IL-1β
IL-1β mediates lung neutrophilia and IL-33 expression in a mouse model of viral-induced asthma exacerbation
... in IL-1 β was associated with reduced features of neutrophilic inflammation as well as a tendency towards reduced induction of TSLP gene expres- sion whereas IL-33 gene levels were significantly ...lung ...
10
Serum IL-1β can be a biomarker in children with severe persistent allergic rhinitis
... In the present study, we also investigated the chemokine ligand levels, that is, CCL11 (also known as eotaxin), and CCL24 (also known as eotaxin-2 or myeloid progenitor inhibitor factor-2), which are all epithelial ...
9
IL 1β dominates the promucin secretory cytokine profile in cystic fibrosis
... of IL-1 signaling in the SMGs could not be evaluated in our ...that IL-1α and IL-1β are constitutively expressed in SMGs (70), where MUC5B is basally produced, and an important future question ...
19
Original Article Resveratrol inhibits IL-1β, IL-18, and ICAM-1 in a nasopharyngeal carcinoma model
... In this experiment, a nude mice model of naso- pharyngeal carcinoma was established, exam- ining the effects of RES on IL-1β, IL-18, and ICAM-1 in nasopharyngeal carcinoma. There were some ...
8
Nlrp3-dependent IL-1β inhibits CD103+ dendritic cell differentiation in the gut
... of IL-1, but not of IL-18, levels (20). The activation of both IL-1β and IL-18 requires inflammasomes and caspase-1, with NLRP3 and NLRP6 as the best-characterized ...NLRP3-dependent ...
15
Evaluation of the Role of Herpes Simplex Virus Type 1 in the Secretion of Interleukin-1β (IL-1β) by Cultured Gingival Epithelial Cells
... functional, IL-1β needs to be cleaved by caspase 1 (8) that is activated via intracellular macromolecules called inflammasomes ...secret IL- 1βthrough activation of NALP3 after initial stimulation by ...
5
Decreased IL-8 levels in CSF and serum of AD patients and negative correlation of MMSE and IL-1β
... cytokine IL-1β is believed to drive the neuroinflammatory process and has been dem- onstrated to be upregulated in AD and other neurode- generative disorders [14, 18, ...serum IL-1β levels in ...
8
Hydroxychloroquine inhibits IL 1β production from amyloid stimulated human neutrophils
... Recent evidence suggests that the inflammasome is dys- regulated in SLE and plays an important role in lupus- associated organ damage [9]. For example, NLRP3 inflam- masome contributes to glomerular injuries and ...
9
Original Article Serum levels of TNF-α, IL-1β, IL-9, and IL-15 in acute respiratory distress syndrome
... reactions. IL-1β can promote the inflamma- tory cascade reactions in ARDS progression [13], induce the nitric oxide synthase genera- tion [11] and work with cytokines TNF-α, IL-6, and IL-8 to ...
8
Differential expression of P2X7 receptor and IL-1β in nociceptive and neuropathic pain
... Peripheral blood was collected from patients and healthy volunteers between 9:00 and 9:30 AM. Samples were assessed for differential leukocyte count by routine labora- tory testing. For cytokine assessment, blood was ...
9
Role of P2X7 Receptors in Release of IL-1β: A Possible Mediator of Pulmonary Inflammation
... of IL-1 has been investigated and proposed in a model by Surprenant et ...model IL-1β is packaged into small plasma membrane blebs (microvesicles) which are released into the extracellular ...mature ...
6
IL-1β induces rod degeneration through the disruption of retinal glutamate homeostasis
... on IL-1β- ...secondary IL-1β-dependent rod degeneration ...that IL-1β- and hMo-induced rod degenerations result from non-NMDA ionotropic receptor over- ...
12
Antipsoriatic and Inhibitory effects of an oral dosage form containing Bioflavonoids on inflammatory cytokines IL-1α, IL-1β, IL-6, IL-8, IL-17 and TNF-α
... plemented RPMI-1640 media at a concentration of 3 µg/ml. The test sample was dissolved in DMSO at concentrations of 1, 3, 10, and 30 µg/ml and each of these concentrations was diluted with the supplemented RPMI-1640 ...
10
IL-1β impairs retrograde flow of BDNF signaling by attenuating endosome trafficking
... which IL-1β affects the trafficking of the BDNF endosomal signaling complex ...which IL-1β affects BDNF endosome ...that IL-1β treat- ment was associated with a ...between ...
12
ENTPD 1 disrupts inflammasome IL 1β–driven venous thrombosis
... and IL-1β release in CD39-deficient ...an IL-1β–neutralizing antibody or the IL-1 receptor inhibitor anakinra attenuated the thrombosis risk in CD39-deficient ...that ...
7
LPS-induced release of IL-6 from glia modulates production of IL-1β in a JAK2-dependent manner
... changes. First, we confirmed that incubation of glia in the presence of LPS for 2 h increased JAK2 (upper panel; Figure 2A) and STAT1 (middle panel; Figure 2A) phosphorylation. Interaction of JAK proteins with their ...
10
Joint production of IL 22 participates in the initial phase of antigen induced arthritis through IL 1β production
... of IL-1β was also observed in other models of articular ...that IL-1β mediates inflammation and dysfunction of the joint induced by the injection of monosodium urate (MSU) crystals into the ...
13
The circadian clock protein BMAL1 regulates IL 1β in macrophages via NRF2
... (112). IL-‐1β, and IL-‐18 are released from the lysed cells, propagating the inflammatory response in a cascade like fashion (110, 113) (Figure ...
219
The Correlation Between IL-1β and IL-10 Levels in Estimating The Risk of Febrile Seizures
... fact, IL-10 inhibits the release of pro-inflammatory media- tors from monocytes/ macrophages, and there- fore inhibits the LPS- and IFN-γ-induced secre- tion of TNF- α , IL-1β, IL-6, ...
6
Bioluminescence imaging for IL-1β expression in experimental colitis
... of IL-1β production (luciferase ex- pression) in the abdominal region of cHS4I-hIL-1βP-Luc transgenic mice were determined at day ...0. IL-1β (lucife- rase expression) production was ...
6