regulation of human lung fibroblast hyaluronan (hyaluronic acid) production Evidence for cytokine regulated hyaluronan (hyaluronic acid) degradation and human lung fibroblast derived hyaluronidase

... We characterized the mechanisms by which recombinant (r) tumor necrosis factor (TNF), IFN-gamma, and IL-1, alone and in combination, regulate human lung fibroblast hyaluronic acid (HA) production. Each ...

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A placebo-controlled study comparing the efficacy of intra-articular injections of hyaluronic acid and a novel hyaluronic acid-platelet-rich plasma conjugate in a canine model of osteoarthritis

A placebo-controlled study comparing the efficacy of intra-articular injections of hyaluronic acid and a novel hyaluronic acid-platelet-rich plasma conjugate in a canine model of osteoarthritis

... The most important goal of treatments for osteoarth- ritis is to alleviate pain. Pain management allows the patient to regain strength and function and maintain the movability of the affected limb [5]. Other goals of ...

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Proteome analysis of the hyaluronic acid-producing bacterium, Streptococcus zooepidemicus

Proteome analysis of the hyaluronic acid-producing bacterium, Streptococcus zooepidemicus

... Lancefield Group A and C streptococci produce the exopolysaccharide hyaluronic acid (HA). The HA capsule protects streptococci from phagocytosis [5-8] and may facilitate tissue adherence and invasion [5,9]. ...

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Dextranomer/Hyaluronic Acid for Pediatric Vesicoureteral Reflux: Systematic Review

Dextranomer/Hyaluronic Acid for Pediatric Vesicoureteral Reflux: Systematic Review

... We searched the Cochrane Controlled Trials Register and Medline, Embase, and Scopus electronic databases for studies published between January 1990 and December 2008 in any lan- guage. A deliberately wide date range was ...

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The use of hyaluronic acid based dressings to treat burns: A review

The use of hyaluronic acid based dressings to treat burns: A review

... polymers. Hyaluronic acid (HA) is involved in many steps of the wound healing process, such as infl ammation, granulation and ...these hyaluronic acid derivatives represent a valuable option ...

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Purification and biocompatibility of fermented hyaluronic acid for its applications to biomaterials

Purification and biocompatibility of fermented hyaluronic acid for its applications to biomaterials

... Removal of used adsorbents After HA purification, the used adsorbents needed to be removed by filtration to obtain the pure HA products. Even though all the acti- vated carbons were removed from the processed broth, ...

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