induced apoptosis
ZNF32 protects against oxidative stress-induced apoptosis by modulating C1QBP transcription
... of Sp1, leading to C1QBP downregulation, mitochondrial dysfunction and antioxidant system impairment and ultimately resulting in extreme ROS accumulation, p38 MAPK pathway activation, and cell death. As growing cancer ...
20
Mitochondrial Dysfunction in Lyssavirus-Induced Apoptosis
... Therefore, HeLa cells were cotransfected with various chi- meric forms of M fused to the C terminus of EGFP and the reporter plasmid DsRed2-Mito, coding for CcO7, which is used as a specific mitochondrial marker. Cells ...
11
-induced apoptosis in neonatal cardiomyocytes
... cardiomyocyte apoptosis is one of the major causes of cardiac dys- ...-induced apoptosis in neonatal mice cardiomyocytes in a time-dependent ...hypoxia-induced apoptosis in car- ...
6
Original Article p53 is essential for embelin-induced apoptosis in p53-wildtype prostate cancer cells
... embelin induced strong caspase 3 activation in LNCaP-siCon cells, while in LNCaP-sip53, such effects were significantly weakened at both drug concentrations tested (Figure ...embelin induced strong ...
10
Involvement of FAN in TNF induced apoptosis
... FAN and TNF-induced apoptosis. Both extracellular and intracellular regions of TNFRs contain essential motifs for transducing the activities of TNF. Of crucial importance is the cytoplasmic part that ...
10
-induced apoptosis in PC12 cells
... cell apoptosis. In the initiation and development of AD, apoptosis results in neuro- nal loss, aggravates the pathological changes of the nerve cells, and affects learning and memory ...neuronal ...
9
Original Article Shikonin protects chondrocytes from interleukin-1beta-induced apoptosis by regulating PI3K/Akt signaling pathway
... Chondrocyte apoptosis is mostly responsible for the development and progression of ...(IL-1β)- induced chondrocyte apoptosis and the potential molecular ...chondrocyte apoptosis was detected ...
11
<p>Salinomycin and Sulforaphane Exerted Synergistic Antiproliferative and Proapoptotic Effects on Colorectal Cancer Cells by Inhibiting the PI3K/Akt Signaling Pathway in vitro and in vivo</p>
... and induced apoptosis of CRC ...and apoptosis was measured by fluorescence-activated cell sorting (FACS) based on annexin V-fluorescein isothiocyanate (FITC) and propidium iodide (PI) double ...of ...
13
treatment or serum deprivation induces autophagy and apoptosis in naked mole-rat skin fibroblasts by inhibiting the PI3K/Akt signaling pathway
... levels. The Bax/Bcl-2 ratio increased after 12 h of exposure to LY294002 or CQ. These data show that inhibiting the Akt pathway promotes autophagy and apoptosis in NMR skin fibroblasts. Furthermore, LY294002 or CQ ...
12
Nonstructural Protein of Infectious Bursal Disease Virus Inhibits Apoptosis at the Early Stage of Virus Infection
... The third important characteristic, as presented in this study, is that IBDV-induced apoptosis occurs at a late stage during virus infection in CEF cells. An increase in viral protein ex- pression was ...
9
Original Article Hydrogen sulfide preconditioning protects against myocardial ischemia/reperfusion injury in rats through inhibition of endo/sarcoplasmic reticulum stress
... crucial role in the protective effects of H 2 S against myocardial I/R injury. H 2 S is increas- ingly being recognized as an important gaseous messenger in the cardiovascular and nervous systems. Evidence is ...
12
Inhibitive effects of 15-deoxy-Δ<sup>12,14</sup>-prostaglandin J<sub>2</sub> on hepatoma-cell proliferation through reactive oxygen species-mediated apoptosis
... 2 induced apoptosis in HCC cell ...the apoptosis assays (Figure ...demonstrated apoptosis-related protein expression, including cytochrome C, Bax, caspase 3, caspase 9, caspase 8, and PARP1, ...
9
Apoptosis induced by parasitic diseases
... and apoptosis after blood-brain barrier ...to apoptosis in cells of the cerebellum and brain-stem, as demon- strated by terminal deoxynucleotidyl transferase dUTP nick end labelling ...similar ...
9
Therapeutic potential of flavonoids in spinal cord injury
... ischemia/reperfusion-induced apoptosis via extracellular regulated protein kinases 1/2 (ERK1/2) and phosphatidylinositol 3 kinase/ protein kinase B (PI3K/Akt) signaling in vitro(Jeong et ...with ...
26
Anticancer phototherapy using activation of E combretastatins by two photon–induced isomerization
... Combretastatin induced apoptosis on CHO cell monolayers was determined using Annexin V AlexaFluor 488 conjugate (Invitrogen) as an indicator for the loss of phospholipid asymmetry in the plasma membrane of ...
19
A potential molecular model for studying apoptosis enhanced by the interaction of BCL-G with JAB1 in swine
... staurosporine-induced apoptosis that was significantly enhanced by interaction of pBCL-G with ...The apoptosis at least partially depended on the activated caspase-8, -9 and ...
13
FLIP: a targetable mediator of resistance to radiation in non-small cell lung cancer
... IR-induced apoptosis, but had no impact on IR-induced apoptosis induction in the 34Lu normal lung fibroblast cell line (Figure 4B); we have previously shown that SAHA only downregulates FLIP ...
26
<p>LAPTM4B knockdown increases the radiosensitivity of EGFR-overexpressing radioresistant nasopharyngeal cancer cells by inhibiting autophagy</p>
... autophagy induced by serum starvation by binding to nonactivated ...and apoptosis was increased after irradiation, suggesting that LAPTM4B may affect irradiation-induced apoptosis and promote ...
17
TGF-β1 reduces the oxidative stress-induced autophagy and apoptosis in rat annulus fibrosus cells through the ERK signaling pathway
... and induced apoptosis and autophagy in human osteosarcoma cells, but had a minimal impact on JNK and ERK-2 ...chlorpyrifos-induced apoptosis by increasing ROS and acti- vating JNK and p38 ...
13
Phosphatidylinositol 3-kinase inhibitor(LY294002) induces apoptosis of human nasopharyngeal carcinoma in vitro and in vivo
... of apoptosis [2]. Akt can suppress apoptosis by directly interacting with and phosphorylating these proapoptotic ...and induced apoptosis in vitro and in ...
7