imaging-guided tumor therapy
<p>Multifunctional hypoxia imaging nanoparticles: multifunctional tumor imaging and related guided tumor therapy</p>
... Precise tumor therapy requires technological progress in tumor imaging and ...whole tumor genesis, growth, metastasis, and inva- siveness ...in tumor areas can greatly contribute ...
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Rod-shape MSN@MoS2 Nanoplatform for FL/MSOT/CT Imaging-Guided Photothermal and Photodynamic Therapy
... were hemocompatible and could be administered intravenous injection for in vivo anti-tumor treatment (Figure S7). The HSA encapsulation might offer the nanoparticles good biocompatibility [38]. To verified the ...
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Red blood cell membrane-enveloped O2 self-supplementing biomimetic nanoparticles for tumor imaging-guided enhanced sonodynamic therapy
... Artificial materials often trigger an immune response from the body’s immune defense system and, therefore necessitate stringent requirements during application in vivo. Inspired by the long circulation, good ...
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MR Imaging Guided Interstitial Photodynamic Laser Therapy for Advanced Head and Neck Tumors
... Patients with significant recurrent disease were sequentially recruited over 4 years from the multidisciplinary head and neck cancer clinic of our institution, a tertiary referral center. The Table summarizes the ...
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Biomineralized Bimetallic Oxide Nanotheranostics for Multimodal Imaging-Guided Combination Therapy
... DMEM medium was added. Following the 12 h period, the cells were rinsed thoroughly with PBS, and then treated with 0.5 mL trypsin. The harvested cells were suspended in PBS and centrifuged (2500 rpm, 5 min). ...
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Magnetic Resonance Imaging-Guided Adaptive Radiation Therapy: A "Game Changer" for Prostate Treatment?
... assessing imaging changes during and directly after treatment is available; how- ever, studies have shown that the apparent diffusion coefficient values from DWI increase after treatment (43-45), with the greatest ...
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Imaging Key Biomarkers of Tumor Angiogenesis
... whether imaging with these molecular tracers would be able to compete with MRI, CT, or metabolic PET imaging in detection and staging of primary tumors and meta- static ...molecular imaging for ...
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Fabrication of Red Blood Cell-Based Multimodal Theranostic Probes for Second Near-Infrared Window Fluorescence Imaging-Guided Tumor Surgery and Photodynamic Therapy
... the tumor, suggesting that ICG might not be directly applicable for clinical image-guided tumor surgery (Figure ...the tumor retention kinetics of NIR II nanoprobes in a favorable manner, in ...
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Artesunate Loaded and Near Infrared Dye Conjugated Albumin Nanoparticles as High Efficiency Tumor Targeted Photo Chemo Theranostic Agent
... fluorescence imaging agent and phototherapy agent due to its PTT-PDT prop- ...chemotherapy. Guided by the NIR imaging results, the high effect of the targeted IGPC combination was demonstrated both ...
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Degradable Hollow Mesoporous Silicon/Carbon Nanoparticles for Photoacoustic Imaging-Guided Highly Effective Chemo-Thermal Tumor Therapy in Vitro and in Vivo
... the tumor (shown in red dotted circle) growth and achieve complete tumor ...the tumor growth, their therapeutic efficacies are much lower than that of the combinational chemo-PTT ...100% tumor ...
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Strategies for Image-Guided Therapy, Surgery, and Drug Delivery Using Photoacoustic Imaging
... Neuschmelting et al. evaluated both 2D and 3D handheld MSOT (multispectral optoacoustic tomogr- aphy) devices developed by iThera Medical by imaging murine brain melanomas at 4 MHz and 700 – 900 nm [91]. The ...
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Nanoliposomes Co-Encapsulating CT Imaging Contrast Agent and Photosensitizer for Enhanced, Imaging Guided Photodynamic Therapy of Cancer
... inhibited tumor growth in vivo under LED irradiation as a result of the iodine-enhanced PDT combined with photothermal therapy ...CT imaging capability of reported iodinated nanoplatforms for PDT is ...
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Focal low-dose rate brachytherapy for the treatment of prostate cancer
... in imaging techniques as well as tissue sampling will help identify patients appropriate for focal therapy, other factors may need to be ...and tumor stage (#T2b) (Table ...
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Bubble-Manipulated Local Drug Release from a Smart Thermosensitive Cerasome for Dual-Mode Imaging Guided Tumor Chemo-Photothermal Therapy
... partial tumor inhibition, which should be due to the limited tumor accumulation of free DOX and the slow drug release rate of DOX-DiR@cerasome (ABC) without laser irradiation, ...high tumor ...
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Active Tumor Permeation and Uptake of Surface Charge-Switchable Theranostic Nanoparticles for Imaging-Guided Photothermal/Chemo Combinatorial Therapy
... have emerged [19-25]. Wang and co-workers devel- oped a 2,3-dimethylmaleic anhydride (DMA)- modified nanogel with tumor acidity-activated charge conversion ability as a doxorubicin (DOX) carrier [19]. Through the ...
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Magnetic resonance-guided regional gene delivery strategy using a tumor stroma-permeable nanocarrier for pancreatic cancer
... Gene therapy is a very promising technology for treatment of pancreatic ductal adenocarcinoma ...the tumor stroma and explore an imaging-guided local gene delivery strategy for PDAC to promote ...
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Photosensitizer Loaded Nano-Graphene for Multimodality Imaging Guided Tumor Photodynamic Therapy
... Photodynamic therapy (PDT) is an FDA ap- proved modality for the local treatment of a variety of oncological, cardiovascular, dermatological, and ophthalmic diseases ...improved tumor specific killing ...
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Design of Tumor Acidity-Responsive Sheddable Nanoparticles for Fluorescence/Magnetic Resonance Imaging-Guided Photodynamic Therapy
... the tumor tissue, resulting in improved cell uptake, enlarged MR signal intensity, rapid release of Ce6 within tumor cells, and elevated PDT ...that tumor-acidity-responsive nanoparticles with fine ...
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In vivo Imaging-Guided Nanoplatform for Tumor Targeting Delivery and Combined Chemo-, Gene- and Photothermal Therapy
... by tumor cell through receptor-mediated endocytosis, DOX release and db-DNA dissociation were simultaneously triggered to induce apoptosis and inhibit tumor ...
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Prediction of Tumor Recurrence and Therapy Monitoring Using Ultrasound-Guided Photoacoustic Imaging
... oxygenated and deoxygenated hemoglobin signal as described by Needles et al [26]. At these wavelengths, the absorbance of BPD is minimal (Fig. 1A). PAI was performed using pulsed nanosecond laser (10 ns pulse width) ...
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