Infected-cells
Innate sensing of HIV infected cells
... Our observations raise intriguing questions about the nature of the cytosolic molecules recognizing HIV-infected cells. The cytosolic RLR (RIG-I-like receptors) helicases RIG-I and MDA5 may be involved in ...
15
Clones of infected cells arise early in HIV-infected individuals
... of infected cells in pre-ART ...HIV-infected cells involved the analysis of samples taken from individuals who had been on successful ART for ...the cells had clonally ...single ...
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Enzyme induction in virus-infected cells
... Polymeraze activity is stimulated by infection with Poxvirus Part 1, this thesis; Green and Pina, 1962 and Herpes simplex Keir and Gold, 1963 , but as yet it has not been established if [r] ...
180
Type I Interferon-Sensitive Recombinant Newcastle Disease Virus for Oncolytic Virotherapy
... NDV-infected cells. Although HuTu80 cells produced IFN- ␣ , levels of virus replication were comparable with and without IFN pretreatment ...these cells, as evidenced by the over- all ...
10
Role of Small Hydrophobic Protein of J Paramyxovirus in Virulence
... rJPV in infection in BALB/c mice. We also observed increased serum levels of TNF- ␣ in rJPV-ΔSH-infected animals at 3 dpi and 5 dpi. The increased serum levels of TNF- ␣ correlate with decreased lung viral loads ...
15
Generation and Efficacy Evaluation of a Recombinant Pseudorabies Virus Variant Expressing the E2 Protein of Classical Swine Fever Virus in Pigs
... PK-15 cells grown in 24-well culture plates were inoculated with each of the above viruses at an MOI of 10 and incubated on ice for 1 ...the infected cells were further incubated for 1 h at ...PK-15 ...
9
Stability properties and Hopf bifurcation for a Hepatitis B infection model with exposed state and humoral immunity-response delay
... uninfected cells, the infected, the virus and the B cells at time t, ...uninfected cells. Constant λ , k and g are birth rate of the uninfected cells, the virus and the B(t) ...
21
HIV-1 Nef Inhibits Ruffles, Induces Filopodia, and Modulates Migration of Infected Lymphocytes
... of cells (a few thousand per sample). We first analyzed NI Jurkat cells to define the parameters allowing the discrimination of circular cells, with no protrusions, from those expressing cellular ...
12
Feline Calicivirus: Recovery of Wild-Type and Recombinant Viruses after Transfection of cRNA or cDNA Constructs
... the cells using the Lipofectin method (Invitrogen Life Tech- nologies, Karlsruhe, ...the cells were further incubated in DMEM contain- ing 10% ...CRFK cells (isolated with guanidine isothiocya- nate ...
10
Virions and intracellular nucleocapsids produced during mixed heterotypic influenza infection of MDCK cells.
... Lane 1, Mock-infected cells; lane 2, cells infected with A/WSN/33; lane 3, cells doubly infected 1:1 with A/WSN/33 and B/Lee/40; lane 4, cells infected with B/Lee/40; lanes 5 to 9, the l[r] ...
5
Differential Role for TLR3 in Respiratory Syncytial Virus-Induced Chemokine Expression
... affect the responding cells or indirectly affect cells through the release of soluble mediators. Induction of some IRGs can occur by IFN signaling through the IFN- ␣ /  receptor and/or directly through the ...
8
Macromolecular Content of Inclusions Produced by a Canine Adenovirus
... The level of DNA polymerase activity in exponentially growing infected and uninfected whole cells was similar, but in cells in stationary phase the enzyme activity of infected cells was [r] ...
9
Dengue Virus Infected Dendritic Cells, but Not Monocytes, Activate Natural Killer Cells through a Contact Dependent Mechanism Involving Adhesion Molecules
... (NK) cells are a critical component of the innate immune system and provide early defense against viral infections (4, ...NK cells during the early stages of DENV infection ...NK cells displaying ...
14
Nonstructural 3 Protein of Hepatitis C Virus Modulates the Tribbles Homolog 3/Akt Signaling Pathway for Persistent Viral Infection
... (left) shows that TRIB3 and NS3 were colocalized in the cytoplasm of Jc1-infected cells, as indicated by yellow fluorescence. We also demonstrated the colocalization of TRIB3 and NS3 using HCV replicon ...
17
Adenosine N1-oxide inhibits vaccinia virus replication by blocking translation of viral early mRNAs.
... ANO effect on vaccinia virus DNA replication. Although ANO inhibited vaccinia virus replication, it remained to be determined which intracellular stage(s) of the virus life cycle was affected by the drug. Initial ...
7
Attenuation of Influenza A Virus mRNA Levels by Promoter Mutations
... from infected cells contains both mRNA and cRNA, which differ only at their termini, signals for both species of RNAs were expected in the same primer extension ...in cells infected with ...
8
Absence or Overexpression of the Varicella-Zoster Virus (VZV) ORF29 Latency-Associated Protein Impairs Late Gene Expression and Reduces VZV Latency in a Rodent Model
... lytically infected cells but in the cytoplasm of human neurons during latency (17, ...is infected with adenovirus which ex- presses ORF29, the protein is expressed in the cytoplasm; however, when ...
6
An Important Role for Mitochondrial Antiviral Signaling Protein in the Kaposi's Sarcoma-Associated Herpesvirus Life Cycle
... we infected cells as described previously (13, 14) with a recombinant KSHV express- ing GFP ...the cells via GFP ex- pression, as a marker of ...RIG-I-depleted cells compared to the control ...
10
Second-step transfer of bacteriophage T5 DNA: purification and characterization of the T5 gene A2 protein.
... We used uninfected cells, T5amH16d-infected cells, T5amH231-infected cells, and T5bi-infected cells as samples for two-dimensional gel electrophoresis.. We detected four spots on the gel[r] ...
10
Differing Effects of Herpes Simplex Virus 1 and Pseudorabies Virus Infections on Centrosomal Function
... Vero cells, a monkey cell line routinely used for alpha- herpesviruses, were mock infected or infected with 1 PFU/cell of HSV-1 for 3 h, 6 h, 12 h, 16 h, and 24 ...The cells were analyzed ...
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