Hyperinsulinemic hypoglycemia
Severe Hyperinsulinemic Hypoglycemia in a Neonate: Response to Sirolimus Therapy
... Hyperinsulinemic hypoglycemia (HH) is one of the most common causes of persistent hypoglycemic episodes in ...severe hypoglycemia presented with extremely high serum insulin levels immediately after ...
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Octreotide therapy and restricted fetal growth: pregnancy in familial hyperinsulinemic hypoglycemia
... as hypoglycemia in itself, may pose a risk of fetal growth ...familial hyperinsulinemic hypoglycemia thus forms a medical ...familial hyperinsulinemic hypoglycemia, type ...severe ...
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Somatic deletion of the imprinted 11p15 region in sporadic persistent hyperinsulinemic hypoglycemia of infancy is specific of focal adenomatous hyperplasia and endorses partial pancreatectomy
... Patients. We studied only patients with neonatal PHHI onset (within 72 h of birth) who were diazoxide resistant. We administered 15 mg/ kg per d diazoxide in three doses/day for at least 5 d. Diazoxide effi- cacy was ...
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Original Article Persistent hyperinsulinemic hypoglycemia of infancy: constitutive activation of the mTOR pathway with associated exocrine-islet transdifferentiation and therapeutic implications
... Sprague-Dawlwey rats, if isolated and cultured in suspension, will lose amylase expression, and will convert to cells with a duct-like phenotype. Insulin-positive cells were also observed at the periphery of the ...
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Original Article Persistent hyperinsulinemic hypoglycemia of infancy: a clinical and pathological study of 19 cases in a single institution
... without any complications, and 6 cases had postoperative hyperglycemia and need a medication to control the blood glucose concentrations. Conclusion: Persistent hyperinsulinemic hypoglycemia of infancy ...
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Therapy for persistent hyperinsulinemic hypoglycemia of infancy Understanding the responsiveness of beta cells to diazoxide and somatostatin
... persistent hyperinsulinemic hypoglycemia of infancy (PHHI) arises as the result of mutations in the subunits that form the ATP-sensitive potassium (KATP) channel in pancreatic beta cells, leading to insulin ...
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A novel treatment of hyperinsulinemic hypoglycemia induced by insulin antibodies with alkali administration: a case report
... with hyperinsulinemic hypoglycemia possibly caused by IA induced by insulin analogs that had lower affinity and higher capacity against ...or hypoglycemia, because these antibodies usually have low ...
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Hyperinsulinemic hypoglycemia associated with insulin antibodies caused by exogenous insulin analog
... immunological hypoglycemia was an 11 cases report from China ...that hypoglycemia associated with insulin antibodies shall not be neglected in insulin-treated patients and if unexpectedly recurrent ...
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Neurologic Outcomes of 90 Neonates and Infants With Persistent Hyperinsulinemic Hypoglycemia
... that hypoglycemia was diag- nosed in 4 of our severely retarded patients very soon after birth, and they were treated in specialized neonatal or intensive care ...in hyperinsulinemic hypoglycemia to ...
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The Clinical Problem of Hyperinsulinemic Hypoglycemia and Resultant Infantile Spasms
... Hyperinsulinemic hypoglycemia (HH) is a cause of severe hypoglyce- mia in the newborn and infancy period and is associated with a high risk of neurologic handicap and ...
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Value of Selective Pancreatic Angiography in the Evaluation of Hyperinsulinemic Hypoglycemia in Infancy
... Value of Selective Pancreatic Angiography in the Evaluation of Hyperinsulinemic. Services[r] ...
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Monogenic hyperinsulinemic hypoglycemia: current insights into the pathogenesis and management
... continued hypoglycemia, octreotide during the day combined with continuous intragastric dextrose overnight is ef- fective at preventing octreotide tachyphylaxis and allows for stable glucose ...
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Clinical and molecular data from 61 Brazilian cases of Congenital Hyperinsulinemic Hypoglycemia
... of hypoglycemia associated with high levels of serum ammonia, and is also the major gene affected in cases in which no mutations are detected in genes ABCC8 and KCNJ11 ...
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Octreotide-Treated Diabetes Accompanied by Endogenous Hyperinsulinemic Hypoglycemia and Protein-Losing Gastroenteropathy
... of hypoglycemia attack were significantly high, and the values satisfied the criteria for hyperinsulinism defined by Service ...to hypoglycemia was not impaired; before and at the time of ...
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<p>Insulin Autoimmune Syndrome (Hirata Disease): A Comprehensive Review Fifty Years After Its First Description</p>
... immune-mediated hypoglycemia, which develops when a triggering factor (ie, a medication or a viral infection) acts on an underlying predisposing genetic ...Hirata, hypoglycemia, ...
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Ectopic insulin secreting neuroendocrine tumor of kidney with recurrent hypoglycemia: a diagnostic dilemma
... persisted hypoglycemia and re- quired continuous infusion of 10% Dextrose at the rate of 75 – 100 ml/hr in addition to 1-2 hourly ...during hypoglycemia showed a serum insulin of 134 ...symptomatic ...
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HNF4A related Fanconi syndrome in a Chinese patient: a case report and review of the literature
... Background: The p.R63W mutation in hepatocyte nuclear factor-4 alpha ( HNF4A ) leads to a heterogeneous group of disorders with various clinical presentations. Recently, patients with congenital hyperinsulinism and ...
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Is hypoglycemia fear independently associated with health-related quality of life?
... of hypoglycemia was assessed using the Hypoglycemia Fear Survey ...of hypoglycemia symptoms; Model 2 included both hypoglycemia symptoms and HFS ...1: hypoglycemia symptoms alone were ...
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Hypoglycemia: a review of definitions used in clinical trials evaluating antihyperglycemic drugs for diabetes
... Severe hypoglycemia is an important safety signal in the treatment of diabetes; almost half of the trials that reported the definition of severe hypoglycemia used BG/ PG values in addition to the ...
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1-s2.0-S1056872717312266-main.pdf
... induce hypoglycemia (chronic pancreatitis, pancreatic adenoma, pituitary adenoma, cystic fibrosis, hypopituitarism and adrenal ...second hypoglycemia hospitalization was ...
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