Immunosuppressive Agents
Emergence of sporadic non clustered cases of hospital associated listeriosis among immunocompromised adults in southern Taiwan from 1992 to 2013: effect of precipitating immunosuppressive agents
... L. monocytogenes is a common colonizer of the human gastrointestinal tract with the asymptomatic carrier rate in the general population reported to be 1–10% [3]. The occurrence of invasive listeriosis depends on the ...
8
Changing perspective on oncometabolites: from metabolic signature of cancer to tumorigenic and immunosuppressive agents
... Tumour microenvironment is a complex milieu, where some molecules are depleted while others abound. In vivo studies showed that extracellular ATP levels are higher at tumour sites, when compared to tumour- free tissues ...
15
Effects on muscle tissue remodeling and lipid metabolism in muscle tissue from adult patients with polymyositis or dermatomyositis treated with immunosuppressive agents
... the immunosuppressive and anti-inflammatory effects of GC are mediated through transrepression, downregu- lating the expression of pro-inflammatory cytokines such as IL-1, tumor necrosis factor (TNF) and IFNγ ...
13
Failure of remission induction by glucocorticoids alone or in combination with immunosuppressive agents in IgG4 related disease: a prospective study of 215 patients
... When the patients treated with GC monotherapy were grouped according to the number of risk factors at baseline, we identified a trend towards higher incidence of remission induction fail[r] ...
12
Behcet’s disease in budd-chiari syndrome
... Early diagnosis of BD is necessary in BCS patients to begin early and specific treatment for BD. Indeed in the present study and in the literature, pharmacological antic- oagulation and immunosuppression alone were ...
9
Budget impact analysis of conversion from cyclosporine to sirolimus as immunosuppressive medication in renal transplantation therapy
... Methods: An Excel-based model was developed to determine cost of RTT, comparing current CsA based therapy to an mTOR inhibitor-based therapy regimen. Total cost included both cost of immunosuppressive ...
9
Immunosuppressive drugs and fertility
... Sirolimus alters the functioning of the hypothalamic– pituitary–gonadal axis [36, 37]. As a result, men with kidney transplants who are treated with sirolimus have lower serum testosterone levels and higher plasma con- ...
15
Conventional immunosuppressive therapy in severe Behcet’s Uveitis: the switch rate to the biological agents
... insufficient to maintain the disease under control, defined as having a history of at least 1 relapse of the disease in a year before admission that needed an escalation of the dose of oral corticosteroid or other ...
7
Prevalence and risk factors for chronic co-infection in pulmonary Mycobacterium avium complex disease
... of immunosuppressive agents are known risk factors for infection in patients with bronchiectasis and cystic fi bro- sis, 18 21 22 the factors associated with microorganism co-infections in patients with ...
10
Advances in Research on Immunological Checkpoint Inhibitors in Immunotherapy of Liver Cancer
... with immunosuppressive agents such as PD-1, PDL-1 and CTLA-4 may be superior to traditional treatment, which requires a large number of clinical trials to further ...
8
Effects of Corticosteroids on Immunity in Man I DECREASED SERUM IgG CONCENTRATION CAUSED BY 3 OR 5 DAYS OF HIGH DOSES OF METHYLPREDNISOLONE
... other immunosuppressive agents or immunologically mediated diseases, we gave 17 normal adult male volunteers 96 mg of methylprednisolone daily for 3-5 days and compared results with 12 untreated controls ...
13
Legionella pneumonia cases over a five-year period: a descriptive, retrospective study of outcomes in a UK district hospital
... Those who died during admission were significantly older than those who survived to discharge 79 years 95% CI 70–88 vs 60 years 95% CI 55–66, p15 mg/day or other immunosuppressive agents[r] ...
8
Long-term outcome in dogs with chronic enteropathies: 203 cases
... Muenster and others 2006, Allenspach and others 2007). Furthermore, only a few studies to date have investigated more long-term outcome in the different treatment categories (Allenspach and others 2006, 2007). The goal ...
6
Immunosuppressive therapy in children with primary nephrotic syndrome: single center experience, Karachi, Pakistan
... All children with first episode were treated with OP at 60 mg/m 2 /day for 4–6 weeks followed by slow tapering over 3–6 months. Initial two relapses were treated like first episode. Further categorization was done ...
8
Nanomedicines in renal transplant rejection – focus on sirolimus
... of immunosuppressive therapy is to prevent and treat organ rejection as well as prolong graft and patient ...of immunosuppressive agents (Table 1), kidney transplantation has become one of the most ...
8
Original Article Development and characterization of pig xenograft model for human hepatocellular carcinoma
... In summary, we have developed a large-animal human liver tumor xenograft model in the pig. Orthotopic implantation of human hepatoma cells using immunosuppressive agents leads to engraftment of tumor cells ...
12
A Study of Epidemiology and Therapeutic Response of Patients with Immune Thrombocytopenic Purpura
... Henrik Frederiksen and Kai Schmidt searched 221 adult ITP patients. Considering sex, 139 were women (63%) and 82 men (37%), yielding a female to male (F/M) ratio of 1.7:1 The median age of the entire population was 56.4 ...
9
Individualized immunosuppression in transplant patients: potential role of pharmacogenetics
... of immunosuppressive agents combined with their nar- row therapeutic index renders them a difficult class of drug to ...appropriate immunosuppressive regimens based on predicted risk of rejection and ...
10
Treatment of immunoglobulin G4 related sialadenitis: outcomes of glucocorticoid therapy combined with steroid sparing agents
... steroid-sparing immunosuppressive agents in IgG4-RS is ...of immunosuppressive agents at the beginning, while other experts think it is acceptable in some patients ...steroid-sparing ...
10
Simultaneous detection of eight immunosuppressive chicken viruses using a GeXP analyser based multiplex PCR assay
... The advantages of the GeXP-multiplex PCR assay in- clude its specificity and its high-throughput ability to differentiate eight immunosuppressive viruses. These ad- vantages stem from the use of chimeric and ...
12