Inhalation toxicity
Investigation of acute dermal irritation/corrosion, acute inhalation toxicity and cytotoxicity tests for Nanobiocide®
... fed by filtering water ad libitum. The 10-week-old rats, weighing approximately 320g for the males and 225g for the females, were then separated into two groups (five rats in each group/sex): fresh-air control, test-dose ...
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Six-month low level chlorine dioxide gas inhalation toxicity study with two-week recovery period in rats
... the toxicity of the low-level, gas-phase CD, particularly the long-term toxicity, has not been well stu- ...few inhalation toxicity studies of CD gas, Paulet and Desbrousses [17-19] used high ...
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Subchronic inhalation toxicity of gold nanoparticles
... 90-day inhalation toxicity study was designed to identify possible adverse effects and deter- mine a LOAEL or ...Thus, inhalation exposure to gold nanoparticles provides the potential to separate the ...
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A statistical evaluation of the effects of gender differences in assessment of acute inhalation toxicity
... acute inhalation toxicity pro- vides data that can be used for this ...acute inhalation toxicity have not taken into account the possible influence on test per- formance of differences in the ...
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Comparative inhalation toxicity of multi-wall carbon nanotubes, graphene, graphite nanoplatelets and low surface carbon black
... the inhalation toxicity of the mentioned carbon-based nanomaterials, male Wistar rats were exposed head-nose to atmospheres of the respective materials for 6 hours per day on 5 consecutive ...black. ...
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An in vitro alveolar macrophage assay for predicting the short-term inhalation toxicity of nanomaterials
... Although the STIS allows reducing animal numbers, suffering, and distress as compared to the 28-day sub- acute inhalation toxicity study described in OECD Test Guideline (TG) 412 [12], it still uses ...
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An evaluation of the fixed concentration procedure for assessment of acute inhalation toxicity
... evident toxicity was already accepted as an endpoint for this existing test guideline, criticism of this endpoint was a major factor for the withdrawal of the FCP from the OECD work plan in 2007, due to concerns ...
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Chlorine Inhalation Toxicity From Vapors Generated by Swimming Pool Chlorinator Tablets
... We have presented two cases of serious respira- tory injury after brief exposure to vapors from solid. chlorine compounds[r] ...
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Application of short-term inhalation studies to assess the inhalation toxicity of nanomaterials
... Inhalation exposure to both coated nano-ZnO and micron-scale ZnO caused pulmonary inflammation, which was characterized by considerably increased PMN neutrophil and lymphocyte counts in the differ- ential cell ...
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Effects from a 90-day inhalation toxicity study with cerium oxide and barium sulfate nanoparticles in rats
... lated impaired macrophage clearance activity could therefore be suggested. Exacerbation of inflammation with ongoing exposure was also seen here by increasing inflammatory cell infiltrations with lymphocytes migrat- ing ...
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TOXICITY STUDY OF KUSHTHAVACHADI CHOORN INHALATION IN ALBINO MICE
... by inhalation in powder form to augment the labour process by enhancing uterine ...for inhalation purpose. It was necessary to carry out inhalation toxicity of this drug before using it in ...
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Bioaccessibility, bioavailability and toxicity of commercially relevant iron- and chromium-based particles: in vitro studies with an inhalation perspective
... low toxicity of the particles investigated in this study is in agreement with literature ...low toxicity is also in concordance with a recent systemic inhalation toxicity study on rats, ...
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Vaughan_unc_0153M_17043.pdf
... Despite the obvious differences in scale and differences in the nasal passages between mice and humans, they share key similarities that make mouse models a viable option for burn and inhalation injury. These ...
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Inhalation injury: epidemiology, pathology, treatment strategies
... smoke inhalation victims with high risk smoke expos- ...cobalt toxicity. Of studied agents, hydroxycobalamin has the smallest toxicity profile apart from allergic ...
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Pediatric inhalation injury
... Smoke inhalation injury causes a significant and often morbid damage to the lungs that can lead to pro- longed mechanical ventilation, increased mortality with concomitant injuries, and long-term pulmonary ...
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ASTHMA INHALATION DEVICES
... Asthma is treated mainly with inhaled medications in several forms, including the pressurized Metered Dose Inhaler (pMDI). Unfortunately, appropriate delivery of the chosen drug depends heavily on the patient’s inhaler ...
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Analytical methods to investigate occupational exposure to toxic elements and their species
... the toxicity of an ingested methylated arsenic compound in human urine from a dietary source will differ from that of a methylated arsenic compound in human urine as a result of inorganic arsenic ...
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Food hypersensitivity by inhalation
... Green bean hypersensitivity by inhalation has been reported in a homemaker [19]. She experienced asthma and rhinitis while boiling raw green beans, but had no symptoms upon ingestion of cooked green beans. ...
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Toxicity assessment of zinc oxide nanoparticles using sub-acute and sub-chronic murine inhalation models
... Development of clinical tolerance to repeated inhal- ation exposure to ZnO fumes from welding processes has been reported in clinical studies of metal fume fever [5] as well as in a study of zinc foundry workers [49] and ...
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REACH, animal testing, and the precautionary principle
... Abstract: Relatively little is known about the toxicity of the many chemicals in existence today. This has prompted European Union regulatory authorities to launch a major chemicals testing program, known as ...
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