Immediate early gene
Repression of adenovirus early gene expression by coinfection with a temperature-sensitive mutant in the immediate-early gene of pseudorabies virus.
... Our approach was to coinfect cells at the nonpermissive temperature with wild-type adenovirus and a temperature-sensitive mutant in the immediate-early gene of either pseudorabies virus [r] ...
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CNS axon regeneration inhibitors stimulate an immediate early gene response via MAP kinase-SRF signaling
... of gene expression. We focused on SRF (serum response factor), a gene regulator mediat- ing an immediate early gene (IEG) response of ...cytoskeletal gene abundance ...
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Variations in the cytomegalovirus major immediate early gene found by direct genomic sequencing
... An assay to detect and sequence DNA from human cytomegalovirus HCMV immediate-early gene region 1 has been developed; it involves in vitro amplification by the polymerase chain reaction [r] ...
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SRF activation in immediate early gene transcription
... in immediate early gene activation (Treisman, 1994) were used to determine the downstream signalling requirements for different ...reporter gene was unaffected, and LPA induction was reduced ...
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Structure and expression of murine cytomegalovirus immediate-early gene 2.
... Regulated expression of early and late RNAs and proteins from the human cytomegalovirus immediate-early gene region.. Promoter-specific trans activation and repression by human cytomegal[r] ...
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The Major Immediate-Early Gene ie3 of Mouse Cytomegalovirus Is Essential for Viral Growth
... major immediate-early gene ie3 of mouse cytomegalovirus (MCMV) and that of the corresponding ie2 gene of human cytomegalovirus to viral replication are not ...major ...
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The Human Cytomegalovirus Major Immediate-Early Enhancer Determines the Efficiency of Immediate-Early Gene Transcription and Viral Replication in Permissive Cells at Low Multiplicity of Infection
... on early viral gene ...on early viral gene expres- sion, we examined the recombinant viruses with the UL127 promoter driving the expression of ...
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Regulation of a human cytomegalovirus immediate-early gene (US3) by a silencer-enhancer combination.
... taining DNA region, then those complexes should be detect- able at all times except during maximal transcription from the US3 gene. To test this hypothesis, nuclear extracts were pre- pared from either mock- or ...
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Nuclear localization and transcriptional activation activities of truncated versions of the immediate-early gene product of equine herpesvirus 1.
... alphaherpesvirus gene regulation (9, 15, 23, 24, 29–31, 35). The immediate-early (IE) gene product of EHV-1 (also referred to as the IR1 gene product) shows significant homology to a ...
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Sequence and structural organization of murine cytomegalovirus immediate-early gene 1.
... In this paper we present the physical organization, as well as the deduced amino acid sequence and secondary structure, of pp89 and the complete nucleotide sequence of iel.. The relation[r] ...
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Cellular Antisilencing Elements Support Transgene Expression from Herpes Simplex Virus Vectors in the Absence of Immediate Early Gene Expression
... LAT gene, is flanked by at least one of these sites (8, ...LAT gene, including key splicing signals for the formation of the stable LAT introns ...viral gene expression in latency compared to the ...
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Structural analysis of the major immediate early gene of human cytomegalovirus.
... The sequence of the gene as well as the sequences at the splice junctions permitted us to deduce the structure of the mRNA molecule and its corresponding Human cytomegalovirus CMV, like [r] ...
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The Human Cytomegalovirus Major Immediate-Early Distal Enhancer Region Is Required for Efficient Viral Replication and Immediate-Early Gene Expression
... major immediate-early (MIE) genes, encoding IE1 p72 and IE2 p86, are activated by a complex enhancer region (base positions -65 to -550) that operates in a cell type- and differentiation-dependent ...the ...
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Autoregulation of the human cytomegalovirus major immediate-early gene.
... STINSKI* Department of Microbiology, School of Medicine, University of Iowa, Iowa City, Iowa 52242 Received 6 May 1985/Accepted 1 August 1985 Infection of permissive cells with either he[r] ...
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An early gene maps within and is 3' coterminal with the immediate-early gene of equine herpesvirus 1.
... The 4.4-kb E mRNA IR2 was shown by Northern blot analysis to i map within the EHV-1 inverted repeat sequences that encode the IE mRNA, ii be transcribed in the same direction as the IE m[r] ...
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Regulated expression of early and late RNAs and proteins from the human cytomegalovirus immediate-early gene region.
... 2699 Downloaded from http://jvi.asm.org/ on November 10, 2019 by guest Expression of RNA and protein from the human cytomegalovirus immediate-early IE gene region map units 0.732 to 0.75[r] ...
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Characterization of the regulatory functions of the equine herpesvirus 1 immediate-early gene product.
... These experiments demonstrated that i the EHV-1 IE gene product is a bifunctional protein capable of both positive and negative modulation of gene expression; ii the IE gene product poss[r] ...
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Cellular RNA Helicase DHX9 Interacts with the Essential Epstein-Barr Virus (EBV) Protein SM and Restricts EBV Lytic Replication
... lytic gene expression and ...EBV immediate early (IE) or early (E) gene expression was enhanced by DHX9 depletion and was contributing to the increase in viral infectious particles, we ...
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Comparison of the Complete DNA Sequences of the Oka Varicella Vaccine and Its Parental Virus
... in gene 62, located within the IRS region (or in gene 71 located within the TRS region) and its flanking regions, although no mutations were found in genes encoding other transactivators, such as genes 4, ...
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Genome-Wide Histone Acetylation Profiling of Herpesvirus saimiri in Human T Cells upon Induction with a Histone Deacetylase Inhibitor
... the immediate-early gene car- ried on ...delayed-early gene orf6, which displays homology to a single-stranded DNA (ssDNA) binding protein ...with immediate-early kinetics ...
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