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IGF—insulin-like growth factor

Targeting insulin-like growth factor axis in hepatocellular carcinoma

Targeting insulin-like growth factor axis in hepatocellular carcinoma

... of IGF- 1R monoclonal ...of growth hormone could also contribute to the disappointing activity of this class of ...both IGF-1 and IGF-2 to IGF-1R ...expressing IGF-1R ...to ...

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Insulin-Like Growth Factor Axis Expression in Dental Pulp Cells Derived From Carious Teeth

Insulin-Like Growth Factor Axis Expression in Dental Pulp Cells Derived From Carious Teeth

... main IGF species expressed in dental pulp (Reichenmiller et ...of IGF-2 gene expression in cDPCs observed in the current ...Interestingly, IGF-2 was highly expressed in DPCs isolated from deciduous ...

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Expression of the insulin-like growth factor (IGF) system and steroidogenic enzymes in canine testis tumors

Expression of the insulin-like growth factor (IGF) system and steroidogenic enzymes in canine testis tumors

... the IGF system among the different types of tumors is not very dramatic when compared to normal testis ...and growth. In order to deter- mine whether the IGF system is involved in the initiation of ...

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Growth factor expression in aorta of normotensive and hypertensive rats

Growth factor expression in aorta of normotensive and hypertensive rats

... platelet-derived growth factor (PDGF) B chain and PDGF A chain, insulin-like growth factor (IGF)-I and IGF-II, endothelial cell growth factor (ECGF), ...

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Short-Term Growth Hormone Treatment in Girls With Turner Syndrome Decreases Fat Mass and Insulin Sensitivity: A Randomized, Double-Blind, Placebo-Controlled, Crossover Study

Short-Term Growth Hormone Treatment in Girls With Turner Syndrome Decreases Fat Mass and Insulin Sensitivity: A Randomized, Double-Blind, Placebo-Controlled, Crossover Study

... GH, insulin-like growth factor I (IGF-I), IGF binding proteins (IGFBPs), insulin, glucose, and lipolytic and gluconeogenic precursors were assayed, followed by an oral ...

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Growth Hormone Increases Breast Milk Volumes in Mothers of Preterm Infants

Growth Hormone Increases Breast Milk Volumes in Mothers of Preterm Infants

... Maternal milk production and plasma concentrations of insulin-like growth factor-i (IGF-i), insulin-like growth factor binding protein-3 (IGFBP-3), and growth hormone (GH) were determine[r] ...

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Changes in pain and insulin like growth factor 1 in fibromyalgia during exercise: the involvement of cerebrospinal inflammatory factors and neuropeptides

Changes in pain and insulin like growth factor 1 in fibromyalgia during exercise: the involvement of cerebrospinal inflammatory factors and neuropeptides

... of IGF-1 combined with high chronic levels of CSF SP may lead to long-term adaptation to tol- erate physical ...Thus, IGF-1 may promote resilience to pain in the ...with IGF-1 reversed neuronal ...

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Thyroid stimulating hormone and insulin like growth factor 1 synergize to elevate 1,2 diacylglycerol in rat thyroid cells  Stimulation of DNA synthesis via interaction between lipid and adenylyl cyclase signal transduction systems

Thyroid stimulating hormone and insulin like growth factor 1 synergize to elevate 1,2 diacylglycerol in rat thyroid cells Stimulation of DNA synthesis via interaction between lipid and adenylyl cyclase signal transduction systems

... TSH, IGF-1 and insulin on FRTL- 5 cell content of 1,2-diacylglycerol (1,2-DG), the endogenous activator of protein kinase C, were ...TSH, IGF-1 and insulin caused increases in cellular 1,2-DG ...

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Insulin like growth factor signaling regulates developmental trajectory associated with diapause in embryos of the annual killifish Austrofundulus limnaeus

Insulin like growth factor signaling regulates developmental trajectory associated with diapause in embryos of the annual killifish Austrofundulus limnaeus

... of IGF-I and IGF-II abundance in the present study support a role for increased abundance of IGFs fueling this compensatory acceleration in the rate of ...both IGF-I and IGF-II increase ...

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Insulin like growth factor I stimulates lipid oxidation, reduces protein oxidation, and enhances insulin sensitivity in humans

Insulin like growth factor I stimulates lipid oxidation, reduces protein oxidation, and enhances insulin sensitivity in humans

... of insulin-like growth factor I (IGF-I) on fuel oxidation and insulin sensitivity, eight healthy subjects were treated with saline and recombinant human (IGF-I (10 ...day. ...

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The Insulin-like Growth Factor Binding Protein Superfamily: New Perspectives

The Insulin-like Growth Factor Binding Protein Superfamily: New Perspectives

... of IGF peptides, typically from minutes to hours; and 3) modulate the access of IGF ligands to their receptors, thereby regulating IGF ...latter, IGF-independent activities, refers to the ...

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Acute effects of physical exercise on the serum insulin like growth factor system in women with fibromyalgia

Acute effects of physical exercise on the serum insulin like growth factor system in women with fibromyalgia

... free IGF-1 may be due to activity induced uptake of IGF-1 from the ...blood. IGF-1 is ac- tively taken up from blood into the central nervous sys- tem via the blood brain barrier and via the choroid ...

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Evaluation of effectiveness of concentrated growth factor on osseointegration

Evaluation of effectiveness of concentrated growth factor on osseointegration

... many growth factors such as bone morphogenetic protein (BMP), platelet-derived growth factor (PDGF), insulin-like growth factor (IGF), vascular endothelial ...

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Original Article IGF-1 and IGFBP-3 polymorphisms predict risk for non-traumatic osteonecrosis of the femoral head

Original Article IGF-1 and IGFBP-3 polymorphisms predict risk for non-traumatic osteonecrosis of the femoral head

... of Insulin-Like growth factor-I (IGF-1) and Insulin-like growth factor- binding protein-3 (IGFBP-3) polymorphisms in non-traumatic osteonecrosis of the ...

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Association of Insulin-like Growth Factor I and Insulin-like Growth Factor–Binding Protein-3 With Intelligence Quotient Among 8- to 9-Year-Old Children in the Avon Longitudinal Study of Parents and Children

Association of Insulin-like Growth Factor I and Insulin-like Growth Factor–Binding Protein-3 With Intelligence Quotient Among 8- to 9-Year-Old Children in the Avon Longitudinal Study of Parents and Children

... The characteristics of the children included in this analysis are given in Table 1. Girls had higher levels of both IGF-I and IGFBP-3. Those with a missing IQ measure tended to have somewhat lower levels of ...

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Human conditions of insulin like growth factor I (IGF I) deficiency

Human conditions of insulin like growth factor I (IGF I) deficiency

... [314] insulin resistance [309,310,312], diabetes [315], obesity [309,311], elevated C-reactive protein [316], waist-to-hip ratio [309], reduced coronary flow reserve [279], smoking [317], sedentary life [318] and ...

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Expression and clinical significance of IGF-1, IGFBP-3, and IGFBP-7 in serum and lung cancer tissues from patients with non-small cell lung cancer

Expression and clinical significance of IGF-1, IGFBP-3, and IGFBP-7 in serum and lung cancer tissues from patients with non-small cell lung cancer

... of insulin-like growth factor 1 (IGF-1), insulin-like growth factor binding protein 3 (IGFBP-3), and insulin-like growth factor ...

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A characteristic signature of insulin-like growth factor (IGF) axis expression during osteogenic differentiation of human dental pulp cells (hDPCs): Potential co-ordinated regulation of IGF action

A characteristic signature of insulin-like growth factor (IGF) axis expression during osteogenic differentiation of human dental pulp cells (hDPCs): Potential co-ordinated regulation of IGF action

... Although we show that IGFBP-4 concentrations are not altered following osteogenic di ff erentiation of hDPCs, it is well established that the activity of IGFBP-4 in fi broblast and osteoblast cultures can be modified by ...

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Combined sprint and resistance training abrogates age differences in somatotropic hormones

Combined sprint and resistance training abrogates age differences in somatotropic hormones

... serum growth hormone (GH), insulin-like growth factor-1 (IGF-1) and insulin-like growth factor-binding protein-3 (IGFBP-3) in re- sponse to a combined ...

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Characterization of Compensatory Growth in Hybrid Striped Bass (Morone chrysops X Morone saxatilis): Hormones and Mechanisms

Characterization of Compensatory Growth in Hybrid Striped Bass (Morone chrysops X Morone saxatilis): Hormones and Mechanisms

... Compensatory growth (CG) is a period of growth acceleration that exceeds normal rates after animals are alleviated of certain growth-stunting ...a growth-stunting / catabolic condition that, ...

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