INDAZOLE DERIVATIVES
Synthesis and molecular docking studies of new substituted indazole derivatives for anti breast cancer activity
... New substituted indazole derivatives were synthesized and studied their docking properties. Their computational docking analysis supported them as good therapeutic agents to the breast cancer aromatase ...
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Synthesis and biological activities of a novel series of indazole derivatives
... The newly synthesized indazole derivatives were evaluated for analgesic, anti-inflammatory and antipyretic activities. The synthesized compounds have been characterized on the basis of IR, NMR, mass and ...
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Synthesis and biological evaluation of some new Aryl acid N' (1Hindazole 3 carbonyl) hydrazide derivatives
... paradigm. Indazole derivatives are one of the privileged structural fragments in medicinal chemistry having broad spectrum of potent pharmacological activities including anti-inflammatory, anti-tumor, or ...
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STUDIES ON THE SYNTHESIS OF NOVEL INDAZOLES, PYRIMIDINE FUSED INDAZOLES, QUINOLINES AND OXAZINES OF BIOLOGICAL INTEREST AND DEVELOPMENT OF SYNTHETIC METHODOLOGIES
... conditions obtained pyrimido[1,2-b]indazole derivatives in single step. The role of substituents in 1,3-diketones and compounds 5a, 5b on formation of products 6 is studied in detail. In case of reaction of ...
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1 Allyl 6 nitro 1H indazole
... Indazole derivatives constitute an exciting heterocyclic family because of their important biological activities. Thus substituted indazoles are generally found to be of pharmaceutical interest in a variety ...
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2 Allyl 7 nitro 2H indazole
... The indazole subunit in organic molecules is an important structure in many drug substances with a wide range of pharmacological effects: ...the indazole derivatives published recently by our team ...
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1 (4 Methylphenylsulfonyl) 5,6 dinitro 1H indazole
... Indazole derivatives are a versatile class of compounds that have found use in biology, catalysis, and medicinal chemistry (Schmidt et ...sulfonamide derivatives published recently by our team ...
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Hydrogen bonded networks in 1H indazoles: the case of 7 methyl 1H indazole
... nine indazole derivatives in the CSD are distributed as follows: the parent compound (INDAZL), two compounds with substituent only at C3 (phenyl, two polymorphic forms UHENUQ/UHENUQ01, and methylcarboxy, ...
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Crystal structure of 2 [2 (2,5 dichlorobenzyloxy) 2 (furan 2 yl)ethyl] 2H indazole
... system, indazole, is an important structural unit of many biologically active ...Some indazole derivatives have been shown to exhibit antifungal (Lebouvier et ...some indazole ...
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2 [2 (2,6 Dichlorobenzyloxy) 2 phenylethyl] 2H indazole
... For clinical uses of azole antifungals possessing an imidazole ring such as micozanole and econazole, see: Godefroi et al. (1969). Some indazole derivatives have been known as anti- fungal also, see: ...
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Synthesis and biological evaluation of some new indazole-3-carboxamide derivatives
... the indazole ring system has been a long standing ...the indazole derivatives reported in the literature proceed from benzene precursors in which the pyrazole moiety was generated by ring closure ...
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1 Allyl 3 chloro 5 nitro 1H indazole
... Indazole derivatives are an important class of heterocyclic pharmaceuticals because of their significant and broad spectrum of biological properties, including antitumor, anti-HIV, antimicrobial, ...
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6,6′ Dinitro 1,1′ (ethane 1,2 diyl)di(1H indazole)
... Indazole moiety have been nucleus is a pharmaceutically important and emerging heterocycle with a broad spectrum of activities including anti-microbial1, anti-cancer, anti-inflammatory, anti- platelet, and ...
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“Effect of Indazole and its Derivative on Aspirin Induced Gastric Ulcers in Rats” by Chakrapani Cheekavolu, M Muniappan, N Jagan, K Vidyalakshmi, India.
... Non-steroidal anti-inflammatory drug (NSAID) like aspirin is used for the treatment of rheumatoid arthritis, many inflammatory and related diseases as well as the prevention of cardiovascular thrombotic diseases. Gastric ...
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Synthesis of substituted indazoles from N tosylhydrazones using ionic liquid
... Indazole derivatives are a versatile class of compounds that have found use in biology, catalysis, and medicinal ...properties.[6] Derivatives of indazoles exhibit a broad spectrum of bioactivities ...
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Crystal structure of 3 chloro 1 methyl 5 nitro 1H indazole
... Indazole derivatives are a versatile class of compounds that have found use in biology, catalysis, and medicinal chemistry. They exhibit a variety of biological activities such as anti-microbial, ...
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AN EXPLORATION OF SUNDRY NATURE OF BENZOTRIAZOLE DERIVATIVES: A REVIEW
... This work professes that benzotriazole moiety not only show sundry nature but also enjoy celebrity status among medicinal or pharmacological community. Now a day, many research groups are doing collaborative research to ...
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Increased blood pressure in rats after long term inhibition of the neuronal isoform of nitric oxide synthase
... Abbreviations used in this paper: eNOS, endothelial NOS; iNOS, inducible NOS; L-NAME, Nv-nitro-L-arginine methyl ester; MD, macula densa; 7-NI, 7-nitro indazole; nNOS, neuronal NOS; NO, [r] ...
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cis 3 Phenyl 3,3a,4,5 tetrahydrobenzo[g]indazole 2 carboxamide
... disclosed that nucleophilic attack of semicarbazide took place on the carbonyl C atom, with retention of the ole®nic double bond. The straightforward conversion of (I) to (II) was therefore envisaged, permitting its ...
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Isolation of flavonol rhamnosides from Pometia pinnata leaves and investigation of α-glucosidase inhibitory activity of flavonol derivatives
... kaempferol derivatives and quercetin derivatives for α-glucosidase inhibitory ...kaempferol derivatives and four quercetin derivatives were chosen, which include eight derivatives, ...
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