Hypertrophic scars
Keloids and Hypertrophic Scars: A Review of Risk Factors, Pathophysiology, Prevention, Management, and Treatments in Dermatology and Surgical Practice
... with hypertrophic scars remaining within the borders of the original wound and keloids extending beyond the original wound ...while hypertrophic scars push out the margins of the scar to ...
6
Study of the Effect of the Calcium Channel Blocker Verapamil on the Healing of Hypertrophic Scars and Keloids
... and hypertrophic scars differ from normal skin and normal scars by their rich vasculature, high mesenchymal cell density, and thickened epidermal cell ...between hypertrophic scars and ...
92
Original Article Role of thrombospondin-4 in fibroblasts from normal skin and hypertrophic scars
... Hypertrophic scars are a common pathologic wound healing state after repair, which usually manifests as dark red or raised tough tissue blocks near ...Superficial hypertrophic scars on the ...
8
Original Article HOXA9 regulates angiogenesis in human hypertrophic scars: induction of VEGF secretion by epidermal stem cells
... In the skin and in scar tissue, VEGF is mainly secreted by macrophages, endothelial cells, keratinocytes, and fibroblasts [33]. The expres- sion of VEGF is closely and positively related with vascular density and ...
10
Hypertrophic scars and keloids: Assessment of the effectiveness and outcome of different treatment modalities
... Different studies suggest that hypertrophic scarring and keloid formation are result of excess collagen accumulation in a healing wound. In keloids, type I procollagen levels are increased (compared to normal ...
7
Intralesional injection treatment of hypertrophic scars and keloids: a systematic review regarding outcomes
... The systematic review reported here combined data across studies in order to estimate the effects of intrale- sional treatments of hypertrophic scars and keloids with more precision than is possible in a ...
10
Original Article Emodin inhibits formation of hypertrophic scars through regulating the p38/MAPK signaling pathway
... Hypertrophic scars (HS) are features of a seri- ous fibrotic skin disorder following burns, trau- ma wounds, and surgical procedures ...for hypertrophic scars, including surgery, ...
8
Intralesional Cryotherapy Versus Intralesional Corticosteroid and 5-Fluorouracil in the Treatment of Hypertrophic Scars and Keloids: A Clinical Trial
... for hypertrophic scars and keloids include pressure therapies, silicone gel dressing, intralesional injection (corticosteroid, 5-FU, methotrexate, bleomycin), radiotherapy, cryotherapy and laser ...treat ...
7
Botulinum toxin type A (BTX-A) to improve the treatment of keloid and hypertrophic scars: A double-blinded randomized clinical trial
... and hypertrophic scars are the results of abnormal skin cells proliferation that usually cause major physical, psychological and cosmetic ...and hypertrophic scars treatment or ...
5
Management of keloids and hypertrophic scars: current and emerging options
... easy-to-use post-surgical procedure. Also, pressure garments may represent a promising alternative to intralesional TAC or cryotherapy for the treatment of hypertrophic scars and keloids in younger ...
12
Mechanical micronization of lipoaspirates for the treatment of hypertrophic scars
... Background: Hypertrophic scars cause cosmetic and functional problems for patients, and their treatment remains ...on hypertrophic scars. Methods: A model of hypertrophic scars ...
10
Diagnosis and Treatment of Keloids and Hypertrophic Scars—Japan Scar Workshop Consensus Document 2018
... In terms of the postoperative radiotherapy after partial excision, it has been suggested that the radiation dose should be equivalent that used in radiation monotherapy because its target is not only the excision wound ...
40
<p>Topical 5 fluorouracil cream versus combined 5 flurorouracil and fractional erbium YAG laser for treatment of severe hypertrophic scars</p>
... Background: Topical 5 fluorouracil (5-FU) has been reported as one of the standard treatments for hypertrophic scars (HTS). Ablative fractional laser was found to have promising results in the delivery of ...
8
Study of Intralesional Triamcinolone Alone and in Combination with Pressure Garments for the Treatment of Hypertrophic Scars and Correlation of Outcome with Expression of Transforming Growth Factor Beta
... TGF β -1, 2 and 3 mRNA expression was investigated in hypertrophic scars and controls by real-time PCR (Fig. 1). The study observed that the mRNA expression of TGF β-1 and TGF β-2 was increased up to 2.6 ...
6
Paclitaxel reduces formation of hypertrophic scars in the rabbit ear model
... of hypertrophic scars on rabbit ...of hypertrophic scars were established to observe the therapeutic effects of paclitaxel at different concentrations (12 mg/L, 24 mg/L, 48 mg/L, 96 mg/L, 18 ...
7
Original Article The role of miR-203a in hypertrophic scars and its mechanism
... Excessive scars, which may be caused by burns, lacerations, surgery, and vaccinations, physically and psychologically affect a patient’s quality of life, by causing pain, pruritus and con- ...tractures. ...
7
FACTORS INFLUENCING THE OCCURRENCE OF HYPERTROPHIC SCARS AMONG POSTOPERATIVE PATIENTS IN GARUT, INDONESIA
... There were significant relationships between infection of surgical wound, genetic history, the type of suture, and the occurrence of hypertrophic scars. The most dominant factor that influenced the ...
9
The molecular basis of hypertrophic scars
... HTS are characterized by abundant alpha-smooth muscle actin (α-SMA) producing myofibroblasts to- gether with more type III collagen than type I collagen. On the contrary, there is no α-SMA producing myofi- broblasts and ...
12
Biocompatible 5 Aminolevulinic Acid/Au Nanoparticle Loaded Ethosomal Vesicles for In Vitro Transdermal Synergistic Photodynamic/Photothermal Therapy of Hypertrophic Scars
... of hypertrophic scar ...human hypertrophic scar fibroblasts (HSF) as therapeutic targets, synergistic PDT/PTT of HS indicates that A/A-ES could enhance quantum yields of ROS by photothermal effect and ...
11
Autologous chyle fat grafting for the treatment of hypertrophic scars and scar-related conditions
... Samples were obtained from the scars before each treatment for histologic analysis. They were bisected and immediately fixed in 10% formalin. Subsequently, the scars were embedded in paraffin and cut into ...
8