IFN-γ production
IFNG +874T/A polymorphism is not associated with American tegumentary leishmaniasis susceptibility but can influence Leishmaniainduced IFN γ production
... the IFN-γ genotypic analysis in ...in IFN-γ genes may influence the levels of released protein [11] which in turn could increase the sus- ceptibility to leishmaniasis or predispose for ...
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Immunization of mice with soluble lysate of interferon gamma expressing Plasmodium berghei ANKA induces high IFN-γ production
... that, IFN-γ production plays a critical role in mediating protective immunity against both the pre-erythrocytic and blood-stage parasites ...producing IFN-γ responses would be highly ...
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Decreased ex vivo production of interferon gamma is associated with severity and poor prognosis in patients with lupus
... vivo IFN-γ production after stimulation with PHA decreased in patients with active ...that IFN-γ-producing T cells were de- creased in patients with active lupus [21], which is simi- ...
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Differential expression of three T lymphocyte activating CXC chemokines by human atheroma associated cells
... augments IFN-γ production from Th1 cells (57) and thus may help establish an autocrine loop that serves to drive the inflammatory response within the diseased ...these IFN-γ–inducible ...
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Individual T helper cells have a quantitative cytokine memory
... of IFN-γ production was a stable feature of individual Th1 cells that was memorized for at least one month in vivo, even upon immunological ...produced IFN- amount defined a cell’s capacity ...
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T cell–dependent production of IFN γ by NK cells in response to influenza A virus
... induces production of innate cytokines, including various IFNs and interleukins ...I IFN and IL-12, which have profound effects on other immune cell sub- sets ...induce production of ...
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Dysregulated Sonic hedgehog signaling and medulloblastoma consequent to IFN α–stimulated STAT2 independent production of IFN γ in the brain
... factor, IFN-γ, as the most likely candidate, since this cytokine was capable of inducing Shh gene expression by cultured cerebellar granule ...like IFN-γ, IFN-α upregulated STAT1 gene ...
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STIM1 controls T cell–mediated immune regulation and inflammation in chronic infection
... enhance IFN-γ expression ...impaired IFN-γ production (41, 43, 63), suggesting that NFAT1 and NFAT4 promote Th1 cell ...impaired IFN-γ expression in STIM1-deficient mice ...
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The in vitro and ex vivo effect of Auranta 3001 in preventing Cryptosporidium hominis and Cryptosporidium parvum infection
... Also, IFN-γ results showed that Auranta 3001 did not have any effect on IFN-γ production in HCT-8 cells, keeping concentrations at similar levels with the controls, whereas in bovine ...
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The clinical implication and molecular mechanism of preferential IL 4 production by modified glycolipid stimulated NKT cells
... cell production of IFN-γ is more susceptible to the sphingosine length of glycolipid ligand than that of IL-4 and that the length of the sphingosine chain deter- mines the duration of NKT cell ...
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... and IFN-γ being signature cytokines of T helper Th1/Th17 cells, most of the studies have proven their role in psoriasis on the basis of expression level changes in mRNA ...high production of Th1 and ...
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T cell–mediated vascular dysfunction of human allografts results from IFN γ dysregulation of NO synthase
... Neutralizing IFN-γ completely prevented both vascular dysfunction and changes in NOS expression; neutralizing TNF reduced IFN-γ production and partially prevented ...
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Immune Responses of CD4 + T-Cells of MDR-TB Patients to M.Tuberculosis Total Lipid Antigens
... of IFN- γ production in MDR-TB and TB patients is not due to the increase of IL-10 ...of IFN-γ down regulation in CD4 + T cells of TB and MDR-TB ...
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Cerebral vessel laminins and IFN γ define Trypanosoma brucei brucei penetration of the blood brain barrier
... phocytes accumulate between the two distinct basement mem- branes surrounding cerebral vessels — the endothelial and paren- chymal basement membranes — which contain different laminin isoforms defined by specific laminin ...
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Analysis of the effect of the active compound of green tea (EGCG) on the proliferation of peripheral blood mononuclear cells
... [36]. Hu and colleagues demonstrated that EGCG signifi- cantly inhibited the proliferation of B and T cells in cul- ture [37]. Similarly, Wilasrusmee and co-workers and Zvetkova and colleagues reported that green tea ...
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Interferon-γ acts as a regulator in the trade-off between phagocytosis and production performance in dwarf chickens
... in production traits are always more profitable, but they also put the birds at in- creased risk of stress and disease because of unbal- anced resource allocation ...high production efficiency in broilers ...
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Polymorphisms in Chlamydia trachomatis tryptophan synthase genes differentiate between genital and ocular isolates
... avoid IFN- γ –mediated host defense mechanisms and establish persistent infection, partic- ularly in the female ...of IFN- γ ...of IFN-γ could result in the development of ...
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Lack of interferon-γ receptor results in a microenvironment favorable for intestinal tumorigenesis
... by IFN-γ during inflammation ...while IFN-γ signaling is essential for tumor immunity, excessive activation of IFN-γ signaling pathway may not necessarily lead to better outcomes ...
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Tumor suppressor TET2 promotes cancer immunity and immunotherapy efficacy
... by IFN-γ (47–50). To test whether TET2 mediates IFN-γ–stimulated expression of these 4 genes, we treated B16-OVA and MC38 as well as THP-1 human monocytic cells, commonly used to study the ...
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Local production of CCL3, CCL11, and IFN γ correlates with disease severity in murine parainfluenza virus infection
... interferon- γ , CXCL10 (IP-10), and CCL3 (MIP-1 α ) were significantly higher in lung tissue homogenates from mice inoculated with ...interferon- γ and CCL3 all correlated strongly with disease ...
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