in silico approach
In silico approach to predict candidate R proteins and to define their domain architecture
... coiled-coil prediction analysis, allowed us to divid into two sub classes: NBS-LRR (45 proteins) and CNL (310 proteins). Using the same procedure, proteins containing only a NBS domain have been divided into CC-NBS (30 ...
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In-Silico Approach Towards Protein Targets Related to Diabets Mellitus-An Overview
... In silico approach would favour the scientists for the discovery of structurally favoured potential compounds for treating the chronic disorder, diabetes ...
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Elucidation and Validation of Metabolic Activation of Human Mammary Carcinogen Dibenzo[a,l] pyrene and its Metabolites Using In silico Approach
... In silico approach studying the metabolic activation of various carcinogens, xenobiotics and other drugs but also opens the gateway for the study of other similar ...
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Natural phytochemicals: Potential anti-HCV targets in silico approach
... The molecular docking is a computational tool which used to predict the binding affinity between ligands and target receptor proteins (Kumar and Doss, 2016). In the present study, druglikeness properties of all the ...
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IN-SILICO APPROACH FOR THE IDENTIFICATION OF NEW MOLECULES FOR ALZHEIMER’S DISEASE (AD)
... in- silico technique for identifying active compounds from the chemical databases ...screening approach has become a very popular and efficient method for in-silico drug discovery process ...
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IN SILICO APPROACH FOR THE ASSESSMENT OF ORAL CANCER PROPERTY ON LIMONIA ACIDISSIMA
... ABSTRACT: Cancer is the abandoned growth of cells that invade and cause damage to surrounding tissue. Oral cancer appears as a growth or uncomfortable in the mouth that does not go away. Oral cancer, which includes ...
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THROMBOLYTIC EFFECT OF SOME ANTIBIOTIC DRUGS: IN VITRO AND IN SILICO APPROACH
... 15. Mohammad Shah Hafez Kabir IBH, Md. Kamal Hossain, Ebrahim Khan Samrat, Mohammad Nazmul Hoque Jony, Sheikh Montasir Uddin, Meher Ahmed Chowdhury, Mohammed Sohel Chowdhury, Abul Hasanat, Md. Mominur Rahman: IN ...
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COMPETITIVE MEASURES OF SOME PHYTOCONSTITUENTS FOR THROMBOLYTIC EFFECT: AN IN SILICO APPROACH
... This study aims to predict whether Podocarpusflavone A (isolated from Podocarpus imbricatus), Podocarpusflavone B (isolated from Psilotum nudum), Robustaflavone (isolated from Selaginella sellowii), ...
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pVAC-Seq: A genome-guided in silico approach to identifying tumor neoantigens
... As described above, pVAC-Seq relies on input gener- ated from the analysis of massively parallel sequencing data that includes annotated non-synonymous somatic variants that have been ‘translated’ into mutant amino acid ...
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In silico approach for the discovery of new PPARγ modulators among plant-derived polyphenols
... in silico study aimed at finding new selective human PPARγ (hPPARγ) modulators that are able to improve glucose homeostasis with reduced side effects compared with ...
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An in silico approach to study the interaction of phycobilisomes and chlorophyll in Anabaena cylindrica PCC7122
... To understand the role of these pigments pigments homology modelling of phycocyanin and allophycocyanin with chlorophyll in Anabaena cylindrica PCC7122 was investigated in the present st[r] ...
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Metabolomic study and in silico approach of DLBS1442 as progesterone receptor agonist
... The virtual screening protocol for PR agonist has retrospectively been validated using PLANTS, PyPLIF, and DUD-E database. On the other hand, the metabolomics study of DLBS1442 also leads us to the specific compounds ...
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Evaluation of in silico approach for prediction of presence of opioid peptides in wheat
... The identified peptides were then assayed for opioid activity by cAMP assay for confirmation 103.. of their bioactivity.[r] ...
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EVALUATION OF MEDICAL BENEFITS OF COCCINIA INDICA THROUGH IN-SILICO APPROACH
... Through our current In-silico study we were able to predict the better binding affinity of Cocinia indica against orphan nuclear receptor. The ligands 2R,3S-9-[[1,3-DIHYDROXY-4-FLUORO- 3-BUTOXY]METHYL]GU, pterin-6 ...
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Carp proteins as a source of bioactive peptides – an in silico approach
... Potential bioactive peptides predicted to be re- leased per protein molecule, frequency and relative frequency of the release of fragments with ACEi and antioxidative activity after gastric, duode- nal, and ...
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Flavanones: Potential antidengue targets in silico approach
... Pinocembrin [12], pinostrobin and naringenin [9] are known to exhibit antidengue activity. All docked flavanones show comparable dock score with respect to pinocembrin, pinostrobin and naringenin. Figure 1 shows hydrogen ...
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Exploring anti malarial potential of FDA approved drugs: an in silico approach
... for nitrofural. Considering such a polypharmacologi- cal potential of nitrofural, further experimental investi- gations on this FDA-approved drug can reveal insights into its usefulness as an anti-malarial agent. Other ...
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In Silico Approach for Designing Potent Inhibitors against Tyrosinase
... (LGA) approach was selected as the search algorithm for the global optimum binding position search among the three different search algorithms offered by AutoDock ...
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INHIBITION OF MYCOBACTERIAL GLYCOSYLTRANSFERASES WITH PHYTOCOMPOUNDS AN IN SILICO APPROACH
... The rapid development of computational tools remarkably helps in narrowing the gap between in vitro and in silico methods. Applications of these tools vary from genome sequencing to drug discovery. New medicines ...
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INHIBITION OF ACETYLCHOLINESTERASE IN ALZHEIMER’S DISEASE AN IN SILICO APPROACH
... So far, only five drugs have been approved by US FDA that temporarily slow worsening of symptoms for about six to twelve months. The limited number of therapeutic options for AD drives the exploration of new drugs. ...
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