inner nuclear membrane
Cytomegalovirus Primary Envelopment Occurs at Large Infoldings of the Inner Nuclear Membrane
... herpesvirus nuclear egress, we rarely found capsids budding at the nuclear periphery but instead found them very frequently at the ...the inner nuclear membrane by a complex of M50/M53, ...
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Glycoprotein M of Herpes Simplex Virus 1 Is Incorporated into Virions during Budding at the Inner Nuclear Membrane
... the inner nuclear membrane (INM), but few studies have been undertaken to characterize the composition of these nascent ...integral membrane protein of herpes simplex virus 1 (HSV-1) that ...
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Herpes Simplex Virus Infection Induces Phosphorylation and Delocalization of Emerin, a Key Inner Nuclear Membrane Protein
... The inner nuclear membrane (INM) contains specialized membrane proteins that selectively interact with nuclear components including the lamina, chromatin, and ...of nuclear ...
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Autographa californica Nucleopolyhedrovirus Ac76: a Dimeric Type II Integral Membrane Protein That Contains an Inner Nuclear Membrane-Sorting Motif
... plasma membrane that is decorated with viral proteins by a strategy similar to other viruses that bud from the cell surface ...the inner nuclear membrane (INM) into the nucleoplasm (5, ...
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Genome-Wide Screen for Inner Nuclear Membrane Protein Targeting in Saccharomyces cerevisiae
... the nuclear interior and the cytoplasm occurs macromolecular ...through nuclear pores, proteinaceous aqueous chan- mechanisms that target/tether proteins to the ...Appropriate nuclear The ...
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Fate of the Inner Nuclear Membrane Protein Lamin B Receptor and Nuclear Lamins in Herpes Simplex Virus Type 1 Infection
... Nuclear-rim LBR-GFP is distorted in HSV-1-infected cells and partially redistributes to an altered ER. The lamin B receptor is a well-defined component of the INM. To examine the distribution of an LBR-GFP fusion ...
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Man1, an inner nuclear membrane protein, regulates vascular remodeling by modulating transforming growth factor β signaling
... The nuclear envelope (NE) is composed of outer and inner nuclear membranes (INM), nuclear lamina and nuclear pore ...outer nuclear membrane is directly continuous with the ...
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Distribution of Proteins at the Inner Nuclear Membrane Is Regulated by the Asi1 E3 Ligase in Saccharomyces cerevisiae
... Three putative RING finger E3 ligases have been implicated in INMAD in yeast: Doa10, Asi1, and Asi3. A broad range of Doa10 substrates have been described in the nucleus and ER, including the MATa2 transcriptional ...
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Baculovirus Data Suggest a Common but Multifaceted Pathway for Sorting Proteins to the Inner Nuclear Membrane
... pathway becomes a complex series of precisely positioned and interacting proteins that are not only responsive to the ele- ments in the main pathway but also sensitive to the environ- ment and global requirements of the ...
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Localization of Epstein-Barr virus envelope glycoproteins on the inner nuclear membrane of virus-producing cells.
... Fracture immunolabeling of B95-8 cells with BMA-17 monoclonal antibody: a dense and uniform labeling over the unfractured surface of a virus-producing cell; b incomplete fracture crack o[r] ...
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Effects of Inner Nuclear Membrane Proteins SUN1/UNC-84A and SUN2/UNC-84B on the Early Steps of HIV-1 Infection
... the nuclear lamina, such as lamin A (LMNA) (24, 25) and emerin (EMD) (26), and in the PNS via their carboxy-terminal SUN domains with the Klarsicht-ANC1-Syne-homology (KASH) domains of nesprin proteins anchored in ...
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Partial Functional Complementation of a Pseudorabies Virus UL25 Deletion Mutant by Herpes Simplex Virus Type 1 pUL25 Indicates Overlapping Functions of Alphaherpesvirus pUL25 Proteins
... Homologs of the UL25 gene product of herpes simplex virus 1 (HSV-1) are highly conserved among the Herpesviridae. However, their exact function during viral replication is unknown. Current evidence suggests that in the ...
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Herpesvirus Envelopment
... 16, who very clearly demonstrated the budding of herpes simplex virus from the inner nuclear membrane of HEp-2 cells, never observed enveloped particles in the cytoplasm, even as late as[r] ...
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Impairment of Nuclear Pores in Bovine Herpesvirus 1-Infected MDBK Cells
... the inner nuclear membrane is a frequently occurring event, we very rarely found budding by LTEM (Table ...the inner nuclear ...clear membrane than at the inner ...
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Role of the Endoplasmic Reticulum Chaperone BiP, SUN Domain Proteins, and Dynein in Altering Nuclear Morphology during Human Cytomegalovirus Infection
... in nuclear and cytoplasmic architec- ...the nuclear envelope is the nuclear lamina, a network of predominantly insoluble cellular proteins located on the nu- cleoplasmic side of the inner ...
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UNC 83 is a nuclear specific cargo adaptor for kinesin 1 mediated nuclear migration
... of nuclear migration in ...the nuclear envelope and connect the cytoskeleton with the nuclear lamina ...the inner nuclear membrane, where their N-termini interact with the ...
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Nuclear envelopathies: a complex LINC between nuclear envelope and pathology
... the inner surface of the nucleus, or located in the inner or outer nuclear ...for nuclear envelope components have been associated with rare human diseases affecting numerous different tissues ...
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Severe dystonia, cerebellar atrophy, and cardiomyopathy likely caused by a missense mutation in TOR1AIP1
... Results: We report on a boy born from consanguineous healthy parents, who presented at three years of age with rapidly progressing dystonia, progressive cerebellar atrophy, and dilated cardiomyopathy. We identified ...
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Intracellular transport of newly synthesized varicella-zoster virus: final envelopment in the trans-Golgi network.
... The radioautographic observations, taken as a whole, are consistent with the hypotheses that the initial viral envelope, acquired as nucleocapsids pass through the inner nuclear membrane[r] ...
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Autographa californica Multiple Nucleopolyhedrovirus EXON0 (ORF141) Is Required for Efficient Egress of Nucleocapsids from the Nucleus
... the inner nuclear membrane (20, 42). Nuclear egress is also affected by the US3 kinase, which appears to trigger the de-envelopment of primary enveloped capsids in the perinuclear region by ...
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