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Hypobaric Hypoxia

Association of EGLN1 genetic polymorphisms with SpO2 responses to acute hypobaric hypoxia in a Japanese cohort

Association of EGLN1 genetic polymorphisms with SpO2 responses to acute hypobaric hypoxia in a Japanese cohort

... A signal of recent positive selection in Andean and Ti- betan populations has been commonly detected in a chromosomal region containing EGLN1 that encodes the PHD2 protein [10]. This suggests that EGLN1 may be a key ...

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Exposure to Hypobaric Hypoxia and Reoxygenation  Induces Transient Anxiety Like Behavior in Rat

Exposure to Hypobaric Hypoxia and Reoxygenation Induces Transient Anxiety Like Behavior in Rat

... A significant portion of the world population resides at high altitude regions. Apart from natives, natural beauty of the snow-clad peaks attracts a huge population of tourists every year to explore the high altitude. ...

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Cerium oxide nanoparticles protect rodent lungs from hypobaric hypoxia-induced oxidative stress and inflammation

Cerium oxide nanoparticles protect rodent lungs from hypobaric hypoxia-induced oxidative stress and inflammation

... Methods: A total of 48 animals were randomly divided into four equal groups (control [C], nanoceria treated [T], hypoxia [H], and nanoceria treated plus hypoxia [T+H]). Animals were injected ...

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Metabolism of asymmetric dimethylarginines is regulated in the lung developmentally and with pulmonary hypertension induced by hypobaric hypoxia

Metabolism of asymmetric dimethylarginines is regulated in the lung developmentally and with pulmonary hypertension induced by hypobaric hypoxia

... activity in the whole lung 24 hours after birth, and this would be expected to reduce tissue concentrations of NOS inhibitors and thereby increase NO generation. In animals exposed to hypobaric hypoxia to ...

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The objective assessment of the effects on cognition functioning among military personnel exposed to hypobaric hypoxia: A pilot fMRI study

The objective assessment of the effects on cognition functioning among military personnel exposed to hypobaric hypoxia: A pilot fMRI study

... The impact of long term or chronic exposure to high altitude on a healthy population has been studied exponentially. There is strong evidence to suggest that it leads to the development of cognitive impairment ...

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Markers of physiological stress during exercise under conditions of normoxia, normobaric hypoxia, hypobaric hypoxia and genuine high altitude

Markers of physiological stress during exercise under conditions of normoxia, normobaric hypoxia, hypobaric hypoxia and genuine high altitude

... Purpose To investigate whether there is a differential response at rest and following exercise to conditions of genuine high altitude (GHA), normobaric hypoxia (NH), hypobaric hypoxia (HH), and ...

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Original Article The hypobaric hypoxia environment impairs bone strength and quality in rats

Original Article The hypobaric hypoxia environment impairs bone strength and quality in rats

... by hypobaric hypoxia environment; however, it also has some limita- ...baric hypoxia is just one, although the most important, characteristic at high ...by hypobaric hypoxia, which play ...

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The protective effects of chronic intermittent hypobaric hypoxia pretreatment against collagen-induced arthritis in rats

The protective effects of chronic intermittent hypobaric hypoxia pretreatment against collagen-induced arthritis in rats

... Accumulating evidence showed that chronic intermit- tent hypobaric hypoxia (CIHH) has beneficial effects on the body. For example, CIHH protects heart, central nervous system, and liver against ...

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Original Article A rat model of sustained hypobaric hypoxia-induced pulmonary hypertension

Original Article A rat model of sustained hypobaric hypoxia-induced pulmonary hypertension

... to hypobaric hypoxia environment at the simulate-altitude of 5,000 meter for 4 weeks caused the pathological remodeling of pulmonary vascular walls men- tioned above, including the increased thick- ness of ...

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Myocardial Interstitial Matrix as Novel Target for Succinic Acid Treatment Strategies during Experimental Hypobaric Hypoxia

Myocardial Interstitial Matrix as Novel Target for Succinic Acid Treatment Strategies during Experimental Hypobaric Hypoxia

... of hypoxia and peroxidation in the genesis of many cardiovascular diseases has stimulated the development of strategies that can enhance the energy-producing functions of ...of hypoxia-related ...to ...

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Acute Mountain Sickness Symptoms Depend on Normobaric versus Hypobaric Hypoxia

Acute Mountain Sickness Symptoms Depend on Normobaric versus Hypobaric Hypoxia

... Acute mountain sickness (AMS), characterized by headache, nausea, fatigue, and dizziness when unacclimatized individuals rapidly ascend to high altitude, is exacerbated by exercise and can be disabling. Although AMS is ...

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Neuroprotective effects of sea buckthorn leaf extract against hypobaric hypoxia and post-hypoxic reoxygenation induced hippocampal damage in rats.

Neuroprotective effects of sea buckthorn leaf extract against hypobaric hypoxia and post-hypoxic reoxygenation induced hippocampal damage in rats.

... to hypobaric hypoxia and reoxygenation has been a major concern in high altitude ...research. Hypobaric hypoxic damage is a reversible phenomenon which tends to normalise gradually after the stress ...

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Rhodiola crenulata extract counteracts the effect of hypobaric hypoxia in rat heart via redirection of the nitric oxide and arginase 1 pathway

Rhodiola crenulata extract counteracts the effect of hypobaric hypoxia in rat heart via redirection of the nitric oxide and arginase 1 pathway

... to hypoxia due to its property of high oxygen uptake ...to hypobaric hypoxia can consequently result in exaggerated arterial hypoxemia and lead to cardiac dysfunction including SCD [2, ...abolished ...

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Effects of prolonged exposure to hypobaric hypoxia on oxidative stress, inflammation and gluco insular regulation : the not so sweet price for good regulation

Effects of prolonged exposure to hypobaric hypoxia on oxidative stress, inflammation and gluco insular regulation : the not so sweet price for good regulation

... sustained hypobaric hypoxia at high-altitude appear to become insulin-resistant while they are in negative energy ...of hypoxia-induced insulin resistance have identified two core causal mechanisms: ...

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Protective effects of polyunsatutared fatty acids supplementation against testicular damage induced by intermittent hypobaric hypoxia in rats

Protective effects of polyunsatutared fatty acids supplementation against testicular damage induced by intermittent hypobaric hypoxia in rats

... angiogenesis, metabolic and hypoxic adaptation and re- sistance to oxidative stress and increase invasive proper- ties [38]. In ischemia induced by hypobaric hypoxia, HIF-1α transcriptionally activates ...

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Combined intermittent hypobaric hypoxia and muscle electro stimulation: a method to increase circulating progenitor cell concentration?

Combined intermittent hypobaric hypoxia and muscle electro stimulation: a method to increase circulating progenitor cell concentration?

... The small samples used in these different studies make it difficult to draw any firm conclusions, since there are many factors that might influence the results. It is worth noting, however, that whereas many types of ...

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Relationship between mitochondrial haplogroup and physiological responses to hypobaric hypoxia

Relationship between mitochondrial haplogroup and physiological responses to hypobaric hypoxia

... Although the relationship between mtDNA poly- morphism and high-altitude adaptation has been re- ported [6, 17], there have been no studies on the relationship between mtDNA polymorphism and the physiological state at ...

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Original Article Acute exposure to hypobaric hypoxia upregulates the expression of hypoxia-inducible factor-1α and vascular endothelial growth factor

Original Article Acute exposure to hypobaric hypoxia upregulates the expression of hypoxia-inducible factor-1α and vascular endothelial growth factor

... Abstract: Hypoxia is a stress factor frequently encountered during flight and a common cause of tissue and cell injury experienced by in-flight ...of hypoxia on the body can vary depending on the duration ...

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Effect of Hypobaric Hypoxia on Cognitive Functions and Potential Therapeutic Agents

Effect of Hypobaric Hypoxia on Cognitive Functions and Potential Therapeutic Agents

... Hypobaric hypoxia (HBH) at HA is known to disrupt cognitive functions in humans ...moderate hypoxia for 1 h at 4 400 m, and these effects were exacerbated at increasing altitudes ...HA hypoxia ...

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Effects of high-intensity interval training while using a breathing-restrictive mask compared to intermittent hypobaric hypoxia

Effects of high-intensity interval training while using a breathing-restrictive mask compared to intermittent hypobaric hypoxia

... for economic changes. Another limitation of the present study is the assumption that the ETM adds 914 m of elevation to the current elevation. The estimated change in elevation for each flux valve claimed by the mask ...

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