Innate and adaptive immune system
Effect of buckminsterfullerenes on cells of the innate and adaptive immune system: an in vitro study with human peripheral blood mononuclear cells
... cytometry by measurement of the activation marker CD69, and secretion of T helper cell type 1 (TH1)- (interferon-gamma [IFN-γ], tumor necrosis factor beta [TNF-β]), TH2- (interleukin-5 [IL-5], -13, -10) and ...
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Tobacco smoking differently influences cell types of the innate and adaptive immune system—indications from CpG site methylation
... For semi-quantitative PCR (qPCR), total RNA of sepa- rated leukocytes was prepared by using peqGold RNA Pure (peqlab, Erlangen, Germany) according to the man- ufacturer’s instructions. The cDNA synthesis was carried out ...
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Effects of helium and air inhalation on the innate and early adaptive immune system in healthy volunteers ex vivo
... The study was approved by the ethical committee of the Academic Medical Centre, Amsterdam (www.trialregister. nl/ NTR2152) and was conducted in accordance with the International Conference on Harmonization on Good ...
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Balance between innate versus adaptive immune system and the risk of dementia: a population-based cohort study
... the immune system is challenging and focus of ongoing re- search, but recent work from the field of cancer research suggests that easily obtainable laboratory measurements may in fact capture their relative ...
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Inactivated Influenza Vaccine That Provides Rapid, Innate Immune System Mediated Protection and Subsequent Long Term Adaptive Immunity
... These findings highlight the benefits of using a TLR agonist to improve the utility and also to extend the spectrum of immunity induced by influenza split virus vaccines against homologous and heterologous subtypes. A ...
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The innate immune system in cystic fibrosis lung disease
... and immune cells and smooth muscle tone to antimicrobial activity, and may be protec- tive or deleterious in CF lung ...the innate immune system, the adaptive immune ...
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Toll-like receptor signaling in the innate immune system of zebrafish larvae
... of innate and adaptive immunity after fertilization (134, 135), which gives the possibility to study the host innate immune response to infection in the absence of adaptive ...
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Immune modulation of some autoimmune diseases: the critical role of macrophages and neutrophils in the innate and adaptive immunity
... phagocyte system; SDF-1: stromal derived factor-1; CXCR: C-X-C motif chemokine receptor; LXR: liver X receptor; IL: interleukin; MPS: mononuclear phagocyte system; M-CSF: macrophage-colony stimulating ...
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The Basic Immune Simulator: An agent-based model to study the interactions between innate and adaptive immunity
... simulated immune sys- tem eliminated the virally infected PCs and allowed regeneration to take place, is called an "immune ...simulated immune system failed to eliminate the virally ...
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Deciphering the genetic control of innate and adaptive immune responses in pig: a combined genetic and genomic study
... Labeling System (Promega, ...Clean-Up System (Pro- mega, USA) and 750 ng each of Cy3-labeled and Cy5- labeled cDNA targets were combined for slide hybridiza- ...
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Human Cytomegalovirus Particles Treated with Specific Antibodies Induce Intrinsic and Adaptive but Not Innate Immune Responses
... dysfunctional immune system, HCMV is a major cause of mor- bidity and ...the immune response against HCMV, including antigen presentation by macrophages, degranulation of innate natural killer ...
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Modulatory Effects Of North American Ginseng Extracts On Human Innate and Adaptive Immune Responses
... complement system. This plasma system is composed of more than 30 proteins that are produced by the liver in the absence of infection and circulate in the blood in their inactive form 2 ...complement ...
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Hepatitis C virus versus innate and adaptive immune responses: a tale of coevolution and coexistence
... host innate and adaptive immune responses and developed sophisticated ways to preempt, subvert, and antagonize ...the immune response in spontaneous and treat- ment-induced HCV ...
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Asthma as a chronic disease of the innate and adaptive immune systems responding to viruses and allergens
... the innate immune system positively stimulates the development of asthma came with the understanding that airway epithelial cells might also be a source of Th2 ...for innate immune ...
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Bordetella pertussis expresses a functional type III secretion system that subverts protective innate and adaptive immune responses
... secretion system (TTSS) to deliver effector proteins that interfere with cell function into host ...greater innate proinflammatory cytokine production in the lungs soon after challenge, and this corre- ...
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Interplays between Enterovirus A71 and the innate immune system
... antiviral innate immune ...antigen-specific adaptive immune responses ...antiviral innate immunity through targeting the PRR pathways and the JAK-STAT pathways [36, ...mammalian ...
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Skin innate immune system in psoriasis: friend or foe?
... how innate immunity can affect adaptive immune responses (32, 33) and to unravel the basis of the hyperresponsiveness of pre-psoriatic ...enhanced immune responses may also be considered in ...
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Deregulation of innate and adaptive immune responses in human papillomavirus infection and cancer
... UCHL1 alters the poly-ubiquitination of TRAF3 and NEMO TRAF3 ubiquitination is critical for type I IFN production and is a likely target for ubiquitin-modifying enzymes such as UCHL1. As the biochemical experiments to ...
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The role of leptin in innate and adaptive immune responses
... or innate immune ...the adaptive immune ...the innate immune system, causing inflammation of the injected joint ...
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HIV 1 Primarily Targets the Innate Immune System and Only Secondarily Modulates Adaptive Immune Cell Depletion
... Correlates of a promotional nature that are mainly characterized by a marked activation of lymphocyte sub- sets include the formulation for further persistence of cell injury within contextual reproduction of multiple ...
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