inducible nitric oxide synthase 2
Pulsed low frequency magnetic field on obese subjects
... of inducible nitric oxide synthase, endothelial nitric oxide synthase and cyclooxygenase-2 in the human nocyte cell line HaCat: potential therapeutic effects in ...
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Modulation of inducible nitric oxide synthase expression by sumoylation
... by 2 min at ...figure 2, changes in mRNA levels were estimated by quantitative PCR (QPCR) in the presence of SYBR Green (1:10,000 dilution of stock solution; Molecu- lar Probes, Invitrogen) carried out in a ...
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Anti-inflammatory property of Parkia speciosa empty pod extract in human umbilical vein endothelial cells
... 2017), inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) expression as well as proinflammatory cytokines, like tumor necrosis factor-α (TNF-α) (Hsu et ...
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Anti-inflammatory effect of ozonated krill (Euphausia superba) oil in lipopolysaccharide-stimulated RAW 264.7 macrophages
... -3′; inducible nitric oxide synthase (iNOS) forward and reverse primers: 5′- CAC CTT GGA GTT CAC CCA GT -3′ and 5′- ACC ACT CGT ACT TGG GAT GC -3′; interleukin-1 β (IL-1 β ) forward and ...
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Inducible Nitric Oxide Synthase and Inflammatory Diseases
... The demonstration of the involvement of NO in a number of autoimmune and inflamma- tory diseases does not necessarily imply that NO itself is the effector molecule. Whether these pathologies are directly mediated by NO ...
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EXPRESSION OF INDUCIBLE NITRIC OXIDE SYNTHASE IN CARDIOVASCULAR DISEASE
... Inflammatory cytokines associated with atherosclerosis may be capable of stimulating the synthesis and activity of inducible nitric oxide synthase (iNOS), which could further influence the ...
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Hypergravity upregulates renal inducible nitric oxide synthase expression and nitric oxide production
... Immunohistochemical staining for iNOS was performed using the Bond Polymer Intense Detection System (Vision Biosystems, Mount Waverley, Victoria, Australia). In brief, 4-μm thick sections of formalin-fixed, ...
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A new co-ultramicronized composite including palmitoylethanolamide and luteolin to prevent neuroinflammation in spinal cord injury
... In this study, using an ex vivo model of spinal cord organotypic cultures and an in vivo compression model of SCI in mice, we analyzed the neuroprotective properties of a co-ultramicronized combination product based on ...
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Inducible nitric oxide synthase links NF-κB to PGE2 in polyunsaturated fatty acid altered fibroblast in-vitro wound healing
... wounds after 5 days than dogs fed a diet enriched in n-6 fatty acids. However, the n-3 diet did not appear to have a negative effect on wound healing [20]. A more recent study found that topical application of oleic acid ...
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Activation of macrophage nuclear factor-κB and induction of inducible nitric oxide synthase by LPS
... clear extracts were prepared as described [19] and nuclear protein concentrations determined using the BCA (bicin- choninic acid) method (Pierce, Rockford, IL). The nuclear extract (3 µ g of protein) was preincubated for ...
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Effects of chitosan on nitric oxide production and inducible nitric oxide synthase activity and mRNA expression in weaned piglets
... sion in small intestine of piglets were improved in a dose-dependent manner with increasing chitosan supplementation. Shi (2004) showed that dietary supplementation with chitosan enhanced NO con- tent and iNOS activity ...
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Salidroside Regulates Inflammatory Response in Raw 264.7 Macrophages via TLR4/TAK1 and Ameliorates Inflammation in Alcohol Binge Drinking Induced Liver Injury
... mediated inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) protein levels, as well as their downstream products, ...
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TLR2 signal influences the iNOS/NO responses and worm development in C57BL/6J mice infected with Clonorchis sinensis
... 5]. Nitric oxide (NO) formation and nitrosation may contribute to the development of liver fluke-associated carcinogenesis ...by nitric oxide synthase ...NOS, inducible NOS ...
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AICAR Attenuates Organ Injury and Inflammatory Response after Intestinal Ischemia and Reperfusion
... lung-inducible nitric oxide synthase (iNOS) and cyclooxyge- nase-2 (COX-2) proteins, were decreased in the lungs and lung apoptosis was significantly reduced after AICAR ...
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Crude extract of hydatid laminated layer from Echinococcus granulosus cyst attenuates mucosal intestinal damage and inflammatory responses in Dextran Sulfate Sodium induced colitis in mice
... and nitric oxide (NO) ...of inducible nitric oxide synthase (iNOS) expression in macrophages, intestinal epithelial cells and other cells ...
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IRG1 and Inducible Nitric Oxide Synthase Act Redundantly with Other Interferon Gamma Induced Factors To Restrict Intracellular Replication of Legionella pneumophila
... ABSTRACT Interferon gamma (IFN- ␥ ) restricts the intracellular replication of many pathogens, but the mechanism by which IFN- ␥ confers cell-intrinsic pathogen resis- tance remains unclear. For example, intracellular ...
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Inducible nitric oxide synthase in rat hepatic lipocytes and the effect of nitric oxide on lipocyte contractility
... Transforming growth factor-beta 1 decreased IFN-gamma/TNF-alpha--stimulated iNOS mRNA and nitrite. Finally, the effect of NO on lipocyte contractility was examined. In cells incubated with IFN-gamma and TNF-alpha, the ...
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Anti inflammatory and arthritic effects of thiacremonone, a novel sulfurcompound isolated from garlic via inhibition of NF κB
... that 2-hydroxycinnamaldehyde, a snake venom toxin and melittin inhibit inflammatory responses and cancer cell growth through modification of sulfhydryl residues of NF-κB and regulatory proteins (p50 and p65 as ...
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Deficiency of iNOS-derived NO accelerates lipid accumulation-independent liver fibrosis in non-alcoholic steatohepatitis mouse model
... knockout/HFD mice livers at 48 weeks. (A) Liver samples were stained with α -SMA antibodies. Pericellular staining was visible only in iNOS−/− /HFD mice at 48 weeks. Scale bar, 50 μ m. (B) Liver IL-1, TGF- β , PDGF, ...
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Urate inhibits microglia activation to protect neurons in an LPS-induced model of Parkinson’s disease
... USA), inducible ni- tric oxide synthase (iNOS) (1:250), and glucose trans- porter member (Glut) 9 (1:800) (both from Abcam, Cambridge, MA, UK) and urate transporter (URAT) 1 (1:500, Proteintech, ...
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