Induced Neurotoxicity
N(2) L Alanyl L Glutamine Dipeptide Preventing Oxaliplatin Induced Neurotoxicity in Colorectal Cancer Patients
... Oxaliplatin induced neurotoxicity may require chemotherapy dose reduction or ...oxaliplatin-induced neurotoxicity has varied from 12% - ...oxaliplatin-induced neurotoxicity, but ...
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NEUROPROTECTIVE AND ANTIOXIDANT ROLE OF PREGABALIN IN STREPTOZOTOCIN INDUCED NEUROTOXICITY
... amelioration of defensive antioxidant enzyme levels and reduced the lipid peroxidation in sciatic nerves of STZ induced diabetic rat model. It also prevented the abnormal structural changes of sciatic nerve in ...
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Studies into the mechanism of arsenic-induced neurotoxicity
... As-induced neurotoxicity, its mechanism of action on the molecular level is not ...As-induced neurotoxicity in animals in vivo and in cell cultures in ...
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Contrast-Induced Neurotoxicity following Cardiac Catheterization
... contrast-induced neurotoxicity that followed a technically challenging cardiac catheterization in a 69-year-old ...Contrast-induced neurotoxicity should be found in the differential diagnosis ...
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Impact of Physalis angulata on Methotrexate-Induced Neurotoxicity
... Oxidative stress contributes in the pathogenesis of methotrexate (MTX)-induced damage in the various organs. Many agents have been tested experimentally to reduce or inhibit the oxidative stress. However, the ...
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Ameliorating effects of aged garlic extracts against Aβ induced neurotoxicity and cognitive impairment
... Lipid peroxidation is increased in neurodegenerative diseases such as AD. Polyunsaturated fatty acid levels, especially arachidonic acid and docosahexaenoic acid, are high in neuronal cells of brain. They are more ...
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Metronidazole-induced neurotoxicity in 26 dogs
... MRI performed on the dog in case 2 revealed bilateral symmetrical hyperintensity on T2-weighted and FLAIR images within the dentate nuclei. The dentate (or lateral) nucleus is a cluster of neurons located within the deep ...
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Protective Effects of Tetramethylpyrazine on Glutamate Induced Neurotoxicity in Mice
... glutamate-induced neurotoxicity, and the neuroprotection effect may result from its inhibiting expression of NMDARs, consequently blocking-up Ca 2+ influx through the receptor’s ...
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NEUROPROTECTIVE EVALUATION OF ETHANOLIC LEAF EXTRACT OF DALBERGIA SISSOO IN MONOSODIUM GLUTAMATE INDUCED NEUROTOXICITY IN RATS
... ABSTRACT: Neurodegenerative disorders are heterogeneous group of diseases of the nervous system, including the brain, spinal cord and peripheral nerves that have many different etiologies. Due to the prevalence, ...
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ATTENUATION OF MONOSODIUM GLUTAMATE INDUCED NEUROTOXICITY BY HYDROALCOHOLIC EXTRACT OF GLYCYRRHIZA GLABRA ROOTS IN ALBINO RATS
... The flavor enhancer monosodium glutamate (MSG) is a sodium salt of non-essential aminoacid glutamic acid. Because of flavor enhancing properties glutamate is deliberately added in food as purified monosodium salt. Many ...
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Ameliorative Potential Of Certain Antioxidants On Enodsulfan Induced Neurotoxicity On Cholinesterases In The Olfactory Lobe Of Mice
... toxicities induced by ...endosulfan induced neurotoxicity in olfactory lobe of the brain of Swiss albino mice on the basis of altered histochemical localization of acetylcholinesterase (AChE), ...
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A Role for Cell Cycle Protein E2F1 in HIV-Induced Neurotoxicity
... HIVMDM-induced neurotoxicity promotes neuronal damage in a NR2B receptor-dependent and calpain-dependent manner, the same manner in which E2F1 is cleaved (O'Donnell et ...
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<p>Monosialoganglioside protects against bupivacaine-induced neurotoxicity caused by endoplasmic reticulum stress in rats</p>
... showed localization of GRP78 protein in the cytoplasm of spinal dorsal horn neurons, which was significantly increased upon bupivacaine exposure (Figure 5A). Pretreatment with GM1 inhibited GRP78 expression on days 7 and ...
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Cefepime induced neurotoxicity: a systematic review
... cefepime- induced neurotoxicity, but 11 patients included in our review had preexisting CNS diseases and 2 patients had pre- existing seizure disorders [16, 20, 21, ...
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Neuroprotective activity of pongamia pinnata in monosodium glutamate-induced neurotoxicity in rats
... It is a well-known fact that the reactive oxygen species are involved in the pathogenesis of MSG- induced neurotoxicity. In the present study, increase in brain tissue MDA level along with decrease in ...
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OATP1B2 deficiency protects against paclitaxel induced neurotoxicity
... (23), we performed a screen with FDA-approved TKIs and con- firmed that several of these agents inhibited OATP1B1 function by at least 75% using 8-(2-[fluoresceinyl]-aminoethylthio)- adenosine-3′,5′-cyclic monophosphate ...
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GLP-1 Analogue Liraglutide Attenuates Mutant Huntingtin-Induced Neurotoxicity by Restoration of Neuronal Insulin Signaling
... induced oxidative stress is related to impaired neuronal insulin signaling and is a deleterious factor 178. that increases neurotoxicity[r] ...
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A Nucleotide based Drug Protects Against Glutamate and MPP+ Induced Neurotoxicity
... death induced by glutamate is mediated by activation of the N-methyl-D-aspartate (NMDA)-subtype receptor of Glu and involves an in- crease in intracellular calcium concentrations that leads to an intracellular ...
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Original Article Dexmedetomidine alleviated isoflurane-induced neurotoxicity in aged rats
... ly been reported that ISO caused decomposi- tion of APP and accelerated the process of senile dementia-related neurodegenerative di- seases [3]. In this study, we demonstrate that mRNA expression of APP in rats that ...
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MR imaging of reversible cyclosporin A induced neurotoxicity
... On postoperative day 23 16 days after the seizures, T2-weighted MR examination revealed complete resolution of the white matter lesions Fig.. Case 2 A 36-year-old man underwent cardiac t[r] ...
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