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Infectious virus

Following acute encephalitis, Semliki Forest virus is undetectable in the brain by infectivity assays but functional virus RNA capable of generating infectious virus persists for life

Following acute encephalitis, Semliki Forest virus is undetectable in the brain by infectivity assays but functional virus RNA capable of generating infectious virus persists for life

... Forest virus (SFV) provides a well-characterised and tractable model of virus encephalitis ...which virus crosses the BBB to establish small perivascular foci of CNS infection and infectious ...

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The Hydrophobic Domain of Infectious Bronchitis Virus E Protein Alters the Host Secretory Pathway and Is Important for Release of Infectious Virus

The Hydrophobic Domain of Infectious Bronchitis Virus E Protein Alters the Host Secretory Pathway and Is Important for Release of Infectious Virus

... of infectious particles has been observed for other ...of infectious virus ...the virus, virions accu- mulated intracellularly, and infectious virus could not be re- covered ...

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Virus Replication in Enucleate Cells: Vesicular Stomatitis Virus and Influenza Virus

Virus Replication in Enucleate Cells: Vesicular Stomatitis Virus and Influenza Virus

... Vesicular stomatitis virus replicates normally in enucleate cells with the rate of production of infectious virus, the amount of virus-specific protein synthesis, and the type of protein[r] ...

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The Human Respiratory Syncytial Virus Matrix Protein Is Required for Maturation of Viral Filaments

The Human Respiratory Syncytial Virus Matrix Protein Is Required for Maturation of Viral Filaments

... M-null virus-infected cells is highly suggestive of an assembly process that was initiated but ...of virus-induced surface filaments, but the filaments are un- able to elongate in the absence of ...M-null ...

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Herpes simplex virus type 1 entry through a cascade of virus-cell interactions requires different roles of gD and gH in penetration.

Herpes simplex virus type 1 entry through a cascade of virus-cell interactions requires different roles of gD and gH in penetration.

... These results confirmed that i quantitative EM can differentiate between infectious and noninfectious samples, ii infectious virus entry proceeds at the cell surface through discernible [r] ...

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Recovery of infectious respiratory syncytial virus expressing an additional, foreign gene.

Recovery of infectious respiratory syncytial virus expressing an additional, foreign gene.

... RNA virus genomes, the frequency of mutation is estimated to be as high as 10 24 to 10 25 per site on average (reference 16 and references ...for virus replication and would be free to accumulate ...of ...

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Intracellular interference of tick-borne flavivirus infection by using a single-chain antibody fragment delivered by recombinant Sindbis virus.

Intracellular interference of tick-borne flavivirus infection by using a single-chain antibody fragment delivered by recombinant Sindbis virus.

... dsSIN virus system does have certain limitations. SIN virus infection can have varied effects on host DNA replication, RNA transcription, and trans- lation of mRNA in different vertebrate and invertebrate ...

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Feline Herpesvirus Infection in Fused Cultures of Naturally Resistant Human Cells

Feline Herpesvirus Infection in Fused Cultures of Naturally Resistant Human Cells

... When the cells with attached virus are subsequently fused with inactivated Sendai virus, FHV causes characteristic cytopathic effects, but no infectious virus can be recovered from the i[r] ...

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Inhibition of Sindbis virus maturation after treatment of infected cells with trypsin.

Inhibition of Sindbis virus maturation after treatment of infected cells with trypsin.

... Effect of trypsin treatment on production of infectious virus by Sindbis or VSV-infected BHK21 cells Type of cells Sindbis virus-infected Trypsin-treated, Sindbis virus- Virus yield PFU [r] ...

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The Composition of West Nile Virus Lipid Envelope Unveils a Role of Sphingolipid Metabolism in Flavivirus Biogenesis

The Composition of West Nile Virus Lipid Envelope Unveils a Role of Sphingolipid Metabolism in Flavivirus Biogenesis

... point, infectious virus release into the culture medium was already detected ...small virus-induced vesicles, referred to as vesicle packets (VPs) (5, 29, 43), as well as electron- dense virions ...

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Overexpression of the Rabies Virus Glycoprotein Results in Enhancement of Apoptosis and Antiviral Immune Response

Overexpression of the Rabies Virus Glycoprotein Results in Enhancement of Apoptosis and Antiviral Immune Response

... stomatitis virus (1), we were unable to rescue infectious viruses from RV full-length cDNA clones in which the position of the G gene was in closer prox- imity to the leader ...before infectious ...

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Dengue virus like particles mimic the antigenic properties of the infectious dengue virus envelope

Dengue virus like particles mimic the antigenic properties of the infectious dengue virus envelope

... into virus-like particles (VLPs) that are secreted from ...native virus, but are superior in terms of safety, and ease of production and purification ...Nile virus, Tick- borne encephalitis ...

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Insight into Poliovirus Genome Replication and Encapsidation Obtained from Studies of 3B-3C Cleavage Site Mutants

Insight into Poliovirus Genome Replication and Encapsidation Obtained from Studies of 3B-3C Cleavage Site Mutants

... of infectious virus pro- duction observed by the one-step growth analysis could be attributed to any step preceding production of infectious virus, for example, genome replication or ...

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Recovery of Infectious Rabbit Hemorrhagic Disease Virus from Rabbits after Direct Inoculation with In Vitro-Transcribed RNA

Recovery of Infectious Rabbit Hemorrhagic Disease Virus from Rabbits after Direct Inoculation with In Vitro-Transcribed RNA

... that infectious virus had indeed been generated following RNA inoculation in rabbits, crude extracts from these animals were assayed for infectivity in ...of infectious viral ...

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Selective response of gamma delta T-cell hybridomas to orthomyxovirus-infected cells.

Selective response of gamma delta T-cell hybridomas to orthomyxovirus-infected cells.

... influenza virus-infected mice responded in a reproducible way when cultured with influenza virus-infected ...vaccinia virus or Sendai ...influenza virus proteins, and so it is unlikely that ...

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Mutation in the matrix protein of Newcastle disease virus can result in decreased fusion glycoprotein incorporation into particles and decreased infectivity.

Mutation in the matrix protein of Newcastle disease virus can result in decreased fusion glycoprotein incorporation into particles and decreased infectivity.

... To determine whether the lower yield of infectious virus, especially at nonpermissive temperature, might be due to the production of fewer virus particles, or possibly to the production [r] ...

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Previously Infected and Recovered Chimpanzees Exhibit Rapid Responses That Control Hepatitis C Virus Replication upon Rechallenge

Previously Infected and Recovered Chimpanzees Exhibit Rapid Responses That Control Hepatitis C Virus Replication upon Rechallenge

... a virus stock was used for rechallenge that had no de- tectable sequence heterogeneity, greatly reducing the quasi- species problem one usually faces with natural ...ing virus in a rechallenged chimpanzee ...

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Convalescent plasma therapy and COVID-19

Convalescent plasma therapy and COVID-19

... The donor population will consist of adult (>18 years of age) who had a confirmed COVID-19 infection and were subsequently tested negative for the virus. The collection of plasma will be at least 28days from ...

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Host range, host specificity and hypothesized host shift events among viruses of lower vertebrates

Host range, host specificity and hypothesized host shift events among viruses of lower vertebrates

... necrosis virus (EHNV), first isolated from red- fin perch [36] and the first iridovirus associated with epizootic mortality in vertebrates [37], ranaviruses have caused epizooties in other fish species: sheatfish ...

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Mathematical Modeling and Analysis of Transmission of Rift Valley Fever

Mathematical Modeling and Analysis of Transmission of Rift Valley Fever

... the virus vertically and those that transmitted horizontally, and for one livestock ...the virus to hosts but not to their young ones, hence they considered it to be Culex ...remain infectious for ...

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