Immune homeostasis
Ndfip1 Regulates The Identity And Pathogenicity Of Th17 And Treg Cells To Promote Normal Immune Homeostasis
... the immune system must recruit cells with effector responses that are appropriate for the task at ...normal immune homeostasis in the face of constantly changing microbes in the ...
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Role of Microbial Flora and Probiotics in Host Immune Homeostasis
... host immune homeostasis as well as the concept of ‘probiotics’ as a possible therapeutic approach to restore the normal gut microbial flora and host immune ...
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Loss of immune homeostasis dictates SHIV rebound after stem-cell transplantation
... Microbial translocation markers correlate with VL rebound. We screened serum samples for a panel of mark- ers of microbial translocation, as myeloablative conditioning can trigger gut damage and microbial translo- cation ...
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Pediatric Inflammatory Bowel Disease: A Review of Immune Homeostasis and Genetics with an Emphasis on the IL-10 Pathway
... The available evidence supports the growing belief that EO- IBD is determined largely by genetics. Most of these genes are implicated in the immune regulation. The IL-10/STAT3 pathway is a well-studied gene ...
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Single cell RNA sequencing reveals T helper cells synthesizing steroids de novo to contribute to immune homeostasis
... of immune induction from mucosal tissues, such as in the lung and intestine, has been shown to play a tolerogenic role to maintain tissue homeostasis (Cima et ...ated immune response during ...
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MerTK mediates immune homeostasis: effects upon dendritic cell function and Type 1 diabetes
... In humans and mice DC are identified by expression of the cell-surface marker CD11c. DC are further differentiated into conventional DC (cDC) and plasmacytoid DC (pDC). Murine cDC consist of CD11c + CD11b + CD8α - and ...
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IL-10 control of CD11c myeloid cells is essential to maintain immune homeostasis in the small and large intestine
... signaling develop severe colitis, which cannot be rescued by exogenous IL-10 [33]. Colitis was associated with perturbed Treg cell generation attributed to defective anti- inflammatory macrophage function. In addition, ...
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The regulation of T cell homeostasis and autoimmunity by T cell–derived LIGHT
... Costimulatory molecules on antigen-presenting cells (APCs) play an important role in T cell activation and expansion. However, little is known about the surface molecules involved in direct T-T cell inter- action ...
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PubMedCentral-PMC5728448.pdf
... lymphocytes, whereas C56BL/6J mice had an average frequency of 36.96% and BALB/cJ had an average frequency of 46.4% (Fig. 1A). Within these splenic CD3+ T cell populations, we further examined the frequencies of CD8+ T ...
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B cell, CD8 + T cell and gamma delta T cell infiltration alters alveolar immune cell homeostasis in HIV infected Malawian adults
... of immune cell populations in the lung. Disruption in immune homeostasis has been shown to lead to increased susceptibility to both infectious and non-infectious ...of immune cell populations ...
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Commensal Clostridia: leading players in the maintenance of gut homeostasis
... to immune homeostasis in the intestine is an important question to ...enforce immune tolerance towards commensal ...for immune homeostasis, contributing to the suppression of ...
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Identifying USPs regulating immune signals in Drosophila: USP2 deubiquitinates Imd and promotes its degradation by interacting with the proteasome
... of immune signals by ubiquitin-dependent mechanisms prompted us to identify other ubiquitin specific prote- ases (USPs) acting in Imd and Toll dependent immune ...of immune signalling in vivo ...
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Role of Micrornas on Immune System Components in Physiological and Pathophysiological Gut Micro Milieu
... of immune system suppress its anti-cancer responses leading to bypass its immune surveillance and promoting cancer ...of immune cells through a myriad of aberrant biochemical mechanisms including the ...
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Gliotoxin Suppresses Macrophage Immune Function by Subverting Phosphatidylinositol 3,4,5 Trisphosphate Homeostasis
... in immune cells, it is helpful to recall that this is a small, membrane-permeant molecule (12, 49, 50) whose toxicity entirely depends on its bridged disul- fide ring (11, ...
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Vahl, Johann Christoph (2013): TCR signals in the identity and function of mature NKT and regulatory T cells. Dissertation, LMU München: Fakultät für Chemie und Pharmazie
... transient immune activation caused by the poly(I:C) administration contributes to the observed ...significant immune activation, not to mention loss of CD1d- expressing antigen-presenting B cells and ...
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Effects of continuous renal replacement therapy on renal inflammatory cytokines during extracorporeal membrane oxygenation in a porcine model
... The present study showed that inflammatory cytokines including IL-1β, IL-6, TNF-α, NF-КB significantly in- creased in the ECMO group, and further confirmed re- sult that it can be evoked by ECMO-related SIRS when ECMO ...
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Dual epithelial and immune cell function of Dvl1 regulates gut microbiota composition and intestinal homeostasis
... Homeostasis of the gastrointestinal (GI) tract is regulated by interactions between constituents of the intestinal ecosystem, including epithelial and immune cell populations and the resident microbiota. ...
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Manganese Homeostasis in Group A Streptococcus Is Critical for Resistance to Oxidative Stress and Virulence
... innate immune cells, such as neutrophils and macrophages, mobilize to the site of in- fection, to control GAS by phagocytosis ...innate immune system can use zinc as an antimicrobial ...iron ...
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The conceptualisation of health and disease in veterinary medicine
... Homeopathic health definitions were stated to be 'holis- tic' and were mainly based on the idea that health is depending on homeostasis. However, as health definition of conventional veterinary textbooks also ...
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Immune cells control skin lymphatic electrolyte homeostasis and blood pressure
... Blocking this MPS-driven regulatory process leads to reduced cutaneous lymphatic capillary density, skin electrolyte accumulation, reduced eNOS expression in blood vessels, and increased[r] ...
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