induced pluripotent stem cells (iPS)
Role of tumor suppressor genes in the cancer-associated reprogramming of human induced pluripotent stem cells
... their pluripotent characteristics, human induced pluripotent stem cells (iPSCs) possess great potential for therapeutic application and for the study of degenerative ...These ...
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Induced Pluripotent Stem Cells: History, Properties and Potential Applications
... of induced pluripotent stem cells (iPSCs) has been met with much enthusiasm and hailed as a breakthrough discovery by the scientific and research communities amidst the divisive and ongoing ...
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Generation of induced pluripotent stem cells from large domestic animals
... iPSCs: Induced pluripotent stem cells; OSKM: Oct4, Sox2, KFL4, and c-Myc; biPSCs: Bovine induced pluripotent stem cells; miPSCs: Mouse induced ...
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Induced pluripotent stem cells in infections
... state. stem cells which have the potential to differentiate into specific types of cells, offers a new concept of regenerative medicine to treat spectrum of diseases including ...states. ...
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Mouse induced pluripotent stem cells
... reprogrammed cells (Brambrink et ...identify cells at specific intermediate stages in the reprogram- ming process (by their specific gene marker expression) should prove useful in further deciphering the ...
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Induced pluripotent stem cells: advances to applications
... Abstract: Induced pluripotent stem cell (iPS) technology has enriched the armamentarium of regenerative medicine by introducing autologous pluripotent progenitor pools bioengineered from ...
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Biomedical Applications of Induced Pluripotent Stem Cells
... derived cells are utilized as testing systems but are restricted by their failure to imitate the “accurate” human physiological conditions and connected phenotypic ...iPS cells technology can offer a novel ...
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Pluripotency of induced pluripotent stem cells
... iPS cells and rescues the ability of iPS cells to support full-term development of iPS cell-derived mice ...iPS cells may not be determined by only one gene clus- ter, and that further comprehensive ...
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Induced pluripotent stem cells: An update
... The efficiency of induction is increased by many additional genes which have been identified as members of the Klf family such as Klf1, Klf2, Klf4, and Klf5; the Myc family such as c-myc, L-myc, and N-myc; Nanog, and ...
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Induced pluripotent stem cells in medicine and biology
... Human pluripotent stem cells generally show clonal variations in lineage bias, which allows for cells to be chosen that best suit the purposes of each application (Osafune et ...
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Modeling of Sic Power Semiconductor Devices For Switching Converter Applications
... human induced pluripotent stem cells were differentiated into endothelial cells and then injected into immunodeficient mice with ischemic ...positive cells and transplanted them ...
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Therapeutic use of stem cells for cardiovascular disease
... Induced pluripotent stem cells are attractive because of their ability to differentiate into large numbers of cardio- ...heart cells in comparison to adult cells, specifically in ...
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Disruption of histamine/H1R signaling pathway represses cardiac differentiation and maturation of human induced pluripotent stem cells
... beating cells in- creased in a histamine dose-dependent manner and reached a peak at the concentration of 10 μM ...differentiation induced by histamine was further confirmed by immunofluor- escence ...
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A SY Stematic approach towards understanding stem cell biology
... various stem cell research ...how stem cells make ‘ decisions ’ during early development and how stem cells function in the ...embryonic stem cells (ESCs), induced ...
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Mesenchymal stem cell-based cell-free strategies: safe and effective treatments for liver injury
... multipotent cells that are able to proliferate, self- renew, and differentiate into various somatic cells in vitro, and they have attracted much attention for re- storing tissue function in vivo with little ...
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Advances in Regenerative Medicine: From Stem Cells to Organoids
... used stem cells to develop substitute tissue/organs “ex vivo” with various degree of success, which the ultimate goal is to be trans- planted to replace a damaged organ ...various stem cells, ...
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Stem Cell Sources for Regenerative Medicine and Cartilage Tissue Engineering.
... Stem cells have been studied widely as a potential resource for regenerative medicine as they can proliferate for long-term while maintaining differentiation ...of cells and tissues within body. ...
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Stem cells: a model for screening, discovery and development of drugs
... conclusion, stem cells (both normal and cancerous) are a valuable tool in the drug discovery ...tumorigenic stem cell behavior (Figure ...embryonic stem cells are limited due to ethical ...
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Directly induced human Schwann cell precursors as a valuable source of Schwann cells
... iSCPs: Induced-Schwann cell precursors; iSCs: iSCP-derived Schwann cells; iPSC: Induced pluripotent stem cells; hESCs: Human embryonic stem cells; NCSCs: Neural ...
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Transplantation of induced pluripotent stem cell-derived mesenchymal stem cells improved erectile dysfunction induced by cavernous nerve injury
... Induced pluripotent stem cells (iPSC) are pluripotent stem cells generated by reprogramming somatic cells ...(induced pluripotent stem ...
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