INDOLE DERIVATIVES
Weak interactions in the crystal structures of two indole derivatives
... A search of the Cambridge Structural Database (CSD; Groom et al., 2016) revealed 24 indole derivatives with an ester group at the 2-position of the ring system. In terms of halogen substitution, there were ...
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Corrosion Inhibition of Nickel in HCl Solution by Some Indole Derivatives
... Most organic inhibitors contain at least one polar group with an atom of nitrogen, sulfur or oxygen, each of them in principle representing an adsorption center. The inhibitive properties of such inhibitors depend on the ...
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Synthesis and antitumor properties of bis indole derivatives
... A series of bis-indole derivatives have been designed and synthesized as potential cytotoxic agents. The result indicated that four newly synthesized compounds exhibited good cytotoxic activities. ...
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SYNTHESIS, CHARACTERIZATION AND BIOLOGICAL EVALUATION OF NOVEL INDOLE DERIVATIVES
... novel Indole derivatives were synthesized in two-step facile procedure and four in ...the derivatives were characterized using spectral studies like FT-IR ...synthesized derivatives were ...
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Study of Mass Spectra of Some Indole Derivatives
... In the work, a study of mass fragmentation routes by the electron-impact mass spectrometry data has been examined for two open chain intermediates of indole derivatives and two pyrroloquino- lines. By the ...
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Synthesis, Characterization and Anti-Microbial Activity of Indole Derivatives
... its derivatives have occupied a unique place in the chemistry of nitrogen heterocyclic ...The indole derivatives were known for their dying ...of indole derivatives having the ...
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ANTIHELMINTHIC AND ANALGESIC ACTIVITY OF SOME NOVEL INDOLE DERIVATIVES
... In the present investigation, we have synthesized a novel series of (1, 3, 4) oxadiazino-[6, 5- b]indole derivatives(V). The synthesized compounds have been characterized by IR, 1 HNMR and their mass number ...
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Different N—H⋯π interactions in two indole derivatives
... N—H interactions are now a well-recognised type of ‘non- classical’ weak bond (Desiraju & Steiner, 1999). They are of special significance in biological systems (Burley & Petsko, 1986; Levitt & Perutz, 1998) ...
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2D QSAR Study of Indole Derivatives for Anti Microbial Study
... Firstly 20 indole deravatives were selected of wide diverse functional group substituents. Using the Chem Draw software all the structures were made, based on the structure physic-chemical properties were ...
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INDOLE DERIVATIVES AND THEIR BIOLOGICAL APPLICATIONSA REVIEW
... occurring products. There has been an increasing interest in the use of indole derivatives as bioactive molecules against microbes, cancer cells, and various kinds of disorder in the human body. This paper ...
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Role of Microwave Technology in Synthesis of Medicinally Potent Indole Derivatives
... (3′-indolyl)benzo[h]quinoline derivatives via one-pot multi component reactions of aldehydes, 3- cyanoacetyl indoles with 5-aminopyrazol or ...and indole derivatives using on both microwave ...
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INDOLE DERIVATIVES WITH ANTICONVULSANT ACTIVITY AGAINST TWO SEIZURE MODELS
... A series of indole derivatives (3-6 & 8a) were synthesized from 2-phenyl-1H-indole (1) with an aim to get promising anticonvulsant agents. The compounds were characterized on the basis of their ...
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QSAR study on Indole derivatives
... An indole is characterized as a benzene ring fused to a nitrogen-containing five-membered heterocylic ...an indole derivative. Several thousand indole derivatives appear annually in chemical ...
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ANTI INFLAMMATORY AND ANALGESIC ACTIVITY OF SOME NEW INDOLE DERIVATIVES
... that indole derivatives exhibit varied biological and pharmacological properties ...(1,3,4)oxadiazino-[5,6-b]- indole derivatives(V) has been carried ...
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Reactivity of 3 Cyanoacetylindole Derivatives: Synthesisof 3 Hydrazonopyrazolyl and 3 Thiadiazolyl Indole Derivatives
... sence of a signal for the methylene group and appearance of two deuterium oxide exchangeable protons at δ 6.40 ppm for amino group. it is believed that 4a-e has resulted from in stiu cyclization of the initially formed ...
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Synthesis, Characterization and Anthelmentic Activity of Indole Derivatives
... Indole is a planar molecule with a conjugated system of 10 electrons. It exists in resonance form with resonance energy of 47-49 K cal/mole. It is a very weak base with Pka value 3.63. In structure a, b, and d ...
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3 [2 (2,4 Dichlorophenyl)vinyl] 2 methyl 1 phenylsulfonyl 1H indole
... the indole moiety are comparable with those observed in related N-phenylsulfonyl indole derivatives (Sankaranarayanan et ...the indole moiety is due to the electron-withdrawing character of ...
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Hydrogen bonding in 1′ nitro 2′ phenyl 2′,3′,4′,5′,6′,7′ hexahydro 1H indole 3 spiro 3′ 1′H pyrrolizidin 2(3H) one: molecular chains built from alternating (18) and (8) rings
... of indole compounds has been extensively studied partly due to their use as pharmaceutical and industrial ...the indole derivatives are used as neuroprotectants (Stolc, ...of indole and ...
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ONE POT SYNTHESIS OF 2 (CYCLOHEXYLAMINO) 6,7 DIHYDRO 3 (2 HYDROXYPHENYL) 6,6 DIMETHYL 1H INDOL 4(5H) ONES AS POTENTIAL ANTICANCER AGENTS
... 1807 with aminoalkyl or aryl substituents at the 3-position are considered as venerable pharmacophores in drug discovery [8] and are found in several natural products [9] such as 5- HT1B/1D with receptor agonist ...
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XszenFHal, a novel tryptophan 5-halogenase from Xenorhabdus szentirmaii
... towards indole (16) and 3-substituted derivatives (4; 13-15) (Tables 1, ...simple indole derivatives is possible except in the case of tryptamine (4) (Somei et ...the indole moi- ety is ...
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