IMP metallo-β-lactamase
Detection of IMP Metallo β Lactamase in Carbapenem Nonsusceptible Enterobacteriaceae and Non Glucose Fermenting Gram Negative Rods by Immunochromatography Assay
... detecting IMP, especially in Enterobacteriaceae, mainly because of the low MIC of ...four IMP-1- and one IMP-11-producing ...of IMP-1 isolated from one Japanese strain. Poor inactivation of ...
7
Metallo β Lactamase Producing Pseudomonas spp in Korea: High Prevalence of Isolates with VIM 2 Type and Emergence of Isolates with IMP 1 Type
... that metallo-β-lactamases (MBLs)-producing-Pseudomonas ...14 IMP-1-like and 39 VIM-2-like MBLs, emergence of IMP-6 was detected for the first ...but IMP-6 emerged in ...
5
Detection of VIM-1, VIM-2 and IMP-1 metallo- β-lactamase genes in Klebsiella pneumoniae isolated from clinical samples in Sanandaj, Kurdistan, west of Iran
... of metallo-beta-lact- amases ...ed metallo-β-lactamase (VIM), New Delhi metal- lo-β-lactamase (NDM) and imipenemase ...and IMP-1 in Japan ...and IMP-type MBLs in ...
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Metallo β Lactamase Producing Gram Negative Bacilli: Laboratory Based Surveillance in Cooperation with 13 Clinical Laboratories in the Kinki Region of Japan
... Metallo-  -lactamases (MBLs) are enzymes belonging to Ambler’s class B that can hydrolyze a wide variety of  -lac- tams, including penicillins, cephems, and carbapenems (14, 30, 42). The acquisition by ...
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Paramagnetism & structural biology : biochemical & biophysical analysis of imp-1 metallo-beta-lactamase
... clinical β-lactam drugs. A) The penams consist of the β-lactam ring fused with a 5-membered thiazolidine ...the β-lactam. Benzylpenicillin (i) was the first β-lactam discovered but is poor at ...
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Prevalence of metallo β lactamase acquired genes among carbapenems susceptible and resistant Gram negative clinical isolates using multiplex PCR, Khartoum hospitals, Khartoum Sudan
... Verona integron Metallo beta-lactamase (VIM) was the most frequent genes 28(38.9%) out of 72 MBL detected genes, followed by imipenemase (IMP) was 19(26.4%), and consequently, New Delhi ...
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Systematic review of carbapenem-resistant Enterobacteriaceae causing neonatal sepsis in China
... spectrum β-lactamase; KPC: K. pneumoniae carbapenemase; MBLs: metallo- β-lactamases; NDM: New Delhi metallo-β-lactamase; VIM: verona integrin- encoded ...
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Dissemination of Pseudomonas aeruginosa producing blaIMP-1 and blaVIM-1 in Qazvin and Alborz educational hospitals, Iran
... of metallo-β-lactamase (MBL) among carbapenem non-susceptible isolates by combined disk (CD) method, and to detect the bla IMP , bla VIM , bla SIM , bla GIM , bla SPM and bla NDM-1 -MBL ...
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Metallo β Lactamase Detection: Comparative Evaluation of Double Disk Synergy versus Combined Disk Tests for IMP , GIM , SIM , SPM , or VIM Producing Isolates
... CD and DDST analyses also were stratified into seven groups according to pathogen species and MBL type produced, as follows: (i) general group, includ- ing all isolates tested; (ii) Acinetobacter spp. group; (iii) P. ...
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Emergence of New Delhi Metallo-β-Lactamase (NDM) Producing Multidrug-Resistant Escherichia Coli in Sudan
... a β-lactam that is highly potent against Gram- negative bacteria, has been recognized as a last resort for treating of infections caused by multidrug-resistant ...bla IMP ), and ...
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NDM 1 Metallo β Lactamase and ArmA 16S rRNA methylase producing Providencia rettgeri clinical isolates in Nepal
... harboring metallo- β -lactamase (MBL) encoding genes, including IMP-type MBL producers in Japan [3,4]; VIM-type MBL, PER-1 extended-spectrum β - lactamase (ESBL) and 16S rRNA ...
5
IMP-68, a Novel IMP-Type Metallo-β-Lactamase in Imipenem-Susceptible Klebsiella pneumoniae
... conclusion, IMP-68 should be noted as a novel carbapenemase that does not sufficiently confer resistance to imipenem on Enterobacteriaceae due to the Ser262Gly substitution from ...IMP-11. IMP-68 ...
5
Nosocomial Outbreak Caused by Multidrug Resistant Pseudomonas aeruginosa Producing IMP 13 Metallo β Lactamase
... Detection of  -lactamase activity. Phenotypic screening for MBL production was carried out by the Etest MBL assay (AB Biodisk, Solna, Sweden), under the conditions recommended by the test manufacturer, and by the ...
5
Evaluation of carbapenem resistance using phenotypic and genotypic techniques in Enterobacteriaceae isolates
... to IMP (imipenem), MEM (meropenem) and ERT (ertap- enem) were confirmed by the antimicrobial gradient test in collected ...MHT. Metallo- β -lactamase (MBL) production was evaluated using ...
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Effect of metallo β lactamase production and multidrug resistance on clinical outcomes in patients with Pseudomonas aeruginosabloodstream infection: a retrospective cohort study
... and IMP genes were sequenced using the primer pairs IMP-A–IMP-B or VIM2004A-VIM2004B in combination with the class 1 integron primer pair 5CS and 3CS or alternatively VIM-2SQR ...and IMP genes ...
9
Detection Rate of Metallo-β-Lactamase-Expressing Genes; blaVIM-1, blaVIM-2 and blaSPM-1 in Pseudomonas aeruginosa Isolates
... bial disks used (Mast Co, UK) are shown in Table 1. Pseu- domonas aeruginosa ATCC27853 was applied as a control strain for the susceptibility testing. DDST was applied for phenotypic examination of MBLs. Therefore, 0.5 M ...
5
Evaluation of effluxpumps gene expression in resistant Pseudomonas aeruginosa isolates in an Iranian referral hospital
... Antimicrobial susceptibility tests. Antimicrobial susceptibility tests were performed using disk diffu- sion and minimum inhibitory concentration (MIC) methods. Antibiotics used in this study were chosen randomly from ...
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Probing the interaction of Aspergillomarasmine A (AMA) with metallo-β-lactamases NDM-1, VIM-2, and IMP-7
... with IMP-7. Stripping the metal from IMP-7 with EDTA inactivates the enzyme and that activity cannot be restored by reintroducing ...to IMP-7, as IMP-1 was Co(II)- substituted using the direct ...
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Structural and biochemical characterization of Rm3, a subclass B3 Metallo β Lactamase identified from a functional metagenomic study
... Characterization of Rm3 Metallo-β-Lactamase active site, the Rm3 structure more closely resembles that of the mobile B3 enzymes AIM-1 and.. In contrast to these clear differences in over[r] ...
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<p>Characterization of the IncFII-IncFIB(pB171) Plasmid Carrying <em>bla</em><sub>NDM-5</sub> in <em>Escherichia coli</em> ST405 Clinical Isolate in Japan</p>
... KY1497 was resistant to fl uoroquinolones and all β -lactams, including broad-spectrum cephalosporins and carbapenems, whereas it remained susceptible to tigecycline. The antimi- crobial susceptibilities of ...
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