IL-6, interleukin-6
The involvement of proinflammatory cytokines in diabetic nephropathy: Focus on interleukin 1 (IL-1), interleukin 6 (IL-6), and tumor necrosis factor-alpha (TNF-α) signaling mechanism
... About 20-40% of type 2 diabetic patients may develop diabetic nephropathy (DN) as its complication. The pathogenesis of DN is complex. Classically, metabolic and hemodynamic impairment are considered as its pathogenesis. ...
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The effect of novel polymorphisms in the interleukin 6 (IL 6) gene on IL 6 transcription and plasma IL 6 levels, and an association with systemic onset juvenile chronic arthritis
... rum interleukin-6 (IL-6) that parallels the classic quotidian ...of IL-6 expression, we examined the 5 9 flanking region of the IL-6 gene for ...or IL-1, ...
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Influence of interleukin-6 and G174C polymorphism in IL-6 gene on obesity and energy balance
... as IL-1, IL-6, and ...that IL-6 plays a role in lipid metabolism and energy ...of IL-6 gene af- fects the level of interleukin-6 expression and, conse- ...
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Serum soluble interleukin 6 (IL 6) receptor and IL 6/soluble IL 6 receptor complex in systemic juvenile rheumatoid arthritis
... human IL-6 receptor (sIL-6 R) levels were measured in the sera of 20 healthy children and of 25 patients with systemic juvenile rheumatoid arthritis ...serum IL-6 levels measured with ...
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Immunotherapy of brain metastases: breaking a “dogma”
... factor-1; IL: Interleukin; IL-10: Interleukin-10; IL-1 β : Interleukin-1 β ; IL- 23: Interleukin-23; IL-6: Interleukin-6; IL-8: ...
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Anti inflammatory activity of monogalactosyldiacylglycerol in human articular cartilage in vitro: activation of an anti inflammatory cyclooxygenase 2 (COX 2) pathway
... on IL-1 a (interleukin-1alpha) treated ...U/ml IL-1a (Interleukin-1alpha) and/or 200 U/ml TNFa (Tumor Necrosis Factor alpha) for 24 ...with IL-6 (Interleukin-6), ...
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Reactive Hyperemia and Interleukin 6, Interleukin 8, and Tumor Necrosis Factor-α in the Diagnosis of Early-Onset Neonatal Sepsis
... TNF-␣, IL-6, IL-8, and CRP levels were measured with a chemiluminescence immu- noassay (Immulite; Diagnostic Products Corporation, Los Ange- les, ...for IL-6 was 5.0 pg/mL, for ...
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Molecular changes indicative of cartilage degeneration and osteoarthritis development in patients with anterior cruciate ligament injury
... cytokines interleukin-1 β (IL-1 β ) and interleukin-6 (IL-6) and degrading enzyme matrix metalloproteinase 13 (MMP-13), all indicative of cartilage degeneration and ...
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Original Article Effects of glutamine on alveolar epithelial barrier function after cardiopulmonary bypass
... (RI), interleukin-6 (IL-6), interleukin-10 (IL-10), tumornecrosisfactor-α (TNF-α), lipopolysaccharide (LPS), matrix metalloprotein-9 (MMP-9), extravascular lung water (EVLW), ...
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The efficacy and safety of anti-interleukin-6 receptor monoclonal blockade in a renal transplant patient with Castleman disease: early post-transplant outcome
... A 33-year-old man visited an outpatient clinic with haematuria and proteinuria. One year later, the patient was diagnosed with IgA nephropathy by a renal biopsy and was treated with diet and medication. At 36 years of ...
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Myeloid-related protein 8/14 complex describes microcirculatory alterations in patients with type 2 diabetes and nephropathy
... of Interleukin-6 (IL-6) and TNF-α with proteinuria and retinal artery caliber in patients with type 2 diabe- tes and nephropathy: A) IL-6 and proteinuria, B) IL-6 ...
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Effect of Helicobacter pylori infection on chronic periodontitis by the change of microecology and inflammation
... as interleukin 6 (IL-6), interleukin 8 (IL-8), tumor necrosis factor alpha (TNF-α) and interferon gamma (IFN-γ) could be produced by immunocytes in inflammatory ...of IL-8 ...
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Ethanolic extract of propolis inhibits atherosclerosis in ApoE-knockout mice
... Serum interleukin-6 (IL-6), interleukin-17 (IL-17), endothelin (ET), inducible nitric oxide synthase (iNOS) and vascular endothelial growth factor (VEGF) were determined with ...
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A common functional variant on the pro-inflammatory Interleukin-6 gene may modify the association between long-term PM10 exposure and diabetes
... plasma IL-6 concentrations in our participants due to lack of funds, precluding our assessment of association between candi- date SNPs and serum IL-6 levels, but there was a positive ...
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Lymphocytes influence intracranial aneurysm formation and rupture: role of extracellular matrix remodeling and phenotypic modulation of vascular smooth muscle cells
... Ongoing work to elucidate the mechanisms behind IA pathogenesis promises to provide new targets for the diagnosis and treatment of this disease. Current under- standing characterizes IA as a chronic inflammatory dis- ...
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Differential expression of pro inflammatory cytokines IL 15Ralpha, IL 15, IL 6 and TNFalpha in synovial fluid from Rheumatoid arthritis patients
... cytokines interleukin 1 (IL1), tumour ne- crosis factor alpha (TNFalpha), and interleukin 6 (IL6), in particular, have been identified and intra-articular as well as systemic levels of these ...
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Systemic and Other System Disorders
... This study was conducted to compare the levels of circulating plasma interleukin-6 (IL-6), spontaneously produced IL-6, and IL-6 mRNA in HIV-infected donors with the levels in healthy co[r] ...
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Simvastatin nanoparticles attenuated intestinal ischemia/reperfusion injury by downregulating BMP4/COX-2 pathway in rats
... of interleukin-4 (IL-4), interleukin-6 (IL-6), interleukin-10 (IL-10), tumor necrosis factor-α, and nitric oxide (NO) were checked, and the dry/wet intestine ...
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Assessment of Pro-Inflammatory Cytokines Level in Stored Blood for Transfusion in Port Harcourt, Nigeria
... as interleukin-4(IL-4), interleukin 6(IL-6) and tumor necrosis factor alpha (TNF-α) in order to know the extent to which stored blood could become potentially dangerous to ...– ...
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TGF-β pathway activation by idiopathic pulmonary fibrosis (IPF) fibroblast derived soluble factors is mediated by IL-6 trans-signaling
... TGFβ is extensively involved in the development of fi- brosis in different organs [13, 31, 42], with the interplay between STAT3 and TGF-β pathways is widely dis- cussed. For instance, targeting of JAK-2 in SSc fibro- ...
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