Induced regulatory T cells
Induced regulatory T cells in allograft tolerance via transient mixed chimerism
... donor-reactive T cell clones in the tolerant recipients (19), substantial numbers of donor-reactive clones were still ...of regulatory mechanisms of tolerance was also supported by our recent studies ...
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Transforming growth factor β induced regulatory T cells referee inflammatory and autoimmune diseases
... of T cell growth and activation, with resultant overexuberant inflammation and tissue ...Although T cell responses to foreign antigens are essential to our protection from a plethora of potentially ...
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Regulatory T cells induced by B cells: a novel subpopulation of regulatory T cells
... of-B cells shared several characteristics with oral antigen administration activated CD4 + CD25 + T cells, including ele- vated expression levels of ICOS, PD1, and CTLA4 and en- hanced ...
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Pathogen specific T Regulatory 1 Cells Induced in the Respiratory Tract by a Bacterial Molecule that Stimulates Interleukin 10 Production by Dendritic Cells: A Novel Strategy for Evasion of Protective T Helper Type 1 Responses by Bordetella pertussis
... 34) cells, respectively, suggesting that they represent a phenotypically, as well as functionally, distinct subtype of CD4 T ...Th1, cells (27, ...Th2 cells, it is tempting to suggest that ...
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Impact of IL-27 on regulatory T cell responses
... While regulatory T (Treg) cells are critical to limit inflammation, their role during toxoplasmosis is controversial because this infection results in a dramatic decrease in the total numbers of ...
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Review Article Advances in distinguishing natural from induced Foxp3 regulatory T cells
... positive cells as suppressive T cells [1], regulatory T cells (Tregs) have been considered as a promising immunotherapy for clinical diseases, but there have been many dif- ...
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Influence of Dietary Components on Regulatory T Cells
... ment induced FoxP3 + Tregs in germ-free mice, indicating that even without preex- istence of bacterial flora, CpG-ODN in- duces tolerance, which suggests that CpG-ODN–induced Tregs are not bacter- ial ...
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CD4+ T Cells Develop Antiretroviral Cytotoxic Activity in the Absence of Regulatory T Cells and CD8+ T Cells
... ⴙ T cells play an important role in viral ...and T cell ...of regulatory T cells (Tregs) has been demonstrated, which can suppress virus-specific CD4 ⴙ T cell responses in ...
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Is there a feudal hierarchy amongst regulatory immune cells? More than just Tregs
... DCs are mainly regarded as specialized professional antigen presenting cells. In a resting environment, in the absence of any inflammation or pathogenic elements, most DCs are at an immature stage of development, ...
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Role of dendritic cells in the induction of regulatory T cells
... memory T cells, which secrete IL-4, IL-21 and IFN-g, and suppress TGF-b mediated iTreg differentia- tion ...suppress T cell mediated colitis upon transfer of Tregs, pointing towards a role of CD103 + ...
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The role of regulatory T cells in antigen induced arthritis: aggravation of arthritis after depletion and amelioration after transfer of CD4+CD25+T cells
... is induced by intra-articular injection of antigen (meth- ylated bovine serum albumin [mBSA]) into knee joints of preimmunized mice ...clear cells, and cartilage and bone destruction – his- topathological ...
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Subsets of regulatory T cells and their roles in allergy
... complicated T cell ...these cells are generated without looking into the intracellular signaling pathways of these cells, and their migration ...involving T-bet ...Th cells [23]. ...
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mTOR inhibitors effects on regulatory T cells and on dendritic cells
... CCR7 on human and mouse derived DCs and conse- quently promotes DCs migration into lymphoid tissue [62]. In contrast, the authors did not find significant bio- logical effects of CNIs cyclosporine and FK506 on DCs ...
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Original Article Combination of CD4 CD25 CD127 regulatory T cells with MLC-BE and BE-Ab2: an efficient evaluation of the therapy of paternal lymphocyte induced immunization in unexplained recurrent spontaneous abortion patients
... immuno-regulatory cells are thought to play a critical role in the control of T-cell mediated autoimmunity by suppressing the proliferation and cytokine production of other T ...
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BANK1 alters B cell responses and influences the interactions between B cells and induced T regulatory cells in mice with collagen induced arthritis
... B cells from the spleen and lymph nodes in mice with established arthritis on the 35th day after immunization ...B cells, which secrete antibodies in the humoral immune system and present antigens as ...
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Hypoxia-induced CCL28 promotes recruitment of regulatory T cells and tumor growth in liver cancer
... Tumor cells craft microenvironment to overcome growth disadvantages and adjust to escape the immunosurveillance during tumorigenesis and ...(HCC) cells recruited Regulatory T cells ...
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Diet-induced dyslipidemia induces metabolic and migratory adaptations in regulatory T cells
... Tconv cells, suggesting that the migratory and metabolic adaptations we observed can be Treg ...Treg cells might explain why the latter are more sensitive to perturbations in environmental lipid ...Tconv ...
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Nox2 in regulatory T cells promotes angiotensin II–induced cardiovascular remodeling
... dendritic cells may contribute to the formation of these oxidation products, and it was previously shown that dendritic cell Nox2 is involved in antigen presentation via MHC class II as a consequence of regulating ...
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Regulatory T cells in induced sputum of asthmatic children: association with inflammatory cytokines
... dendritic cells, monocytes/macrophages and lymphocytes induce, amplify or modulate the ongoing inflammation ...investigated regulatory T (Treg) cells in asthma [4,5], and it is possible that ...
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Nox2 in regulatory T cells promotes angiotensin II–induced cardiovascular remodeling
... Nox2-competent T cells ...by T cells was inhibited by scavenging ROS ...Nox2-containing T cell subsets remains ...Nox2-expressing cells are implicated in angiotensin ...
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