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in vivo toxicity

Size-dependent in vivo toxicity of PEG-coated gold nanoparticles

Size-dependent in vivo toxicity of PEG-coated gold nanoparticles

... A size-dependent in vivo toxicity study of PEG-coated gold nanoparticles in mice was carried out. In the study animals, survival, weight, hematology, biochemistry, and morphology were characterized 28 days ...

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Silica–gentamicin nanohybrids: combating antibiotic resistance, bacterial biofilms, and in vivo toxicity

Silica–gentamicin nanohybrids: combating antibiotic resistance, bacterial biofilms, and in vivo toxicity

... in vivo toxicity experi- ments under the supervision of ...in vivo toxicity experiments in Tsinghua ...in vivo toxicity results under the supervision of Prof ...

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Felodipine loaded PLGA nanoparticles: preparation, physicochemical characterization and in vivo toxicity study

Felodipine loaded PLGA nanoparticles: preparation, physicochemical characterization and in vivo toxicity study

... Poly (D, L-lactic-co-glycolic acid) or PLGA is one of the most popular biodegradable and non toxic polymers used for preparation of microparticles and nanoparticles [15,16]. PLGA is randomly hydrolyzed into their bio- ...

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In vitro characterization and in vivo toxicity, antioxidant and immunomodulatory effect of fermented foods; Xeniji™

In vitro characterization and in vivo toxicity, antioxidant and immunomodulatory effect of fermented foods; Xeniji™

... health supplement [6, 8]. Xeniji is one of the commercial available fermented food that commonly consumed in Japan and Malaysia. However, the nutritional value, in vivo toxicity and bioactivities of Xeniji ...

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In-Vivo Toxicity Assessment of Biologically Synthesized Iron Oxide Nanoparticles in Zebrafish (Danio Rerio)

In-Vivo Toxicity Assessment of Biologically Synthesized Iron Oxide Nanoparticles in Zebrafish (Danio Rerio)

... in vivo toxicity evaluations and its dose-dependent effects on embryonic development in ...no toxicity to zebrafish embryos or ...demonstrated toxicity, killing 100% of the zebrafish ...

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In vitro antiretroviral activity and in vivo toxicity of the potential topical microbicide copper phthalocyanine sulfate

In vitro antiretroviral activity and in vivo toxicity of the potential topical microbicide copper phthalocyanine sulfate

... gross toxicity was seen at any concentration in ...in vivo as no significant toxicity was seen in non- polarized cervical explants or at concentrations up to 100 mg/mL in the mouse ...

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In vivo toxicity and antitumor activity of essential oils extract from agarwood (Aquilaria crassna)

In vivo toxicity and antitumor activity of essential oils extract from agarwood (Aquilaria crassna)

... The in vivo anti-colon cancer effect of the EOs extract was investigated on the HCT 116 subcutaneous tumor model established in NCR nu/nu nude mice. The results are presented as average tumor size ± SD (n = 6). ...

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Effect of MWCNT size, carboxylation, and purification on in vitro and in vivo toxicity, inflammation and lung pathology

Effect of MWCNT size, carboxylation, and purification on in vitro and in vivo toxicity, inflammation and lung pathology

... in vivo studies focused on two time points, 24 hours and 7 ...ex vivo component of this study, using lavaged cells ob- tained at 24 hr post MWCNT delivery, subsequently cul- tured for 24 hr, was highly ...

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Evaluation of In Vivo Toxicity of Dichloromethane: Methanolic Leaf Extracts of Prosopis Juliflora in Rat Models

Evaluation of In Vivo Toxicity of Dichloromethane: Methanolic Leaf Extracts of Prosopis Juliflora in Rat Models

... A number of studies have been done on biochemical and toxicological effects of phytochemicals in animals and reported in several referenced journals. Some of the mostly reported adverse effects include reduced animal ...

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Health concerns of various nanoparticles: A review of their in vitro and in vivo toxicity

Health concerns of various nanoparticles: A review of their in vitro and in vivo toxicity

... This toxicity affects lung ...the toxicity of quantum NPs at the level of human lung adenocarcinoma cells and found that these NPs induce cytotoxicity in the form of apoptosis and necrosis ...

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Assessment of the In Vivo Toxicity of Gold Nanoparticles

Assessment of the In Vivo Toxicity of Gold Nanoparticles

... cellular toxicity in cultured ...the toxicity due to their nanometer dimensions must be a major ...this toxicity, our study also provides an important basis for studying the environmental ...

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Cytotoxicity, in Vivo Skin Irritation and Acute Systemic Toxicity of the Mesoporous Magnesium Carbonate Upsalite®

Cytotoxicity, in Vivo Skin Irritation and Acute Systemic Toxicity of the Mesoporous Magnesium Carbonate Upsalite®

... Mesoporous inorganic solids with narrow pore size distributions have been subjected to extensive research in recent years [1]. Biomedicine is an emerging application field for these materials, for which a large number of ...

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Fabrication of novel vesicles of triptolide for antirheumatoid activity with reduced toxicity in vitro and in vivo

Fabrication of novel vesicles of triptolide for antirheumatoid activity with reduced toxicity in vitro and in vivo

... C57/B6 mice were used to detect in vivo toxicity of PPT. The mice were divided into six groups randomly (n = 10) and were treated with 2 mg/kg TP, 1 mg/kg TP, 0.5 mg/kg TP, 0.5 mg/kg PPT, PP (PP ...

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Anthelmintic potential and in vivo acute toxicity study of Piptadenia gonoachanta leaf aqueous extract

Anthelmintic potential and in vivo acute toxicity study of Piptadenia gonoachanta leaf aqueous extract

... in vivo toxicity of the aqueous extract of ...In vivo toxicity was assessed by biochemical, hematological and histological evaluation of Balb/C mice treated orally with EAU (100, 200 and 400 ...

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Comparative lung toxicity of engineered nanomaterials utilizing in vitro, ex vivo and in vivo approaches

Comparative lung toxicity of engineered nanomaterials utilizing in vitro, ex vivo and in vivo approaches

... their toxicity is not fully understood ...acute toxicity tests in mice (in vivo), mouse lung tissue slices (ex vivo), and mouse alveolar macrophages (in vitro) to extrapolate, and compare the ...

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Recent Advancement in in-vivo and in-vitro Toxicity Studies for Ayurvedic Formulation

Recent Advancement in in-vivo and in-vitro Toxicity Studies for Ayurvedic Formulation

... the toxicity of Ayurvedic ...The toxicity of the substance can be observed by: a) in vivo (using the whole animal), b) in vitro (Testing on isolated cell or ...In vivo toxicity study ...

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Parallel comparative studies on toxicity of quantum dots synthesized and surface engineered with different methods in vitro and in vivo

Parallel comparative studies on toxicity of quantum dots synthesized and surface engineered with different methods in vitro and in vivo

... In this study, we conducted a parallel comparative study in vitro and in vivo on the toxicity of three representative QDs prepared by two different synthetic routes and with three different surface ligands. ...

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IN VITRO AND IN VIVO ANTI HEPATOTOXIC EVALUATION OF ALPINIA GALANGA ON D  GALACTOSAMINE INDUCED TOXICITY

IN VITRO AND IN VIVO ANTI HEPATOTOXIC EVALUATION OF ALPINIA GALANGA ON D GALACTOSAMINE INDUCED TOXICITY

... The liver is a vital organ present in vertebrates and some other animals, and is typically the largest visceral organ. The liver plays a major role in transforming and clearing chemicals and is susceptible to the ...

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Aceclofenac nanocrystals with enhanced in vitro, in vivo performance: formulation optimization, characterization, analgesic and acute toxicity studies

Aceclofenac nanocrystals with enhanced in vitro, in vivo performance: formulation optimization, characterization, analgesic and acute toxicity studies

... in vivo performance, compared to unprocessed AC and marketed AC formulation in comparatively low ...in vivo drug absorption and resulting in improved in vivo antinociceptive ...

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Effects of surface charges of gold nanoclusters  on long-term in vivo biodistribution, toxicity, and cancer radiation therapy

Effects of surface charges of gold nanoclusters on long-term in vivo biodistribution, toxicity, and cancer radiation therapy

... in vivo effects of the surface chemistry of Au NCs are important for the development of both nanobiological inter- faces and potential clinical contrast reagents, but these properties are yet to be fully ...in ...

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