Hypertrophic scar
Microplasma radiofrequency technology combined with triamcinolone improved the therapeutic effect on Chinese patients with hypertrophic scar and reduced the risk of tissue atrophy
... Vancouver Scar Scale scores before the therapy between any groups ...Vancouver Scar Scale scores after the therapy were significantly lower than those before the therapy in all groups ...Vancouver ...
5
Effect of Topical Phytosterol Fraction of Chenopodium murale on Induced Hypertrophic Scar in Rabbits
... induced hypertrophic scar tissue represents severe inflammation and high number of polymorph nuclear cells, also dermis cellularity increases, fibroblasts were increased and arranged in a disorganized ...
11
Original Article Panax notoginseng saponins attenuates hypertrophic scar formation by inhibiting collagen synthesisin a rabbit ear model
... der, hypertrophic scarring occurs after deep trauma, surgical incision, or ...with hypertrophic scar- ring often experience serious cosmetic and functional impairment caused by various com- ...
8
Study on the efficacy of Palandu Ghrita in the Management of Sutured Clean Lacerated Wound w.s.r. To Hypertrophic scar
... Hypertrophic scar (4) is a type of scar characterized by hypertrophy or proliferation of mature fibroblast or fibrous tissue without proliferation of blood ...process. Hypertrophic scars are ...
5
MicroRNA-98 inhibits the cell proliferation of human hypertrophic scar fibroblasts via targeting Col1A1
... on hypertrophic scar tissues to verify the effect of ...human hypertrophic scars were ...trophic scar tissues and the matched normal skin tissues were prepared and the relative expression of ...
8
Experimental Study of 5 fluorouracil Encapsulated Ethosomes Combined with CO2 Fractional Laser to Treat Hypertrophic Scar
... tional laser treatment of hypertrophic scar. Moreover, microporous channel opening rates dropped to zero on 3 and 7 days, and the drug can no longer penetrate into the skin through these channels. These ...
12
EFFECT OF CRUDE EXTRACT AND PHYTOSTEROL FRACTION OF FUMARIA OFFICINALIS IN INDUCED HYPERTROPHIC SCAR OF RABBITS
... left for 48 h to acclimatize to the animal room conditions of controlled temperature (28–30°C), allowed free access to water ad libitum and food. Protocol of the current research was approved by the Institute Review ...
8
Investigating the potential of Shikonin as a novel hypertrophic scar treatment
... hs: hypertrophic scars; HSF: Hypertrophic scar-derived human skin fibroblasts; JNK1/2: c-Jun N-terminal kinase 1 and 2; Kc: Human skin keratinocytes; MAPK: Mitogen-activated protein kinases; p38 α / ...
13
iTRAQ-based proteomic profiling reveals different protein expression between normal skin and hypertrophic scar tissue
... the hypertrophic scar and normal skin tissue on a large scale from the same ...of hypertrophic scar formation which might guide us to propose new strategies against the hyper- trophic ...
8
Comparative effect and safety of verapamil in keloid and hypertrophic scar treatment: a meta-analysis
... In this meta-analysis, we did not find statistically significant difference between the therapeutic effects in the treatment of keloids and hypertrophic scars in the verapamil group and the nonverapamil group ...
7
Bone marrow concentrate-induced mesenchymal stem cell conditioned medium facilitates wound healing and prevents hypertrophic scar formation in a rabbit ear model
... Background: Hypertrophic scars (HSs) are formed via an aberrant response to the wound healing process. HSs can be cosmetic or can result in functional problems. Prolonged proliferation and remodeling phases ...
13
Comparative proteomic analysis of extracellular matrix proteins secreted by hypertrophic scar with normal skin fibroblasts
... of hypertrophic scars (HSs) is a fibroproliferative disorder of abnormal wound ...in scar formation, we comparatively analyzed matrix proteins secreted by normal skin fibroblasts (NSFs) and HS fibroblasts ...
8
Original Article Strongly induced hypertrophic scar in a rat model of tracheal stenosis
... Abstract: Objective: Previous rat models of tracheal stenosis have demonstrated a high mortality rate with little scar formation as well as interference by chemical factors. This study aimed to develop an improved ...
7
Adipose tissue-derived stem cells suppress hypertrophic scar fibrosis via the p38/MAPK signaling pathway
... Hypertrophic scars (HS) caused by extensive trauma, deep burns, and sometimes even standard surgery are usually characterized by abnormal extracellular matrix deposition and remodeling [1]. HS can be red, firm, ...
16
Original Article Gallic acid inhibits LPS induced hypertrophic scar inflammation via toll-like receptor 4/nuclear factor-κB/peroxisome proliferator-activated receptor γ signaling
... Abstract: Prolonged and enhanced inflammation is a common pathogenic feature of hypertrophic scars (HTS). Gallic acid (GA) is a naturally occurring plant phenol with lots of pharmacological activities, including ...
9
miR-145 Contributes to Hypertrophic Scarring of the Skin by Inducing Myofibroblast Activity
... This in vitro model was then used to an- alyze the differential expression of miR- NAs between nonstimulated skin fibro- blasts and differentiated myofibroblasts. miRNA-specific real-time PCR showed that miR-29b is ...
9
Effect of Carbon Dioxide Laser in Benign Skin Conditions
... Mode: SP of lesions lesions Spot size: Mild 0.2mm hypopigmentation Sittings: Two HYPERTROPHIC SCAR Age / S ite Sex 26Yrs Forehead Settings 1st Week 45th Day 2nd Month Power:1 Erythema No[r] ...
83
A comparitive study between placental extract versus silver sulfadiazine in 20-40 % fresh flame burns and scalds
... of hypertrophic scar in both the ...of hypertrophic scar and contracture may depend upon other factors like physiotherapy received and patients genetic ...
114
Original Article LPS induces activation of the TLR4 pathway in fibroblasts and promotes skin scar formation through collagen I and TGF-β in skin lesions
... In the animal model used in this study, we used the inhibitor of TLR4, TAK242, to treat the mice. The western blot results show that TAK242 could significantly down-regulate the expres- sion of TLR4 and its downstream ...
9
Original Article Role of thrombospondin-4 in fibroblasts from normal skin and hypertrophic scars
... and hypertrophic scars. Methods: Human normal skin-derived and hypertrophic scar-derived fibroblasts were cultured, and TSP4 gene expression was upregulated and downregulated in fibroblasts through ...
8