Induced Hepatotoxicity
HEPATOPROTECTIVE ACTIVITY OF AQUEOUS EXTRACT OF CURCUMA LONGA IN ETHANOL INDUCED HEPATOTOXICITY IN ALBINO WISTAR RATS
... (Morikawa T et al., 2002), thioacetamide (Shapiro H et al., 2006), and ethanol (Rukkumani R et al., 2004). Curcumin exhibits multiple anti-carcinogenic effects (Leu TH et al., 2002). Curcuma longa or curcumin has also ...
8
Evaluation of Hepatoprotective Activity of Aqueous Extract of Azadirachta Indica (Neem) Leaves Against Paracetamol Induced Hepatotoxicity in Alb
... The highly significant (p <0.001) reduction in the levels of serum AST, ALT, and Bilirubin and significant increase in serum protein levels in rats treated with aqueous extract of Azadirachta indica leaves + ...
13
A Case of Supplement-Induced Hepatotoxicity
... A 45-year-old Caucasian male presented with a two-week history of jaundice and right-upper quadrant (RUQ) abdominal pain. Transaminases and biliary enzymes were markedly elevated with hyperferritinemia and mildly ...
6
An evaluation of the protective role of vitamin C in reactive oxygen species-induced hepatotoxicity due to hexavalent chromium in vitro and in vivo
... induce hepatotoxicity and natural and synthetic antioxidants have been shown to exert protective effects, the related molecular and cellu- lar mechanisms as well as the potential anti-hepatotoxic protective effect ...
12
EFFECT OF “KARPURAVALLI” ON ANTIBIOTIC INDUCED HEPATOTOXICITY
... Drug induced hepatotoxicity manifests in many ways, from asymptomatic elevation of liver enzymes to complete hepatic ...were induced with rifampicin and treated with aqueous extract of Coleus ...
8
Antioxidant and hepatoprotective activity of Flemingia tuberosa Dalzell in CCl4-induced hepatotoxicity in rats
... The extract was standardized using a validated HPTLC method for kaempferol content. The antioxidant activity of the ethanolic extract of aerial parts of F. tuberosa was assessed by 1,1-diphenyl-2-picrylhydrazyl method. ...
7
Evaluation of Hepatoprotective Activity of Aqueous Extract of Azadirachta Indica (Neem) Leaves Against Paracetamol Induced Hepatotoxicity in Albino Rats.
... paracetamol induced hepato-toxicity in albino ...woth hepatotoxicity induced by paracetamol (2g/kg, single ...injury induced by paracetamol in ...paracetamol induced ...
12
Hepatoprotective activity of Limnophila repens against paracetamol-induced hepatotoxicity in rats
... paracetamol-induced hepatotoxicity might be due to the presence of an active concentration of phytoconstituents that might restore the glutathione levels in hepatocytes, due to which the functional ...
7
Hepatoprotective activities of aqueous extract of oyster mushroom (Pleurotus ostreatus) against lead-induced hepatotoxicity in albino Wistar rats (Rattus norvegicus)
... lead-induced hepatotoxicity in Rattus norvegicus (albino Wistar ...(AST)]. Hepatotoxicity- induced rats (group 2(control II)) showed increased level of ALT and AST ...lead induced ...
5
Chemoprotective Effect of Anogeissus Latifolia Bark Extract on Paracetamol- Induced Hepatotoxicity.
... This study was undertaken to investigate the chemoprotective activity of ethanol extract of the bark of Anogeissus latifolia (ALE) against Paracetamol induced hepatotoxicity in rat model. The ethanol ...
25
CHEMOTHERAPY INDUCED HEPATOTOXICITY
... chemotherapy-induced hepatotoxicity are characteristic and do not have a specific clinical or histological signature that is distinct from other agents which cause ...
6
“In Vitro Hepatoprotective Activity of Barleria montana Nees Leaves against Anti-Tubercular Drugs induced Hepatotoxicity in BRL3A Cell Lines” by Jyothi Basini, Mohana Lakshmi Sabapathi, India.
... Drug induced liver injury is a major issue for the pharmaceutical companies for the failure of the drug to get approved or for withdrawal of already marketed ...drug induced hepatotoxicity causes ...
7
Protective effect of ethanol extract of Gymnosporia montana (Roth) Bemth. in paracetamol-induced hepatotoxicity in rats
... paracetamol-induced hepatotoxicity. Hepatotoxicity in Wistar rats was induced by a single intraperitoneal dose of 500 mg/kg of paracetamol and studied by comparing parameters such as serum ...
5
Hepatoprotective Activity of Siringipaerathi Chooranam on Ccl4 and Paracetamol Induced Hepatotoxicity and Anti - Oxidant Activity in In-Vivo and In-Vitro Models.
... Cichorium intybus is a popular Ayurvedic medicine for the treatment of liver diseases. It is commonly known as kasni and is part of polyherbal formulations used in the treatment of liver diseases. In mice, liver ...
192
Silymarin nanoparticle prevents paracetamol-induced hepatotoxicity
... Silibin effects a concentration-dependent transition of bilayers to micellar structure. Isolated membrane studies have provided ample evidence that Sm prevents membrane disruption with increasing concentration. Silibin ...
11
Protective effect of quercetin in the regression of ethanol-induced hepatotoxicity
... Alcohol induced significant lipid peroxidation (Table 3). Level of malondialdehyde was increased significantly in ethanol treated group. This was signiÞ cantly reduced by quercetin supplementation. Upon alcohol ...
6
Hepatoprotective activity of Maavilingapattai Chooranam on CCl4, Paracetamol and Ethanol Induced Hepatotoxicity in In-vivo models
... There is no single test, including liver biopsy that can be used to diagnose drug- related Hepatotoxicity. Other causes of liver injury must first be considered with the use of a combination of serologic tests, ...
218
Piroxicam- Induced Hepatotoxicity
... Non-steroidal anti-inflammatory drugs (NSAIDs) are consumed massively worldwide and, along with antimicrobial agents, are the most frequent causes of drug-induced liver injury. The pharmacology of NSADs is broad ...
6
Hepatoprotective Activity of Aeschynomene Aspera Linn
... The hepatoprotective activity of benzene and alcoholic extracts of root of Aeschynomene aspera was investigated in rats for carbon tetrachloride induced hepatotoxicity. LD50 values for both extracts ...
8
Hepatoprotective activity of Astercantha longifolia (Nees.) extract against anti-tuberculosis drugs induced hepatic damage in Sprague-Dawley rats
... Rats have been used successfully to investigate INH and RIF-induced hepatotoxicity models [32-37]. Therefore, we selected rats to study the hepatoto- xic effect of antituberculosis drugs and hepatopro- ...
7