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IL-17

The IL 23/IL 17 axis in inflammation

The IL 23/IL 17 axis in inflammation

... (Th17/Th IL-17 ) that produce IL-17, IL-17F, IL-6, and TNF-a, but not IFN-g and ...blocking IL-23 or its downstream factors IL- 17 and IL-6, but not ...

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Disrupting the IL-36 and IL-23/IL-17 loop underlies the efficacy of calcipotriol and corticosteroid therapy for psoriasis

Disrupting the IL-36 and IL-23/IL-17 loop underlies the efficacy of calcipotriol and corticosteroid therapy for psoriasis

... the IL-23/IL-17 axis ...the IL-23/IL-17 inflamma- tory axis in Ald-induced mouse psoriatic ...the IL-23/IL-17 inflammatory axis in psoriasis and, ...

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IL 23 is essential for T cell–mediated colitis and promotes inflammation via IL 17 and IL 6

IL 23 is essential for T cell–mediated colitis and promotes inflammation via IL 17 and IL 6

... of IL-6 and IL-17. In order to better define the actions of IL-23, gene expression studies were performed to investigate the mechanism by which IL-23 induces colitis using the T cell ...

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Expression of Interleukin-17 associated with disease progression and liver fibrosis with hepatitis B virus infection: IL-17 in HBV infection

Expression of Interleukin-17 associated with disease progression and liver fibrosis with hepatitis B virus infection: IL-17 in HBV infection

... The IL-17 family of cytokines has been reported to be involved in many immune processes, most notably in inducing and media- ting proinflammatory ...(IL-1β), IL-6, and IL-23 (IL- ...

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IL 32 and IL 17 interact and have the potential to aggravate osteoclastogenesis in rheumatoid arthritis

IL 32 and IL 17 interact and have the potential to aggravate osteoclastogenesis in rheumatoid arthritis

... After isolation from whole blood, human PBMCs were incubated for 3 h. To remove nonadherent cells, the cul- tures were rinsed in medium. The adherent cells were cul- tured as osteoclast precursors using recombinant human ...

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Evidence of IL 17, IP 10, and IL 10 involvement in multiple organ dysfunction and IL 17 pathway in acute renal failure associated to Plasmodium falciparum malaria

Evidence of IL 17, IP 10, and IL 10 involvement in multiple organ dysfunction and IL 17 pathway in acute renal failure associated to Plasmodium falciparum malaria

... and IL-17 were significantly higher in the MOD than in the CM group, allowing for their differ- entiation (OR = ...and IL-17, respectively). Besides IL-17, high lev- els of ...

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Role of IL-17 in plaque psoriasis: therapeutic potential of ixekizumab

Role of IL-17 in plaque psoriasis: therapeutic potential of ixekizumab

... other IL-17 antagonists, ixekizumab achieved higher PASI 75 and PASI 90 response rates at week 12 and week 60 when dosed at 80 mg every 2 weeks through to week 12, followed by ixekizumab 80 mg every 4 weeks ...

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IL-17-differentiated macrophages secrete pro-inflammatory cytokines in response to oxidized low-density lipoprotein

IL-17-differentiated macrophages secrete pro-inflammatory cytokines in response to oxidized low-density lipoprotein

... with IL-17 contributed to the forma- tion of foam cells to the same extent as ...M1. IL-17 favors the capture of modified LDL [24] because it increases the expression of scavenger receptors ...

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Impact of Smoking on the IL-1Β, IL-8, IL-10, IL-17 and TNF-α Production in Chronic Periodontitis Patients

Impact of Smoking on the IL-1Β, IL-8, IL-10, IL-17 and TNF-α Production in Chronic Periodontitis Patients

... and progression rate of periodontal disease depends on complex interaction between periodonotopathic bacteria, cells of the host immune system and environmental factors (Page et al., 1997). These interactions are ...

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Relationship of redundant Th17 cells and IL-17A, but not IL-17 F, with the severity of obstructive sleep apnoea/hypopnoea syndrome (OSAHS)

Relationship of redundant Th17 cells and IL-17A, but not IL-17 F, with the severity of obstructive sleep apnoea/hypopnoea syndrome (OSAHS)

... including IL-17A and IL-17 F, and are broadly implicated in inflammatory and autoimmune diseases ...cytokines, IL-17A and IL-17 F, to OSAHS in ...

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Determination of il 17 and il 27 levels in sera of infertile women with unexplained infertility and polycystic ovary syndrome subjected to ovulation induction/intrauterine insemination program and their effects on pregnancy outcome

Determination of il 17 and il 27 levels in sera of infertile women with unexplained infertility and polycystic ovary syndrome subjected to ovulation induction/intrauterine insemination program and their effects on pregnancy outcome

... 2013). IL-17 induces the production of IL-1β which increases pro-inflammatory signaling during window of implantation (Aggarwal et ...2003). IL-17 induces the production of IL-6 ...

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Original Article IL-17 siRNA promotes human proliferation and osteogenic differentiation of human periodontal ligament stem cells via ERK1/2, JNK and p38 MAPK signaling

Original Article IL-17 siRNA promotes human proliferation and osteogenic differentiation of human periodontal ligament stem cells via ERK1/2, JNK and p38 MAPK signaling

... (IL)-17, IL-1β, IL-6, and signaling pathways such as mitogen-acti- vated protein kinases (MAPKs), extracellular signal-regulated protein kinase (ERK), Wnt, and nuclear factor (NF)-κB [5, 6, ...

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Elevated IL 17 levels in semi immune anaemic mice infected with Plasmodium berghei ANKA

Elevated IL 17 levels in semi immune anaemic mice infected with Plasmodium berghei ANKA

... From the data presented here it can concluded that cer- tain genes are contributing to the extent of survival (pro- tection) against Plasmodium infection through low Hb. And the mechanism employed in this protection ...

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Original Article Analysis of IL-6, IL-10, IL-17 levels in the blood of patients with chronic hepatitis B

Original Article Analysis of IL-6, IL-10, IL-17 levels in the blood of patients with chronic hepatitis B

... as IL-8 and IL-6, lead to rapid growth of mono- cytes and neutrophils, enhance local inflamma- tion and induce proinflammatory cytokines, thereby resulting in tissue ...that IL-17 in the serum ...

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Inflammation, cytokines, the IL-17/IL-6/STAT3/NF-κB axis, and tumorigenesis

Inflammation, cytokines, the IL-17/IL-6/STAT3/NF-κB axis, and tumorigenesis

... in 17 cases of human colon adenocarcinomas, 16 cases of human normal colon tissues adjacent to the resected colon adenocarcinomas, ten cases of human ulcerative colitis tissues from biopsies, and eight cases of ...

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Serum IL-1β and IL-17 levels in patients with COPD: associations with clinical parameters

Serum IL-1β and IL-17 levels in patients with COPD: associations with clinical parameters

... and IL-17 are the key mediators of neutrophilic airway inflammation in ...serum IL-1β and IL-17 levels and associations between these two key mediators with clinical parameters in COPD ...

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High expression of IL-17 and IL-17RE associate with poor prognosis of hepatocellular carcinoma

High expression of IL-17 and IL-17RE associate with poor prognosis of hepatocellular carcinoma

... of IL-6, -17RA, -22 and TNF-α in HCC than those in haemangioma, suggesting their potential value as monitoring indictors in ...and IL-17 can act in a synergistic manner to sustain neutrophil ...

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Evaluation of IL-4, IL-17, and IFN-γ Levels in PatientsWith Breast Cancer

Evaluation of IL-4, IL-17, and IFN-γ Levels in PatientsWith Breast Cancer

... IFN-γ, IL-17, and IL-4 concentrations were determined in tumor tissues, adjacent tissues of the tumor, and blood serum samples of these 2 groups of patients by enzyme-linked immunosorbent assay ...

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Increased expression of cardiac IL-17 after burn

Increased expression of cardiac IL-17 after burn

... of IL-17, 3 hours after injury as compared to the sham ...burn, IL-17 remained elevated, however, without significant differ- ence from the respective sham ...of IL-17 were ...

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Current perspectives on the role of IL-17 in autoimmune disease

Current perspectives on the role of IL-17 in autoimmune disease

... The introduction of biologicals for treatment of autoimmune disorders has dramati- cally changed the prognosis of these diseases. However, there are patients who are refractory to this treatment, and the frequency of ...

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