Induced Inflammation
Histone deacetylase 2 (HDAC2) attenuates lipopolysaccharide (LPS)-induced inflammation by regulating PAI-1 expression
... have been studied because of their utility in the treat- ment of chronic inflammatory disorders [21]. Theophyl- line is a bronchodilator that acts as an HDAC agonist [22]. Low doses of theophylline have been used to re- ...
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Unexpected inflammation in the sympathetic ganglia in thromboangiitis obliterans: more likely sterile or infectious induced inflammation?
... On the other hand, TAO might be a type of neuro- genic inflammation. This hypothesis could explain the skip lesions and corkscrews in the arteriography of TAO patients. It could also explain the close relationship ...
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Inhibitory effect of calotropis gigantea extract on ovalbumin-induced airway inflammation and arachidonic acid induced inflammation in a murine model of asthma
... airway inflammation characteristically associated with the infiltration of macrophages, lymphocytes, mast cell, neutrophils and eosinophils into the bronchial lumen [4, ...
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Radiation-induced inflammation and autoimmune diseases
... exposure. Inflammation is a complicated process that appears as damage of the vasculature, migra- tion of leukocytes into the irradiated area and the release of various immune system mediators [51, ...causing ...
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Endotoxemia induced inflammation and the effect on the human brain
... acute systemic inflammatory response mediated by high levels of cytokines, resulting in oxidative stress [9,20,21] and increased levels of cortisol [22]. These effects are dose-dependent [23], and currently the ...
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Lipopolysaccharide induced inflammation in the perivascular space in lungs
... lung inflammation induced following intratracheal instillation of ...lung inflammation observed were similar to those reported in various other studies using intratracheal instil- lation of LPS ...
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An ex vivo RT-qPCR-based assay for human peripheral leukocyte responsiveness to glucocorticoids in surgically induced inflammation
... systemic inflammation used in the present ...GC- induced gene expression in the early phase of postoperative ...of inflammation, ie, surgery, might provide deeper ...
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Intrapulmonary administration of bone-marrow derived M1/M2 macrophages to enhance the resolution of LPS-induced lung inflammation: noninvasive monitoring using free-breathing MR and CT imaging protocols
... LPS-induced inflammation and assess the possibility of inflammation resolution after intrapulmonary administration of either M1 or M2 macrophages subpopulations, mice (n = 6 per group) were scanned ...
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The Analgesic, Anti-Inflammatory and Anti-Pyretic Activities of Tinospora cordifolia
... Carrageenan-induced inflammation is a significant test for assessing a substance’s an- ti-inflammatory activity by evaluating the degree to which it inhibits the inflammatory mediators of acute ...
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Effects of Histidine and Dexamethasone on the Local Inflammation Induced by Histamine in Rats
... Histamine- induced inflammation has been well established as a valid model to study paw oedema and neutrophil infiltration in paw tissue after inflammatory ...
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Original Article MDG-1 prevents high glucose-induced cytotoxicity and inflammation in rat brain microvessel endothelial cells
... Abstract: Hyperglycemia-triggered accelerated endothelial cell injury is a critical event in the process of brain-asso- ciated microvascular disease. Ophiopogon japonicus is a traditional Chinese medicine used to treat ...
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A murine model of inflammation-induced cerebral microbleeds
... ICAM-1, IgG, Iba1, and GFAP immunohistochemistry To determine the role of endothelial damage and neuroinflammation in LPS-induced CMH develop- ment, ICAM-1 (marker of endothelial cell activation), parenchymal IgG ...
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Sepsis-induced lung inflammation is modulated by insulin
... fibroproliferative phase of ALI has been regarded as a late event, there is some evidence that it can start at the early stages [5,6]. We noticed that both non-diabetic and dia- betic rats displayed similar basal levels ...
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HE3286, an oral synthetic steroid, treats lung inflammation in mice without immune suppression
... Dehydroepiandrosterone (DHEA) is an abundant adre- nal steroid and a precursor in the biosynthesis of andro- gens, estrogens and other anti-inflammatory immune regulating steroids [14,15]. From studies reporting aber- ...
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TSLP Regulates Intestinal Immunity and Inflammation
... Although IECs appear to be the main source of TSLP within the intestine, recent work has indicated that innate cells may also represent a source of TSLP. Studies have demonstrated that mast cells upregulate both TSLP ...
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Effect of Lycopene and Genistein on Hepatic Inflammation and Fibrosis in Thioacetamide Induced Liver Injury in Rats
... Oxidative stress and inflammation are two of the most critical factors implicated in TAA-induced liver injury. The Nrf2 protein is redox-sensitive transcription factor that plays a role in induction of ...
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Prostaglandin dependent modulation of dopaminergic neurotransmission elicits inflammation induced aversion in mice
... the noninflamed state. EP1Rs control impulsive behavior under stress (36), augment some effects of cocaine (23), and are protec- tive against the development of social avoidance in response to repeated social defeat ...
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Inhibition of Airway Contraction and Inflammation by Pomalidomide in a Male Wistar Rat Model of Ovalbumin-induced Asthma
... TNF-α is a pro-inflammatory cytokine and does as an activator and regulator of inflammatory cells. 11 And plays a key role in asthma severity. 8 Therefore, TNF-α inhibitors such as thalidomide reduced symptoms of asthma ...
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Allergen presensitization drives an eosinophil dependent arrest in lung specific helminth development
... (Figure 5B). HDM sensitization in WT mice decreased the num- ber of larvae in the lung tissue and BAL in comparison with HDM- unsensitized Ascaris-infected WT mice, as seen previously (Figure 1). Strikingly, allergic ...
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Anti-inflammatory effects of Radix Gentianae Macrophyllae (Qinjiao), Rhizoma Coptidis (Huanglian) and Citri Unshiu Pericarpium (Wenzhou migan) in animal models
... increase induced by acetic acid Vascular permeability increase induced by acetic acid in the male ICR mice was determined following a modified Whittle method ...
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