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in vivo studies

In vitro and in vivo studies of a novel bacterial cellulose-based acellular bilayer nanocomposite scaffold for the repair of osteochondral defects

In vitro and in vivo studies of a novel bacterial cellulose-based acellular bilayer nanocomposite scaffold for the repair of osteochondral defects

... in vivo studies revealed that acellular BC-based bilayer scaffolds simultaneously accelerated the regeneration of articular cartilage and subchondral bone in a rat model of ...

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In Vitro and In Vivo Studies of a Rapid and Selective Breath Test for Tuberculosis Based upon Mycobacterial CO Dehydrogenase

In Vitro and In Vivo Studies of a Rapid and Selective Breath Test for Tuberculosis Based upon Mycobacterial CO Dehydrogenase

... vitro studies, the bio- logical replicates were of the same cultures but split into independent Exetainer tubes, with gases from each tube analyzed ...in vivo studies, the biological replicates were ...

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Nanostructured model implants for in vivo studies: influence of well-defined nanotopography on de novo bone formation on titanium implants

Nanostructured model implants for in vivo studies: influence of well-defined nanotopography on de novo bone formation on titanium implants

... Abstract: An implantable model system was developed to investigate the effects of nanoscale surface properties on the osseointegration of titanium implants in rat tibia. Topographical nanostructures with a well-defined ...

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Optimized dispersion of nanoparticles for biological in vitro and in vivo studies

Optimized dispersion of nanoparticles for biological in vitro and in vivo studies

... nanoparticles and to set up an optimized nanoparticle dispersion method for in vitro and in vivo studies. For this purpose, we prepared different nanoparticle dispersions, measured the size and zeta ...

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In Vitro and In Vivo Studies of Chemotherapeutic Doxorubicin Analogs

In Vitro and In Vivo Studies of Chemotherapeutic Doxorubicin Analogs

... Anthracyclines remain widely prescribed and successful anticancer agents, despite serious side effects. Doxorubicin (DOX) is the most prominent anthracycline used to treat many cancers, including hematologic ...

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Novel lecithin-integrated liquid crystalline nanogels for enhanced cutaneous targeting of terconazole: development, in vitro and in vivo studies

Novel lecithin-integrated liquid crystalline nanogels for enhanced cutaneous targeting of terconazole: development, in vitro and in vivo studies

... in vivo skin deposition, representing the amount of Tr retained in the skin (mean μ g ± SEM), as shown in Table 3 revealed that lecithin-based liquid crystalline organogel exhibited rapid penetration of Tr into ...

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Lipid nanoparticles for transdermal delivery of flurbiprofen: formulation, in vitro, ex vivo and in vivo studies

Lipid nanoparticles for transdermal delivery of flurbiprofen: formulation, in vitro, ex vivo and in vivo studies

... The aim of the study is to prepare aqueous dispersions of lipid nanoparticles – flurbiprofen solid lipid nanoparticles (FLUSLN) and flurbiprofen nanostructured lipid carriers (FLUNLC) by hot homogenization followed by ...

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In vitro and in vivo studies of surface-structured implants for bone formation

In vitro and in vivo studies of surface-structured implants for bone formation

... Implants with microporous surfaces have been used in the clinic in recent years. Acid etching and sandblasting techniques are two methods commonly used to fabricate micropores on titanium implant surfaces. Studies ...

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Devil Facial Tumour Disease: In vivo studies in mice

Devil Facial Tumour Disease: In vivo studies in mice

... In the previous chapter, immunocompetent BALB/c and C57/BL6 mice were shown to consistently reject DFTD cells (Table 3-2). This rejection was a specific immune response that produced anti-DFTD antibodies and cytokines ...

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In vitro and in vivo studies on gelatin-siloxane nanoparticles conjugated with SynB peptide to increase drug delivery to the brain

In vitro and in vivo studies on gelatin-siloxane nanoparticles conjugated with SynB peptide to increase drug delivery to the brain

... The aim of our study was to confirm whether SynB- PEG nanoparticles decorated with gelatin-siloxane (SynB- PEG-GS) could traverse the blood–brain barrier from the systemic circulation and increase the dose of drug ...

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In vivo Studies on Pharmacokinetics, Toxicity and Immunogenicity of Polyelectrolyte Nanocapsules Functionalized with Two Different Polymers: Poly-L-Glutamic Acid or PEG

<p>In vivo Studies on Pharmacokinetics, Toxicity and Immunogenicity of Polyelectrolyte Nanocapsules Functionalized with Two Different Polymers: Poly-L-Glutamic Acid or PEG</p>

... of studies that analyze the possible toxicity of biodegradable nanocarriers in ...in vivo toxicity was demonstrated for poly( έ -caprolactone) lipid-core nanocap- sules, nanoparticles made of biotransestri ...

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IN-VITRO AND IN VIVO STUDIES OF CETUXIMAB LOADED POLYMERIC NANOPARTICLES

IN-VITRO AND IN VIVO STUDIES OF CETUXIMAB LOADED POLYMERIC NANOPARTICLES

... Results of the in vivo biodistribution studies were statistically evaluated by Student’s t-test with P<0.05 as the minimal level of significance. Study was done in between free Cetuximab and Cetuximab ...

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In vitro and in vivo studies of bovine parvovirus proteins.

In vitro and in vivo studies of bovine parvovirus proteins.

... When the products of a single translation reaction were immunoprecipitated first with preimmune IgG and then with rabbit immune IgG, the virion proteins were detected in approximately th[r] ...

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TiO2 nanotube platforms for smart drug delivery: a review

TiO<sub>2</sub> nanotube platforms for smart drug delivery: a review

... of studies involving ex vivo and in vivo animal models have been performed to prove the excellent biocompatibility of the TNT ...tolerability studies carried out on animals to evaluate the ...

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Hypoxia-targeted 131 I therapy of hepatocellular cancer after systemic mesenchymal stem cell-mediated sodium iodide symporter gene delivery

Hypoxia-targeted 131 I therapy of hepatocellular cancer after systemic mesenchymal stem cell-mediated sodium iodide symporter gene delivery

... in vivo studies and to Alexandra Wechselberger (Medizinische Klinik und Poliklinik IV, LMU Munich, Munich, Germany) for her support with spheroid invasion ...imaging studies, Doris Mayr (Department ...

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INTRANASAL DRUG DELIVERY – NEW CONCEPT OF THERAPEUTIC IMPLICATIONS FOR EFFECTIVE TREATMENT OF CNS DISORDERS

INTRANASAL DRUG DELIVERY – NEW CONCEPT OF THERAPEUTIC IMPLICATIONS FOR EFFECTIVE TREATMENT OF CNS DISORDERS

... in vivo studies that higher concentration of hexarelin (a growth hormone releasing neuropeptide) was attained in the brain and cerebro spinal fluid when delivered through intranasal route when compared to ...

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The Influence of Morinda citrifolia (Noni) Fruit Juice on Collagen Deposition in the Skin: A Minireview

The Influence of Morinda citrifolia (Noni) Fruit Juice on Collagen Deposition in the Skin: A Minireview

... The results of clinical trials involving pediatric burn patients, cigarette smokers, and overweight adults, as well as the results of a cross-sectional popu- lation study, provide more insight into the potential effect ...

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DESIGN, CHARECTERIZATION AND IN-VITRO, IN-VIVO CORRELATION STUDIES FOR ELETRIPTAN LOADED TRANSDERMAL PATCHES

DESIGN, CHARECTERIZATION AND IN-VITRO, IN-VIVO CORRELATION STUDIES FOR ELETRIPTAN LOADED TRANSDERMAL PATCHES

... release studies: The in-vitro release profile data of Eletriptan were given in table No- ...in vivo studies in rabbits and the results obtained are shown in the table ...

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ORAL DELIVERY OF ROSUVASTATIN LIPID NANOCARRIERS: INVESTIGATION OF IN VITRO ANDIN VIVO PROFILE

ORAL DELIVERY OF ROSUVASTATIN LIPID NANOCARRIERS: INVESTIGATION OF IN VITRO ANDIN VIVO PROFILE

... Prescreening studies enabled in deciding the suitable process parameters, while factorial design facilitated in selection of lipid to surfactant ratio for developing optimized ROS lipid ...ex vivo and in ...

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Comparative Assessment of the Antibacterial Efficacy of Natural Products and Chlorhexidine Mouthwash against

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... Two studies established the effect of Triphala on Streptococcus mutans by comparing its antibacterial efficacy with chlorhexidine. In a study conducted by Srinagesh J et al., there was a significant reduction in ...

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