IL-37
Evaluating Serum Levels of IL-33, IL-36, IL-37 and Gene Expression of IL-37 in Patients with Psoriasis Vulgaris
... of IL-36/IL-37, we may conclude involvement of such cytokines in the modification of inflammation in ...that IL-37 inhibits inflammatory reactions in autoimmune diseases in which it is ...
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<p>IL-37 promotes cell apoptosis in cervical cancer involving Bim upregulation</p>
... sion IL-37 group, the apoptosis rates of the IL-37 +SiBim group reduced 31% and ...the IL-37-induced apoptosis, but it was con fi rmed that Bim was one of ...that ...
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IL 37 inhibits the production of inflammatory cytokines in peripheral blood mononuclear cells of patients with systemic lupus erythematosus: its correlation with disease activity
... TNF-α, IL-1β, IL-6 and IL-10 were significantly increased in PBMCs of SLE patients than in PBMCs from healthy ...of IL-37 was correlated with the activity of disease in ...inhibitor ...
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Original Article CD4 CD25 Foxp3 regulated T cells and expression of IL-37 and chemokine ligand 2 in lung cancer and their clinical significance
... 27]. IL-37 is an anti-inflammatory cytokine with several biological functions and acts through an intracellular mechanism translocat- ing to the nucleus ...of IL-37 in epithelial cells or ...
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Original Article Hsa-miR-921 mediates lung injury via IL-37 in a rat model of traumatic hemorrhagic shock
... THS is one of the most serious and life-threat- ening complications in clinical settings. It may cause irreversible injury despite immediate fluid resuscitation, and it can result in death [1-3]. ALI is a common ...
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Original Article Protective mechanism of IL-37 in the regulation of Tregs in myocardial ischemia microcirculation reperfusion injury
... Abstract: IL-37 is a newly discovered natural inflammatory inhibitor in recent ...of IL- 37 in the inflammatory reaction of atherosclerosis in patients with coronary artery disease may be ...
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IL-37 Suppresses MyD88-mediated Inflammatory Responses in Human Aortic Valve Interstitial Cells
... that IL-37 suppresses human AVIC inflammatory responses to Toll-like receptor (TLR) ...molecule-1, IL-6, IL-8 and monocyte chemoattractant ...stimulation. IL-37 reduced ...
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<p>IL-37 induces anti-tumor immunity by indirectly promoting dendritic cell recruitment and activation in hepatocellular carcinoma</p>
... of IL-37 was posi- tively associated with the degree of CD1a + DCs in fi ltration in 155 HCC patients, and the IL-37 high DC high patients were found to have the best ...that ...
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Weidlich, Simon (2017): Expression of Interleukin-37 in paediatric chronic inflammatory bowel disease. Dissertation, LMU München: Medizinische Fakultät
... against IL-37 by using the same polyclonal goat anti IL-37 Ab as used for this work and found a similar expression pattern of ...of IL-37 than healthy ...
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Interleukin-37 suppresses tumor growth through inhibition of angiogenesis in non-small cell lung cancer
... Results: IL-37 mRNA and protein expressions were significantly decreased in NSCLC tissues, and decreased intratumoral IL-37 expression was significantly associated with tumor state, TNM stage ...
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Interleukin 37 limits monosodium urate crystal induced innate immune responses in human and murine models of gout
... human IL-37 (rhIL-37) in human and murine gout ...of IL-37 in patients with active and inactive gouty arthritis and assessed the effect of rhIL-37 in human and murine gout ...
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Development of Electrochemical Immunosensor for the Detection of Human interleukin-37 for Potential Diabetes Diagnosis
... of IL-37 at rest [7, 8] and exercise [9] stem from adipose tissue and skeletal muscle, respectively, while main site of clearing IL- 37 was splanchnic ...of IL-37, which is ...
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Original Article Downregulated interleukin 37 expression associated with aggravation of intervertebral disc degeneration
... Interleukin 37 (IL-37) is an anti-inflammatory cytokine which was proven to be associated with several dis- eases characterized with ...little IL-37 related knowledge in IVDD up to ...
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Original Article Effects of interleukin-37 on cardiac function after myocardial infarction in mice
... (TNFα), IL-1β, and IL-18 can up-regulate IL-37 expression ...that IL-37 exhibits anti-inflammatory effect in sepsis and liver ischemia-reperfusion model ...that ...
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The potential of interleukin-37 as an effective therapeutic agent in asthma
... that IL-37 has profound immunoregula- tory functions ...1). IL-37 is a member of the IL-1 cytokine family that binds to IL-18Rα, which prevents it from binding IL-18 ...
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<p>Plasma Interleukin-37 is Elevated in Acute Ischemic Stroke Patients and Probably Associated With 3-month Functional Prognosis </p>
... plasma IL-37 levels are asso- ciated with unfavourable outcomes at 3 months after AIS, which is consistent with the observation that increased IL-37 levels correlate with a poor prognosis of ...
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Interleukin 37 is increased in ankylosing spondylitis patients and associated with disease activity
... induce IL-37 expression in PBMCs from healthy controls [22], indicating TNF-α as one of inducers involved in the up-regulation of IL-37 in ...of IL-6 and Th17 responses, which reflects ...
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Increased miR-223-3p in Leukocytes Positively Correlated with IL-17A in Plasma of Asthmatic Patients
... IFN-γ, IL-4, and IL-17A, respectively. The expression levels of IFN-γ, IL-4, and IL-17A in plasma from healthy controls and asthmatic patients were detected using ELISA kits following the ...
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Genetic polymorphisms and their involvement in the regulation of the inflammatory response in asthma and COPD
... Asthma and COPD are lung diseases, which represent a major public health problem and our country is no ex- ception. Both disease entities share a common mechanism to inflammation, which acts differently in both patholo- ...
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In vitro secretion profiles of interleukin (IL)-1beta, IL-6, IL-8, IL-10, and TNF alpha after selective infection with Escherichia coli in human fetal membranes
... the lower chamber by amniotic tissue, which allowed test- ing the two compartments independently (Figure 1). A detailed description and validation of this model has been published previously [13]. One milliliter of DMEM ...
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