IL-1 beta
Human keratinocytes produce but do not process pro interleukin 1 (IL 1) beta Different strategies of IL 1 production and processing in monocytes and keratinocytes
... produce IL-1 alpha and beta mRNA in vitro, but only IL-1 alpha biological activity has been identified in keratinocyte ...of IL-1. Using several monoclonal antibodies to ...
7
Increased cyclic AMP levels enhance IL 1 alpha and IL 1 beta mRNA expression and protein production in human myelomonocytic cell lines and monocytes
... on IL-1 alpha and IL-1 beta mRNA expression and IL-1 production in human monocytes and nonlymphoid hematopoietic cell lines were ...express IL-1 ...of ...
10
Evaluation of anti-inflammatory and antioxidant effect of punicalagin (Pomegranate Extract) with scaling and root planing (SRP) and SRP alone on IL-1 beta and superoxide dismutase levels in patients with chronic periodontitis
... stimulus, IL-1 beta is thought to play a major role in the pathogenesis of periodontal ...diseases. IL-1 beta have been demonstrated at increased levels in inflamed gingival ...
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Atorvastatin attenuates the production of IL-1β, IL-6, and TNF-α in the hippocampus of an amyloid β1-42-induced rat model of Alzheimer’s disease
... IL-1 β , IL-6, and TNF- α proteins expressed in the brain tissue were detected by immunostaining, according to the standard streptavidin-biotin-peroxidase technique. Briefly, the paraffin ...
8
Succinate is an inflammatory signal that induces IL 1 beta through HIF 1 alpha
... Since both 2DG and αKG could inhibit HIF-1α accumulation and consequently induction of IL-1β, we hypothesized that the reported change in metabolism induced by LPS must be required for this response. We therefore ...
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Urinary excretion of IL-1β, IL-6 and IL-8 cytokines during relapse and remission of idiopathic nephrotic syndrome
... cytokines, IL-1 β , IL6 and IL8, using FlowCytomix kits (Bender Medsystems GmbH, Vienna, Austria), according to manufacturer’s instruc- ...were IL-1 β (4.2 pg/mL), IL-6 (1.2 pg/mL) and ...
5
The anti inflammatory cytokine, interleukin (IL) 10, blocks the inhibatory effect of IL 1 beta on long term potentiation a role for JNK
... l, 1 mg/ml) were added to sample buffer (10 l; Tris-HCl, ...(Promega; 1:4,000 in phosphate-buffered saline/Tween ...Biotechnology; 1:2,000 in PBS-T ...antibody; 1:10,000 dilution (Amersham ...
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Increased serum concentrations of IL 1 beta, IL 21 and Th17 cells in overweight patients with rheumatoid arthritis
... Obesity has recently been thought to be a chronic inflammation process. Adipose tissue is an endocrine/ paracrine organ and secretes pro-inflammatory cyto- kines. Adipose tissue also secretes adipokines, which have been ...
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Exacerbation of CNS inflammation and neurodegeneration by systemic LPS treatment is independent of circulating IL 1 beta and IL 6
... cytokines IL-1 b and IL-6 by approximately 80 and 90% ...Both IL-1b and IL-6 have been strongly associated with the induction of fever responses in rodents in response to systemic LPS ...
14
Rab39a binds caspase 1 and is required for caspase 1 dependent il 1{beta} secretion
... harvesting. IL-1β and TNF-α levels were measured by ...harvesting. IL-1β and TNF-α levels were measured by ...of IL-1β were measured by Real Time-PCR. Expression of IL-1β mRNA was normalized ...
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Antiallodynic and antihyperalgesic activities of zerumbone via the suppression of IL-1β, IL-6, and TNF-α in a mouse model of neuropathic pain
... morphine, 1 mg/kg ip, and amitriptyline, 20 mg/kg ip, that serve as positive controls, completely alleviated mechanical allodynia and showed mean values similar (p > ...
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Hif-1 alpha-Induced Expression of Il-1 beta Protects against Mycobacterial Infection in Zebrafish
... that Il-1b is a major proin- flammatory cytokine that would be upregulated by both mycobacterial infection and Hif-1a ...of il-1 b message after induction of inflammation via tailfin transection by ...
10
<p>Changes In Plasma NPY, IL-1β And Hypocretin In People Who Died By Suicide</p>
... persons. 1 The risk factors related to suicide include war, disaster, discrimination, abuse, violence, mental disorders, poor physical health and fi nancial ...
8
Serum IL-1β and IL-17 levels in patients with COPD: associations with clinical parameters
... and IL-17 are the key mediators of neutrophilic airway inflammation in ...serum IL-1β and IL-17 levels and associations between these two key mediators with clinical parameters in COPD ...serum ...
8
Functional profile of tissue infiltrating and circulating CD68+ cells in giant cell arteritis Evidence for two components of the disease
... synthesized IL-6-specific mRNA and produced IL-6 and IL-1 beta ...proteins. IL-6 and IL-1 beta production was not limited to CD68+ cells in the lymphoid ...
8
Alginate oligosaccharide indirectly affects toll-like receptor signaling via the inhibition of microRNA-29b in aneurysm patients after endovascular aortic repair
... ab31828), IL-1 beta (ab2105), IL-6 (ab6672), β -actin antibody (ab8227), and secondary antibody Goat Anti-Rabbit IgG H&L (HRP, ab6721) were purchased from Abcam (Beijing, ...Heights, ...
15
Mechanisms of stimulation of interleukin 1 beta and tumor necrosis factor alpha by Mycobacterium tuberculosis components
... and IL-1 beta proteins and mRNA from mononuclear phagocytes (THP-1 ...and IL-1 beta release by monoclonal antibodies to ...and IL-1 beta release with ...
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Biological properties of recombinant human monocyte derived interleukin 1 receptor antagonist
... specific IL-1 inhibitor that functions as a receptor antagonist ...Recombinant IL-1ra has 17,000 mol wt and binds to IL-1 receptors on T lymphocytes, synovial cells, and chondrocytes ...
5
Investigating the role of interleukin-1 beta and glutamate in inflammatory bowel disease and epilepsy using discovery browsing
... were: IL-1: 201 MEDLINE citations; IL-6: 216; IL-10: 71; IL-17: 19; IL-18: 14; IL-23: 4; and no citations retrieved for ...only IL-1 (mostly beta) and ...
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Effects of Escherichia coli hemolysin on human monocytes Cytocidal action and stimulation of interleukin 1 release
... interleukin 1 beta (IL-1 beta) from cultured ...monocytes. IL-1 beta release occurred in the presence of actinomycin D and cycloheximide, and was thus probably due ...
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