Inflammatory and autoimmune disease
Persistent Antinuclear Antibodies in Children Without Identifiable Inflammatory Rheumatic or Autoimmune Disease
... Clinical Profile of 24 Children With Musculoskeletal Pain, a Positive Antinuclear Antibody Test, and No Rheumatic Disease*. Case No[r] ...
6
Is atherosclerosis an autoimmune disease?
... of autoimmune diseases as well as in athe- rosclerosis. Systemic autoimmune diseases and atheros- clerosis share common pathogenic ...chronic inflammatory background mediated by the TLR and in- ...
5
Sphingosine kinase 2 in autoimmune/inflammatory disease and development of sphingosine kinase 2 inhibitors
... in autoimmune/inflammatory disease and to provide a rationale for targeting this ...promoting autoimmune disease, using, for instance, the IL-10 -/- mouse ...
24
Curcumin Ameliorate Diabetes type 1 Complications through Decreasing Pro-inflammatory Cytokines in C57BL/6 Mice
... diabetes autoimmune disease, Castro et al found that treatment with curcumin resulted in a significant delay in the onset of the ...prevents autoimmune diabetes by inhibiting leukocyte infiltration ...
8
Novel insight into Chronic Inflammatory Demyelinating Polineuropathy in APECED syndrome: molecular mechanisms and clinical implications in children
... A key question in autoimmune disease is the identity of inciting antigens. This question has been particularly difficult to address in CIDP because only a minority of patient sera samples contain PNS ...
5
Conventional and Nano-Based Therapy against Chronic Inflammatory Autoimmune Diseases
... in autoimmune disease triggers the inflammatory response resulting in recursion of immunologically competent cells to aggravate further the situation resulting in the intensification of the ...
8
Reactive oxygen species in organ-specific autoimmunity
... the autoimmune response but also in its amplification and spreading to novel epitopes, through the unmasking of cryptic ...specific autoimmune diseases (Hashimoto thy- roiditis, inflammatory bowel ...
11
How do autoimmune diseases cluster in families? A systematic review and meta-analysis
... s disease and each disease ...familial autoimmune disease is ...s disease; AS, ankylosing spondylitis; AITD, autoimmune thyroid disease; CD, celiac disease; CrD, ...
22
Th17 is involved in the pathogenesis of Bechet's disease via CCL20 CCR6 axis
... Rheumatoid arthritis (RA) is a representative autoimmune disease characterized by chronic and destructive inflammatory synovitis. The multiple cytokinesand cell surface molecules play a pivotal role ...
54
MicroRNAs in autoimmune disease
... systemic inflammatory autoimmune disease characterized by auto- antibodies against various self-antigens and damage to major organ ...SLE disease activity index (SLEDAI) and eight ...
7
Deciphering immune mechanisms in chronic inflammatory demyelinating polyneuropathies
... Chronic inflammatory demyelinating polyneuropathy (CIDP) is an autoimmune disease of the periph- eral nerves and nerve ...chronic autoimmune neuropathy in humans and is estimated to affect up ...
13
The autoimmune burden in juvenile idiopathic arthritis
... or approximately 1:300 to 1:80 children [13]. The Guidelines of the European Society for Paediatric Gas- troenterogy, Hepatology and Nutrition (ESPGHAN) suggest to test all asymptomatic patients affected by IDDM, Down ...
6
Human leukocyte antigens‑immunogenetics of neuromyelitis optica or Devic’s disease and the impact on the immunopathogenesis, diagnosis and treatment: a critical review
... and disease association studies in early 1970’s, the major histocompability complex (MHC) with its polymorphisms has been the “gold standard” and the primer genetic locus in attributing genetic burden for certain ...
7
Schizophrenia at a genetics crossroads: Where to now?
... but disease net- works are also likely to overlap (see figure ...involving autoimmune and inflammatory processes being identified across a range of common disorders (eg, CD, UC, T1D, Graves ...
6
Risk factors and outcome in patients with primary sclerosing cholangitis with persistent biliary candidiasis
... stenosis, inflammatory bowel disease, autoimmune hepatitis overlap syndrome, and number of times ERC was performed, biliary candidiasis was an independent risk factor for reduced survival (p = ...
9
Resistance to thyroid hormone β in autoimmune thyroid disease: a case report and review of literature
... Barkoff et al. [6] determined an increased prevalence of AITD among RTH-β patients, and postulated that suscepti- bility to AITD may be due to an underlying genetic dispos- ition. Our subjects have shown that in ...
5
Endocrine autoimmunity in Turner syndrome
... The observed incidence of thyroid autoimmunity in our study was 39.4%; 21.2% of patients were affected by clinical Hashimoto’s thyroiditis and 18.2% by preclinical autoimmune thyroiditis. This latter is ...
8
Can vagus nerve stimulation halt or ameliorate rheumatoid arthritis and lupus?
... It is proposed that reduced vagal tone triggers increased production of IL-6, TNF-a, MIF and HMGB1 by per- ipheral leukocytes, monocytes and macrophages; leads to an increase in sympathetic activity (due to the absence ...
7
HDAC Inhibition in Lupus Models
... positive inflammatory feedback loop initiated to induce production of cytokines and chemokines, which favors infiltration of inflammatory cells to target organs and facilitates autoantibody deposition in ...
9
← Return to Article Details Natural Support for Autoimmune and Inflammatory Disease
... ble-blind human study, a proprietary mixture of baicalin from Chinese skullcap and catechins, two anti-inflammatory flavonoids, was tested against a traditional nonsteroidal anti-inflammatory drug (NSAID), ...
10