infarcted myocardium
Extra-cellular expansion in the normal, non-infarcted myocardium is associated with worsening of regional myocardial function after acute myocardial infarction
... non-infarcted myocardium include increased loading conditions secondary to infarct ...normal myocardium undergoes expansion mainly due to increased wall stresses ...
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Coronary Flow Reserve in Non Infarcted Myocardium Predicts Long Term Clinical Outcomes in Patients Undergoing Percutaneous Coronary Intervention
... farcted myocardium far away from the infarcted myocardium was selected to ensure that there was no interaction between these ...the myocardium at baseline and after hyper- ...
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IGF-1 Expression in Infarcted Myocardium and MGF E Peptide Actions in Rat Cardiomyocytes in Vitro
... rat myocardium (vi- able myocardium was stained brick red, whereas infarcted myocardium failed to be stained with TTC; Figure ...injured myocardium and by the deviation of the ...
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Nanovector-based prolyl hydroxylase domain 2 silencing system enhances the efficiency of stem cell transplantation for infarcted myocardium repair
... Abstract: Mesenchymal stem cell (MSC) transplantation has attracted much attention in myocardial infarction therapy. One of the limitations is the poor survival of grafted cells in the ischemic microenvironment. Small ...
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Extra-cellular expansion in the normal, non-infarcted myocardium is associated with worsening of regional myocardial function after acute myocardial infarction
... non-infarcted myocardium include increased loading conditions secondary to infarct ...normal myocardium undergoes expansion mainly due to increased wall stresses ...
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Inhibition of Oct 3/4 mitigates the cardiac progenitor-derived myocardial repair in infarcted myocardium
... The myocardium has long been considered as a terminally differentiated organ because adult cardiomyocytes exhibit little proliferative activity relative to the fetal stage, and until recently it was seen as ...
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Over-expression of HO-1 on mesenchymal stem cells promotes angiogenesis and improves myocardial function in infarcted myocardium
... Heme oxygenase-1 (HO-1) is a stress-inducible enzyme with diverse cytoprotective effects, and reported to have an important role in angiogenesis recently. Here we investigated whether HO-1 transduced by mesenchymal stem ...
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Magnetic resonance hypointensive signal primarily originates from extracellular iron particles in the long-term tracking of mesenchymal stem cells transplanted in the infarcted myocardium
... (n=5) were transextracardially injected into the infarcted myocardium at ten distinct sites. In vivo CMR with T2 star weighted imaging-flash-2D sequence revealed a signal void correspond- ing to the initial ...
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A Fast pH-Switchable and Self-Healing Supramolecular Hydrogel Carrier for Guided, Local Catheter Injection in the Infarcted Myocardium
... After the initial studies in,vitro, we assessed the feasibility of intramyocardial delivery in a porcine model of myocardial infarction. In total, four injections of 0.2 cc were placed in one heart: two injections with ...
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Metformin induces apoptosis in mesenchymal stromal cells and dampens their therapeutic efficacy in infarcted myocardium
... infarction mouse model followed those described in our previous study [8]. The optimal oral metformin dosage for many diabetic patients is ~ 2 g/day. The human met- formin dosage of 20 mg/kg/day orally translates to an ...
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Molecular imaging of angiogenesis after myocardial infarction by 111In-DTPA-cNGR and 99mTc-sestamibi dual-isotope myocardial SPECT
... In conclusion, in this study, we designed and developed a molecular angiogenesis imaging probe that allowed us to sensitively visualise CD13 in the border zone of in- farcted myocardium and infarcted ...
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Local effects of acute cellular injury on regional myocardial blood flow
... As compared to blood flow 4 h after reperfusion, blood flow after 3 days of reperfusion was decreased in the anterior control region and in samples with 50% or less infarcted myocardium [r] ...
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“A Review on Novel Repurposing Candidates; Focus on Improved Therapeutic Strategies to Treat Myocardial Infarction” by Veena Kittur, Kesha Desai, Mohammad Azamthulla, India.
... the infarcted myocardium and reduce risk in left ventricular free wall rupture during the acute phase of MI also improves heart rate and systolic blood ...
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Sites and Mechanisms of Localization of Technetium 99m Phosphorus Radiopharmaceuticals in Acute Myocardial Infarcts and other Tissues
... This study was performed to elucidate the localization at the cellular level of technetium- 99m phosphorus ( 99m Tc-P) radiopharmaceuticals in acute myocardial infarcts and the mechanisms responsible for 99m Tc-P uptake ...
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Original Article Endothelial progenitor cell (EPC) transplantation improves myocardial infarction via up-regulation of vascular endothelial growth factor and gap junction protein connexin 43 in rats
... in infarcted myocardium and increased the myocardial vascular density, suggesting that the therapeutic effect of EPCs might be achieved through stimulation of ...
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Glucose and fatty acid metabolism in infarcted heart from streptozotocin-induced diabetic rats after 2 weeks of tissue remodeling
... Exposure to a high glucose medium or diabetes for short periods of time has been found to protect the heart against permanent ischemia. This may be due to the improved ventricular function, and reduced infarcted ...
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Original Article Astragaloside IV stimulates angiogenesis after myocardial infarction by regulating microRNA-21 expression
... in infarcted tissue and microvas- cular density around infarcted site was increased compared with control, moreover, AS-IV could up-regulate mRNA and protein expression of VEGF, p-AKT together with miR-21 ...
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Electrophysiological Mechanisms of Ventricular Fibrillation Induction
... to myocardium after a train of basic pacing stimuli ...the myocardium in this region had sufficiently recovered in time to be excited by the activation front which propagates from the directly excited ...
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A novel protective effect of erythropoietin in the infarcted heart
... The in vivo benefits of EPO extend beyond effects on ischemia because we found significant augmentation of cardiac contractility and relaxation, even when EPO was given at the time of MI. This enhanced function appears ...
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Cold acclimation alters the connective tissue content of the zebrafish (Danio rerio) heart
... In addition to changes in overall collagen content, we found that the hearts of cold-acclimated trout had significantly thinner collagen fibers and a decreased ratio of Type I:Type III collagen. In human hearts, ...
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