Influenza A virus subtype H3N2
Influenza A H3N2 subtype virus NS1 protein targets into the nucleus and binds primarily via its C terminal NLS2/NoLS to nucleolin and fibrillarin
... Figure 2 The C-terminal end of the NS1 protein in H3N2 type influenza A viruses encode for a functional NoLS. (A) The N- and C-terminal fragments of the NS1 genes, encoding for amino acids 1 – 73 and 157 – ...
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Characterization of an H3N2 triple reassortant influenza virus with a mutation at the receptor binding domain (D190A) that occurred upon virus transmission from turkeys to pigs
... new subtype of influenza A viruses, H3N2 TR, emerged in pig population in the ...of H3N2 TR viruses between avian and mammalian ...one virus (A/turkey/Ohio/313053/04) transmitted ...
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Computationally Optimized Broadly Reactive Hemagglutinin Elicits Hemagglutination Inhibition Antibodies against a Panel of H3N2 Influenza Virus Cocirculating Variants
... influenza virus infection and therefore are unlikely to replace current licensed vaccine products that elicit neutralizing antibody ...of subtype-specific universal or broadly protective influenza vaccines ...
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Naturally Occurring Antibodies in Humans Can Neutralize a Variety of Influenza Virus Strains, Including H3, H1, H2, and H5
... H1N1 virus, but it did neutralize all other ...Caledonia/99 virus particles were coated onto an ...H3 subtype viruses ...against H3N2 (Aichi/68, Yamanashi/77, Kitakyushu/93, Panama/99) and ...
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Frequency of influenza H3N2 intra-subtype reassortment: attributes and implications of reassortant spread
... of influenza virus and has also been described as a part of a human T cell epitope [60, ...the virus, as well as drug suscepti- bility to zanamivir [62, ...sibly H3N2 NA 151 [64, ...
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Evaluation of Alere i Influenza A&B for Rapid Detection of Influenza Viruses A and B
... of influenza is important for infection control, as well as for patient ...i Influenza A&B is an isothermal nucleic acid amplification-based integrated system for detection and differentiation of ...
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The Avian-Origin PB1 Gene Segment Facilitated Replication and Transmissibility of the H3N2/1968 Pandemic Influenza Virus
... pandemic virus. An avian-origin H3 subtype virus (H3N?-Av) reassorted with a seasonal human H2N2 virus in undefined host species, producing the H3N2 reassortant virus with HA and ...
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Innate immune response to a H3N2 subtype swine influenza virus in newborn porcine trachea cells, alveolar macrophages, and precision-cut lung slices
... in influenza pathogenesis [49], we looked at the expression of SOCS transcripts in response to SIV in the three ...avian influenza (HPAI) H5N1 virus infection is linked to SOCS3 ...H1N1 virus ...
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Collectin-mediated antiviral host defense of the lung: evidence from influenza virus infection of mice.
... recent H3N2 strains are less virulent than earlier strains (44); however, the effects might be more subtle than would be required to influ- ence excess mortality ...certain H3N2 field strains isolated in ...
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Cross-Recognition of Avian H5N1 Influenza Virus by Human Cytotoxic T-Lymphocyte Populations Directed to Human Influenza A Virus
... pandemic influenza virus ...that virus-specific CTLs contribute to heterosubtypic immunity (6, 10, 16); sec- ondly, it was found in 1957 that individuals that had experi- enced documented infections ...
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Clinical and socioeconomic impact of different types and subtypes of seasonal influenza viruses in children during influenza seasons 2007/2008 and 2008/2009
... viral subtype and influenza B virus upon adjustment for age and ...of influenza A virus [18-20], this finding has been mainly attributed to the fact that younger children are at higher ...
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Development of an Immunochromatographic Assay Specifically Detecting Pandemic H1N1 (2009) Influenza Virus
... seasonal influenza viruses using MAbs Ab2 and Ab3. NPs of influenza A, B, and C viruses have important differences in their antigenicities that en- able them to be distinguished from one another but are ...
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Impact of Prior Seasonal H3N2 Influenza Vaccination or Infection on Protection and Transmission of Emerging Variants of Influenza A(H3N2)v Virus in Ferrets
... (IN/11) virus to naive animals. For comparison, a group of H3N2-immune ferrets re- ceived a homologous Perth/09 virus ...No virus shedding was detected from any of the six Perth/09-challenged ...
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Receptor Specificity of Influenza A H3N2 Viruses Isolated in Mammalian Cells and Embryonated Chicken Eggs
... on virus-host interactions in this ...5 virus and predomi- nated in the passage 9 virus (data not shown), suggesting that the Gly186Val/Ala198del combination is beneficial for growth in ...
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Novel H7N9 Influenza Virus Shows Low Infectious Dose, High Growth Rate, and Efficient Contact Transmission in the Guinea Pig Model
... for virus detection was re- moved, the head was then immersed in 10% buffered ...for influenza virus by immunohistochemistry ...A virus anti- bodies (mouse monoclonal antibody to NP protein, ...
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Reconstruction of H3N2 influenza virus based virosome in-vitro.
... V, influenza virosomes as an adjuvant have been efficiently used in the development of the Epaxal®, which has been on the market since 1994 for vaccination of Hepatitis A virus ...The influenza ...
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Origins and Evolutionary Dynamics of H3N2 Canine Influenza Virus
... (avian-origin H3N2 CIV) viruses, they pos- sess all the attributes to become—like pigs—another “mixing ves- sel” species, particularly if we consider that natural and experi- mental infections of dogs with human ...
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Development and implementation of the quality control panel of RT PCR and real time RT PCR for avian influenza A (H5N1) surveillance network in mainland China
... avian influenza virus H5N1, ...all influenza A (FluA) and H5 influenza subtyp- ing (H5) was performed using a fluorescently labeled TaqMan probe to enable continuous monitoring of amplicon ...
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Elicitation of Protective Antibodies against 20 Years of Future H3N2 Cocirculating Influenza Virus Variants in Ferrets Preimmune to Historical H3N2 Influenza Viruses
... season’s H3N2 strains, including sequence changes in the hemagglutinin (HA) due to egg adaptation ...these H3N2 influenza viruses were antigenically similar to clade ...and H3N2) and two influenza B ...
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Molecular Analysis of H7 Avian Influenza Viruses from Australia and New Zealand: Genetic Diversity and Relationships from 1976 to 2007
... avian influenza virus as a poultry and human disease ...avian influenza virus have oc- curred in Australian poultry production flocks located in the southeastern region of the ...avian ...
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