i collagen
Diminished type I collagen synthesis and reduced alpha 1(I) collagen messenger RNA in cultured fibroblasts from patients with dominantly inherited (type I) osteogenesis imperfecta
... Type I osteogenesis imperfecta (OI) is characterized clinically by a moderate fracture frequency with minimal bone deformity and dominant ...1(I) collagen type ratio and an elevated alpha 1(I) ...
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Characterization of the Interaction Between Bone Sialoprotein and Type I Collagen
... type I collagen (14, ...the collagen molecule at a site with a surface chemistry that is, at least in part, ...Type I collagen has an isoelectric point of ...the collagen ...
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Influence of telopeptides on the structural and physical properties of polymeric and monomeric acid-soluble type I collagen
... monomeric collagen which is extractable in weak acidic ...the collagen consists of insoluble, highly cross- linked polymerized fibers of type I collagen (polymeric collagen) with a ...
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Relative orientation of collagen molecules within a fibril: a homology model for homo sapiens type I collagen
... the collagen molecules aggregate as a result of the intermolecular forces, before later forming the covalent interactions via the mature enzymatic ...the collagen mole- cules will be to maximise the number ...
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Type I collagen gene suppresses tumor growth and invasion of malignant human glioma cells
... type I collagen molecules are distributed as heter- otrimers [α1(I)] 2 α2(I), and a small number of molecules exist as homotrimers [α1(I)] 3 ...type I collagen is the most ...
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Characterisation of the immune response to type I collagen in scleroderma
... This study was conducted to examine the frequency, phenotype, and functional profile of T lymphocytes that proliferate in response to type I collagen (CI) in patients with scleroderma (SSc). Peripheral ...
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Rescue of type I collagen-deficient phenotype by retroviral-vector-mediated transfer of human pro alpha 1(I) collagen gene into Mov-13 cells.
... The proalI collagen cDNA is functional because infection of Mov-13 cells with the vector rescued the mouse proa2I chain and restored type I collagen expression.. Our experiments demonstr[r] ...
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A synthetic peptide derived from the sequence of a type I collagen receptor inhibits type I collagen mediated platelet aggregation
... type I col- lagen–induced platelet aggregation and the release of ATP in a dose-dependent ...III collagen receptor ...types I and III collagen– induced platelet aggregation and the release of ...
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<p>Effect of Intracorporeal Human Adipose–Derived Stem Cells (hADSCs) on Corpora Cavernosa Transforming Growth Factor β1 (TGFβ1) and Collagen Type I Concentration in Wistar Rat Priapism Model</p>
... type I collagen con- centration over time in the priapism control ...type I collagen also tended to increase at the second and fourth weeks of therapy, but when compared with the control ...
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Diagnostic significance of biochemical indicators of liver fibrogenesis in adolescents with obesity
... of collagen of ...is collagen type IV, which is the main structural element of cellular basement ...of collagen, in particular type I, leadstotheformationofbridge-likefibrosisandul- ...
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Non-invasive biomarkers derived from the extracellular matrix associate with response to immune checkpoint blockade (anti-CTLA-4) in metastatic melanoma patients
... III collagen [17], C1M is from MMP-degraded type I collagen [25], C3M is from MMP-degraded type III collagen [26], C4M is from MMP-degraded type IV collagen [27] and VICM is from ...
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Tumour cells down-regulate CCN2 gene expression in co-cultured fibroblasts in a Smad7- and ERK-dependent manner
... type I collagen gene expression in neighbouring fibroblasts via such secreted ...type I collagen expression in fibro- blasts was dependent on the contacts with or close prox- imity of the ...
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The healing effect of the collagen-glycosaminoglycan copolymer on corneal thinning
... Type I collagen accounts for about 85% of the fibrillar collagen in human corneal ...V collagen, type I collagen are crucial for corneal transparency ...porous ...
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Lung collagen heterogeneity Synthesis of type I and type III collagen by rabbit and human lung cells in culture
... of collagen synthesis that represents 4-5% of the total amino acids incorporated into lung ...this collagen is not homogeneous but rather is composed of at least two collagen types, I and II, ...
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Overexpression of Interleukin-18 Aggravates Cardiac Fibrosis and Diastolic Dysfunction in Fructose-Fed Rats
... type I collagen (forward 5′-GGA GAG TAC TGG ATC GAC CCT AAC-3′; reverse 5′-CTG ACC TGT CTC CAT GTT GCA-3′), type III collagen (forward 5′-GAA AAA ACC CTG CTC GGA ATT-3′; reverse 5′- GGA TCA ACC CAG ...
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Safety, tolerability and efficacy of intra articular Progenza in knee osteoarthritis: a randomized double blind placebo controlled single ascending dose study
... II collagen C2C pep- tide (C2C) and C-terminal telopeptide of type II collagen (CTX-II); serum: macrophage migration inhibitory factor (MIF), HA and C-terminal telopeptide of type I collagen ...
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<p>Multi-Layered Polyamide/Collagen Scaffolds with Topical Sustained Release of N-Acetylcysteine for Promoting Wound Healing</p>
... study, collagen was chosen due to the following: i) collagen can achieve sustained drug release via a simple chemical crosslinking method (using the NHS-EDC mixture); ii) given that PA is highly ...
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Clonorchis sinensis lysophospholipase A upregulates IL 25 expression in macrophages as a potential pathway to liver fibrosis
... or collagen type I (Collagen-I) (Abcam, London, UK) overnight at 4 ...and collagen type I staining was analyzed with Image-Pro Plus ...
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Identification of type IV collagen exposure as a molecular imaging target for early detection of thoracic aortic dissection
... IV collagen; Col-I: type I collagen; Col-III: type III collagen; CDR: Col-IV-DOTA-Gd-rhodamine B; MRI: magnetic resonance imaging; NSE: normalized signal enhancement; TAD: thoracic ...
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Collagen types I and II distribution: a relevant indicator for the functional properties of articular cartilage in immobilised and remobilised rabbit knee joints
... females collagen type II is possibly influenced by oestrogen level, where oestrogen counters the acceleration of type II collagen degradation ...type I collagen could be detected ...of ...
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