IGFBP-4
Prognostic value of the Stanniocalcin-2/PAPP-A/IGFBP-4 axis in ST-segment elevation myocardial infarction
... intact IGFBP-4 were from AnshLabs, Webster, TX, ...intact IGFBP-4 was measured with an enzyme linked immunosorbent assay (AL-124) with a limit of detection of ...
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IGFBP-4 and −5 are expressed in first-trimester villi and differentially regulate the migration of HTR-8/SVneo cells
... ition. IGFBP-4 was able to block the migration-stimulating effects of both IGF-I and IGF-II to control ...contrast, IGFBP-5 was able to inhibit the migration- stimulating effects of IGF-II to control ...
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IGFBP-4 tumor and serum levels are increased across all stages of epithelial ovarian cancer
... serial IGFBP-4 readings above threshold was higher in the AWD group compared to the NED group, again suggesting that high serum levels of IGFBP-4 may be indicative of disease ...EOC ...
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Evolution of ancient functions in the vertebrate insulin like growth factor system uncovered by study of duplicated salmonid fish genomes
... Unfortunately, IGFBP-6 models were necessarily excluded from further analysis owing to poor inferred local model qual- ity in the critical NBP thumb region (fully discussed in the Materials and ...key ...
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Altered protein expression in serum from endometrial hyperplasia and carcinoma patients
... glycoprotein; IGFBP-4: insulin-like growth factor-binding protein 4; IHRP: inter-alpha-trypsin inhibitor family heavy chain-related protein; IPI: international Protein Index; ITIH4: ...
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IGFBP-2 and -3 co-ordinately regulate IGF1 induced matrix mineralisation of differentiating human dental pulp cells
... was IGFBP-4 N IGFBP-5 N IGFBP-6 N IGFBP-2 N IGFBP-3 N IGFBP-1 – ...1). IGFBP-4, -5 and -6 expression did not alter during differentiation of ...that ...
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Original Article IGFBP-3 may trigger osteoarthritis by inducing apoptosis of chondrocytes through Nur77 translocation
... including IGFBP-2, IGFBP-3, IGFBP-4, especially the middle one elevated ...of IGFBP-3 were observed by Whellams in the OA synovial fluid [6] and he thought maybe there were a ...
12
Fisch, Thomas Martin (2005): Effects of insulin-like growth factor-binding protein-2 (IGFBP-2) overexpression on adrenal and renal growth processes and functions: findings in transgenic mouse models. Dissertation, LMU München: Tierärztliche Fakultät
... overexpressing IGFBP-1 exhibit several organ-related alterations, with the brain and kidney being most affected (see under ...homeostasis. IGFBP-2 transgenic mice are presented in depth below. ...
172
Transcriptional regulation of the IGF signaling pathway by amino acids and insulin like growth factors during myogenesis in Atlantic salmon
... and IGFBP expression by amino acids and insulin-like growth factors was also ...5.2, IGFBP-6, IGFBP-rP1, ...(IGF-I, IGFBP-4, FGF2 and IGF-IRb) and terminal differentiation and myotube ...
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Zhou, Rui (2003): Functional analysis of insulin-like growth factor binding protein -4 and -6 in transgenic mice. Dissertation, LMU München: Tierärztliche Fakultät
... context IGFBP-4 is particularly interesting for several reasons: (i) IGFBP-4 is the second most abundant IGFBP in the placental bed (Han et ...increased IGFBP-4 ...
165
Journal of Applied Pharmaceutical Science
... one. IGFBP-4 is 237 amino acid polypeptide chain that contains N-linked gylcosylation site and commonly exists in biological fluids as a doublet 24 ...after IGFBP-3. Northern blot analysis has ...
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Protease resistant form of insulin like growth factor binding protein 5 is an inhibitor of insulin like growth factor I actions on porcine smooth muscle cells in culture
... to IGFBP-5 that is present in the interstitial fluid, IGFBP-5 that is sequestered in the extracellular matrix appears to be protected from ...with IGFBP-5 results in enhanced responsiveness to IGF-I ...
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The Histone H3K9 Demethylase Kdm3b Is Required for Somatic Growth and Female Reproductive Function
... that IGFBP-2 and IGFBP-4 levels were compa- rable, but the IGFBP-3 levels were much lower in Kdm3bKO mice versus WT mice ...the IGFBP-3 mRNA level in the kidney, the organ expressing ...
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Urinary [TIMP-2] × [IGFBP-7] for predicting acute kidney injury in patients undergoing orthotopic liver transplantation
... Furthermore, the small sample size in our study did not permit to reliably analyze whether other important risk factors such as MELD score, intraoperative blood loss, blood transfusion or fluid administration affected ...
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Common genetic variation in IGF1, IGFBP 1, and IGFBP 3 in relation to mammographic density: a cross sectional study
... The variant allele of rs1520220 in IGF1 was inversely associ- ated with mammographic density in the current study. In con- trast, the variant allele has been positively associated with circulating levels of IGF1 in ...
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Genetic and environmental components of interindividual variation in circulating levels of IGF I, IGF II, IGFBP 1, and IGFBP 3
... at 4 8 C, Europium-labeled IGF-II (2 ng/50 m l) was added to the wells and incubated for another 40 min at room ...icals), IGFBP-1 (16), IGFBP-3 (Celtrix Pharmaceuticals) and IG- FBP-2, -4, ...
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Vitreous levels of the insulin like growth factors I and II, and the insulin like growth factor binding proteins 2 and 3, increase in neovascular eye disease Studies in nondiabetic and diabetic subjects
... Retinal capillary nonperfusion results in neovascularization of the eye, which is restricted to the retina in less severe cases and progresses to the anterior chamber and the iris angle in the most advanced case, called ...
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Altered placental expression of PAPPA2 does not affect birth weight in mice
... QTL region, but are otherwise genetically homogeneous. The mRNA levels of β-actin in the placenta did not differ between genotypes (F (1,23) = 0.12, P = 0.73), indicating that this housekeeping gene was suitable for ...
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Investigation of β-Catenin-Mediated Regulation of IGFBP-6 and the Roles of IGFBP-6 and IGF-II in Dupuytren's Disease
... at 4°C and the pellet was resuspended into 1 ml ChIP Buffer (proprietary buffer included in the SimpleChIP Kit) supplemented with protease inhibitors and phenylmethylsulfonyl fluoride ...at 4°C to obtain ...
171
Investigation of insulin like growth factors/insulin like growth factor binding proteins regulation in metabolic syndrome patients
... of IGFBP-2, IGFBP-1, IGFBP-3, IGF-1, and IGF-2 in diabetic patients who were assigned to two groups: MSx diabetic and non-MSx diabetic ...of IGFBP-2 compared with healthy ...between ...
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