Hypothalamic Pituitary Adrenal Axis
Reduced hypothalamic pituitary adrenal axis activity in chronic multi site musculoskeletal pain: partly masked by depressive and anxiety disorders
... This study found hypoactive HPA-axis function in chronic multi-site musculoskeletal pain (Table 2), while depressive and some types of anxiety disorders have pre- viously been associated with hypercortisolemia ...
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Prenatal dexamethasone exposure induces changes in nonhuman primate offspring cardiometabolic and hypothalamic pituitary adrenal axis function
... the third trimester (29). Clinical trials involving antenatal gluco- corticoid therapy have also been scrutinized retrospectively and indicate that exposure to prenatal glucocorticoids increases blood pressure in ...
11
Cortisol reactivity and suicidal behavior: investigating the role of hypothalamic pituitary adrenal axis responses to stress in suicide attempters and ideators
... Dysregulated hypothalamic-pituitary-adrenal (HPA) axis activity, as measured by cortisol levels, is one potential risk ...HPA axis activity is associated with some forms of suicidal ...
29
The vasopressin V1b receptor critically regulates hypothalamic pituitary adrenal axis activity under both stress and resting conditions
... the hypothalamic paraventricular nuclei and in the supraoptic nuclei that project to the poste- rior ...stimulate pituitary ACTH release both in vitro and in vivo ...
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Suppression of hypothalamic pituitary adrenal axis responsiveness to stress in a rat model of acute cholestasis
... the hypothalamic-pituitary-adrenal axis, we evaluated rats with acute cholestasis caused by bile duct resection (BDR) and sham-operated and unoperated ...
7
Individual Differences in Stress Responsiveness of the Hypothalamic Pituitary Adrenal Axis and Its Vasopressinergic Regulation in Old Monkeys
... anterior pituitary in response to acute stress in animals with DAB may be due to increased vasopressin-producing activity of the parvicellular neurons of the PVN, ...the pituitary portal vascular system ...
15
Excess corticotropin releasing hormone binding protein in the hypothalamic pituitary adrenal axis in transgenic mice
... the pituitary glycoprotein hormone a -subunit ( a -GSU) ...terior pituitary (7) rather than the gonadotropes and thyro- tropes, CRH-BP is thought to act as a secreted ...heterogeneous pituitary, ...
10
Effects of an exercise and hypocaloric healthy eating intervention on indices of psychological health status, hypothalamic pituitary adrenal axis regulation and immune function after early stage breast cancer: a randomised controlled trial
... HPA axis regulation in the intervention group but further re- search is needed to confirm this and delineate the precise determinants of HPA axis ...
11
Evidence against hypothalamic pituitary adrenal axis suppression in the antidiabetic action of leptin
... [HPT] axis, and activation of the hypotha- lamic-pituitary-adrenal [HPA] axis), the degree of hyperglycemia was not significantly affected ...HPA axis seems unlikely to fully explain ...
6
Effects of an exercise and hypocaloric healthy eating intervention on indices of psychological health status, hypothalamic pituitary adrenal axis regulation and immune function after early stage breast cancer : a randomised controlled trial
... The importance of healthy lifestyle behaviours to prevent the adverse effects of weight gain after a breast cancer diagnosis is widely acknowledged and sustainable lifestyle change was recently identified as one of the ...
20
Effects of an exercise and hypocaloric healthy eating intervention on indices of psychological health status, hypothalamic pituitary adrenal axis regulation and immune function after early stage breast cancer : a randomised controlled trial
... HPA axis regulation in breast cancer patients and other populations ...HPA axis dysregulation in previous studies ...HPA axis regulation, which probably explains why the intervention had no effect on ...
20
The hypothalamic pituitary gonadal axis in mood disorders
... evaluate pituitary and adre- nal ...HPA axis activation, disrupted HPG functioning, and ...HPA axis overactivity are frequent findings in major depression, and increased cerebrospinal fluid levels of ...
16
Adrenal hypoplasia congenita with hypogonadotropic hypogonadism: evidence that DAX 1 mutations lead to combined hypothalmic and pituitary defects in gonadotropin production
... elevated adrenal steroid ...large adrenal vacuoles. The description of his adrenal glands was consistent with adrenal hypoplasia congenita, although the diagnosis was not made at the ...of ...
9
SOX2 regulates the hypothalamic pituitary axis at multiple levels
... the pituitary-specific transcription factor POU class 1 homeobox 1 (POU1F1) as well as severe disruption of somatotroph and thyrotroph ...cient hypothalamic stimulation of gonadotrophs, that underlies ...
13
Th e eff ect of orally administered Budesonide on the hypothalamic-pituitary-adrenal axis in dogs with infl ammatory bowel disease
... the hypothalamic-pituitary-adrenal (HPA) axis in dogs with inflammatory bowel ...HPA axis was analysed in 21 dogs with inflammatory bowel ...HPA axis activity was correlated with ...
8
An investigation of kynurenine pathway metabolism, the hypothalamic pituitary adrenal axis, and inflammatory markers in Major Depressive Disorder
... the hypothalamic-pituitary adrenal (HPA) axis and activation of the inflammatory response system are known to play a role in depression ...
329
Recent advances in understanding Cushing disease: resistance to glucocorticoid negative feedback and somatic USP8 mutations
... the pituitary. However, it is pos- sible that other hypothalamic factors allow or facilitate this ...of hypothalamic-pituitary-adrenal (HPA) axis regulation with an emphasis on ...
8
A low cortisol response to stress is associated with musculoskeletal pain combined with increased pain sensitivity in young adults: a longitudinal cohort study
... OC use, smoking, body mass index (BMI), physical ac- tivity level and depressive symptoms were measured at 17 or 18 years of age and selected as covariates, as each of them has been related to HPA axis function ...
11
Biomarkers of hypothalamic-pituitary-adrenal axis activity in mice lacking 11β-HSD1 and H6PDH
... HPA axis control and enhanced circadian HPA drive (Harris et ...increased hypothalamic GC receptor expres- sion, increasing feedback sensitivity (Carter et ...HPA axis activation, with grossly ...
7
The determinants of susceptibility/resistance to adjuvant arthritis in rats
... HPA axis response at the onset of arthritis (with germ-free F344 rats but not conventional F344 rats showing an increase in plasma corticosterone) [56], and an alteration of the T-cell effector/T-cell regulatory ...
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