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Immunodeficiency diseases

Effects of family history and consanguinity in primary immunodeficiency diseases in children in Qatar

Effects of family history and consanguinity in primary immunodeficiency diseases in children in Qatar

... Background: The high consanguinity in Middle East increases the risk of genetic diseases, in- cluding primary immunodeficiency diseases (PID). Objectives: This study was aimed at de- termining the ...

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An evaluation of the budget impact of a new 20% subcutaneous immunoglobulin (Ig20Gly) for the management of primary immunodeficiency diseases in Switzerland

An evaluation of the budget impact of a new 20% subcutaneous immunoglobulin (Ig20Gly) for the management of primary immunodeficiency diseases in Switzerland

... Introduction: While most individual primary immunodeficiency diseases (PID) are rare, the collective prevalence of PID results in a substantial economic and clinical burden. The aim of this study was to ...

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Subcutaneous immunoglobulin therapy: a new option for patients with primary immunodeficiency diseases

Subcutaneous immunoglobulin therapy: a new option for patients with primary immunodeficiency diseases

... Abstract: Since the 1950s, replacement of immunoglobulin G using human immunoglobulin has been the standard treatment for primary immunodeficiency diseases with defects in antibody production. These ...

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Immunologic responses to bacteriophage ϕX 174 in immunodeficiency diseases

Immunologic responses to bacteriophage ϕX 174 in immunodeficiency diseases

... immunodeficiency diseases. In eight cases of infantile X-linked agammaglobulinemia, there was prolonged circulation of phage and no detectable antibody response. The remaining 18 patients cleared phage ...

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ALLERGIC MANIFESTATIONS OF PRIMARY IMMUNODEFICIENCY DISEASES AND ITS TREATMENT APPROACHES

ALLERGIC MANIFESTATIONS OF PRIMARY IMMUNODEFICIENCY DISEASES AND ITS TREATMENT APPROACHES

... Selective IgA deficiency is the most common PID. The patients may be asymptomatic, have recurrent infections, or autoimmune diseases. Patients with selective IgA deficiency can also suffer from allergic disorders ...

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Primary immunodeficiency diseases in lung disease: warning signs, diagnosis and management

Primary immunodeficiency diseases in lung disease: warning signs, diagnosis and management

... New warning signs alerting to a suspicion of PID are being increasingly described, based on clinical presenta- tions - mainly infectious diseases - and, in some cases, family history. Fifteen years ago, the ...

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Purinogenic Immunodeficiency Diseases: DIFFERENTIAL EFFECTS OF DEOXYADENOSINE AND DEOXYGUANOSINE ON DNA SYNTHESIS IN HUMAN T LYMPHOBLASTS

Purinogenic Immunodeficiency Diseases: DIFFERENTIAL EFFECTS OF DEOXYADENOSINE AND DEOXYGUANOSINE ON DNA SYNTHESIS IN HUMAN T LYMPHOBLASTS

... Deoxyadenosine and deoxyguanosine are toxic to human lymphoid cells in culture and have been implicated in the pathogenesis of the immunodeficiency states associated with adenosine deaminase and purine nucleoside ...

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Human normal immunoglobulin in the treatment of primary immunodeficiency diseases

Human normal immunoglobulin in the treatment of primary immunodeficiency diseases

... Abstract: The primary antibody deficiency syndromes are a rare group of disorders that can present at any age, and for which delay in diagnosis remains common. Replacement therapy with immunoglobulin in primary antibody ...

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Clinical Features That Identify Children With Primary Immunodeficiency Diseases

Clinical Features That Identify Children With Primary Immunodeficiency Diseases

... The strongest identifiers of PID were a family history of immunodeficiency disease in addition to use of intravenous antibiotics for sepsis in children with neutrophil PID and failure to t[r] ...

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Antibody Dependent Cellular Cytotoxicity in Primary Immunodeficiency Diseases and with Normal Leukocyte Subpopulations: IMPORTANCE OF THE TYPE OF TARGET

Antibody Dependent Cellular Cytotoxicity in Primary Immunodeficiency Diseases and with Normal Leukocyte Subpopulations: IMPORTANCE OF THE TYPE OF TARGET

... To gain insight into a possible role for antibody-dependent cell-mediated cytotoxicity in vivo, we examined the ability of leukocytes from 28 patients with primary immunodeficiency and from 20 normal controls to ...

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Costs of Hospital Admission on Primary Immunodeficiency  Diseases

Costs of Hospital Admission on Primary Immunodeficiency Diseases

... for immunodeficiency located in this hospital is the documenting center of European society for Immunodeficiency and PID patients are diagnosed and treated in this center based on the updated standardized ...

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Serum IgD and IgE concentrations in immunodeficiency diseases

Serum IgD and IgE concentrations in immunodeficiency diseases

... well-defined immunodeficiency in an effort to find information possibly relevant to the roles of antibodies of these classes in host ...X-linked immunodeficiency with hyper-IgM and in those with ataxia ...

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Serum selenium and skin diseases among Nigerians with human immunodeficiency virus/acquired immune deficiency syndrome

Serum selenium and skin diseases among Nigerians with human immunodeficiency virus/acquired immune deficiency syndrome

... Results: The mean age of HIV subjects with and without skin disease were not significantly differ- ent: 32.72 ± 9.21 versus 35.86 ± 8.55 years, P = 0.077, respectively. The mean of serum selenium (0.51 ± 0.48 versus 0.81 ...

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Rising rates of injection drug use associated infective endocarditis in Virginia with missed opportunities for addiction treatment referral: a retrospective cohort study

Rising rates of injection drug use associated infective endocarditis in Virginia with missed opportunities for addiction treatment referral: a retrospective cohort study

... The UVA Clinical Data Repository was searched using International Classification of Diseases, Ninth Revision and Tenth Revision (ICD) diagnosis codes for acute and sub- acute IE (421, 421.1, 421.9, 424.9, 424.99, ...

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Human Immunodeficiency Virus Associated Chronic Lung Disease in Children and Adolescents in Zimbabwe: Chest Radiographic and High Resolution Computed Tomographic Findings

Human Immunodeficiency Virus Associated Chronic Lung Disease in Children and Adolescents in Zimbabwe: Chest Radiographic and High Resolution Computed Tomographic Findings

... <2 mm) is a common incidental pathological finding [26, 27]. The underlying mechanism is inflammation, which then causes partial or complete obliteration [28]. OB can occur as a sequel to diverse “insults,” including ...

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Genetic analysis of simian virus 40 from brains and kidneys of macaque monkeys.

Genetic analysis of simian virus 40 from brains and kidneys of macaque monkeys.

... Thus, SV40 appears to be an opportunistic pathogen in the setting of simian immunodeficiency virus-induced immunodeficiency, similarly to JC virus in human immunodeficiency virus-infecte[r] ...

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Cost effectiveness of community based HIV self testing in Blantyre, Malawi

Cost effectiveness of community based HIV self testing in Blantyre, Malawi

... Human Immunodeficiency Virus (HIV) Testing and Linkage Into HIV Care Trial data were used to derive probabilities for accessing each testing modality by sex and age ...

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Lentivirus-Specific Cytotoxic T-Lymphocyte Responses Are Rapidly Lost in Thymectomized Cats Infected with Feline Immunodeficiency Virus

Lentivirus-Specific Cytotoxic T-Lymphocyte Responses Are Rapidly Lost in Thymectomized Cats Infected with Feline Immunodeficiency Virus

... example, immunodeficiency-causing lentiviruses, such as human immunodeficiency virus type 1 (HIV-1), simian immunodeficiency virus, and feline immuno- deficiency virus (FIV), deplete CD4 ⫹ T ...

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“The others look at you as if you are a grave”: a qualitative study of subjective experiences of patients with epilepsy regarding their treatment and care in Cape Town, South Africa

“The others look at you as if you are a grave”: a qualitative study of subjective experiences of patients with epilepsy regarding their treatment and care in Cape Town, South Africa

... The study setting is one of the oldest urban townships in Cape Town which was developed as a result of the past laws of the oppressive colonial and apartheid rule. The predominant spoken language is isiXhosa – but there ...

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Cranial CT in Acquired Immunodeficiency Syndrome: Spectrum of Diseases and Optimal Contrast Enhancement Technique

Cranial CT in Acquired Immunodeficiency Syndrome: Spectrum of Diseases and Optimal Contrast Enhancement Technique

... TABLE 5: CT Scan Data and Clinical Outcomes in Acquired Immunodeficiency Syndrome Patients Treated for Toxoplasma Encephalitis and Having Follow-up CT Scans No.. and locations of lesions[r] ...

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