In Situ Gel
PREFORMED GEL VS IN SITU GEL: A REVIEW
... In situ gel is a gelatinous solution when interacting with the eye due to changes in the physical properties of chemistry by the eye so as to not cause problems like the previous ...Preformed gel ...
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FORMULATION AND EVALUATION OF FLURBIPROFEN OCULAR IN SITU GEL
... ABSTRACT: Conventional ophthalmic preparations exhibit poor bioavailability due to the rapid precorneal elimination of the drug, and the physiological constraints imposed by the protective mechanisms of the eye lead to ...
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“A Review on in situ Gel: A Novel Drug Delivery System” by Dibyalochan Mohanty, Dr.Vasudha Bakshi, Nandini Simharaju, M. Akiful Haque, Chinmaya Keshari Sahoo, India.
... In this system gel is formed due to pH changes. In this method pH sensitive polymers or pH responsive are used. In pH sensitive polymers includes pendant acidic or basic groups that may accept or release protons ...
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Contemporary Development in Floating Oral In-Situ Gel: A Review
... In situ gel forming systems have been broadly examined, for their capability of producing the sustained and controlled drug ...in situ gel by means of prevalent routes like oral, nasal, ...
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IN SITU GEL SUSTAINED NASAL DRUG DELIVERY
... In situ Gel: To check permeation of drug and capacity of permeation enhancer which was added in ...cell. Gel containing drug equivalent to 10 mg was placed in donor chamber, at predetermined time ...
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Ophthalmic pH Sensitive In-Situ Gel: A Review
... in situ overcomes the problems when drop instilled into the eye it undergoes sol-gel transition and transition form in ...in-situ gel system which includes thermally triggered system, pH ...
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In situ gel based on gellan gum as new carrier for nasal to brain delivery of venlafaxine hydrochloride: In vitro evaluation and in vivo study
... of gel [35]. Gel strength is an important factor which can prolong the post nasal ...in situ gel must have suitable gel strength so as to administer easily and can be retained at the ...
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Thermosensitive In situ Gel for Ocular Delivery of Lomefloxacin
... gelation temperature from 37.2-34.2 for formulation LF4-LF6 with 2% concentration and 39.3-37.6 for LF7- LF9 with 3% concentration. There was gradual decrease in the gelling temperature even though concentration of ...
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FORMULATION AND EVALUATION OF ZOLPIDEM NASAL IN SITU GEL
... in situ gel was prepared and ...temperature, Gel strength, Mucoadhesive strength, and invitro drug release ...and gel strength and invitro drug release ...in situ gel containing ...
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<p>Primary Studies on Construction and Evaluation of Ion-Sensitive in situ Gel Loaded with Paeonol-Solid Lipid Nanoparticles for Intranasal Drug Delivery</p>
... sensitive gel matrix with good nasal ...in situ gel, although it had high gelation responsiveness and gel strength, its surface was easy to form a hydration layer, which was easy to be cleaned ...
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Floating Oral In-Situ Gel: A Review
... the application of electromagnetic radiation used to form gel. Acrylate or similar polymerizable functional groups are typically used as the polymerizable groups on the individual monomers and macromers because ...
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FORMULATION AND OPTIMIZATION OF THERMOREVERSIBLE IN-SITU GEL OF VENLAFAXINE HCl
... thermoreversible gel, Poloxamer 407 18% was used a thermoreversible gel-forming polymer as it formed gel at nasal physiological ...of gel strength, viscosity, drug content, and diffusion ...
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Optimization and evaluation of a thermoresponsive ophthalmic in situ gel containing curcumin-loaded albumin nanoparticles
... which is an indicator of optimum formulations. The optimized formulation was a free-flowing liquid below 30.9°C that transformed into a semi-solid gel above 34.2°C after dilution with simulated tear fluid. Results ...
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FORMULATION DEVELOPMENT AND EVALUATION OF IN SITU GEL OF LEVOFLOXACIN AND DEXAMETHASONE
... completely. After 24h carbopol 934 and HPMC 15cps were added slowly along with other excipients with continuous stirring for 2-3 hours for proper mixing and avoiding slug formation. Buffering and osmolality agents were ...
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FORMULATION AND EVALUATION OF AN OPHTHALMIC IN SITU GEL OF GENTAMICIN SULPHATE
... hydro gel depends on its intrinsic properties and envisaged therapeutic ...in situ-forming polymeric systems used to achieve prolonged contact time of drugs with the cornea and increase their ...
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Biodegradable in situ Gel for Subcutaneous Administration of Simvastatin for Osteoporosis
... Hence, an attempt was made to prepare and characterize biodegradable in situ gel for subcutaneous administration of a simvastatin, which could be useful in the treatment of osteoporosis. CS (degree of ...
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A NOVEL OPHTHALMIC DRUG DELIVERY SYSTEM: IN SITU GEL
... in-situ gel systems has received considerable attention over the past few years and increasing number of in-situ gel forming systems have been investigated and in the tear film as soon as the ...
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IN SITU GEL FORMING INJECTABLE DRUG DELIVERY SYSTEM
... in situ gel forming drug delivery systems such as ease of administration and reduced frequency of administration, improved patient compliance and ...in situ gels include gellan gum, alginic acid, ...
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A New In Situ Gel Formulation of Itraconazole for Vaginal Administration
... in-situ gel with poloxamer and hydroxypropylmethylcellulose formulations of itraconazole were prepared for vaginal ...typical gel-type mechanical spectra (G′ > G″) after the determined frequency ...
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ORAL IN-SITU GEL: A REVIEW
... in-situ gel forming system provided a suitable way of providing the controlled delivery of drug within the stomach with enhanced gastric ...In-situ gel gives advantages such as ease of ...
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