Insulin, Ins
Evaluation of the hypoglycaemic activity of Bauhinia monandra leaf in Alloxan diabetic rats and INS 1 insulin cells
... of insulin release from INS-1 cells (Table ...of insulin release at ...have insulin inhibitory activity, but it contains other compounds which have a different mode of activity other than ...
16
High-dose clevudine impairs mitochondrial function and glucose-stimulated insulin secretion in INS-1E cells
... INS-1E cells were cultured with different concentrations of clevudine for 4 weeks and the in vitro effects on mtDNA replication and translation were measured. Treatment with clevudine (10 μM to 1 mM) reduced the ...
9
Glucose stimulated insulin secretion correlates with changes in mitochondrial and cytosolic Ca2+ in aequorin expressing INS 1 cells
... during Insulin Secretion 2531 Figure ...of INS-1 EK-3 and C-29 cells stimulated with 20 mM ...loaded INS-1 EK-3 cells, where cells set and loaded as described in Meth- ods were exposed to three con- ...
16
Mechanisms of deformable nanovesicles based on insulin-phospholipid complex for enhancing buccal delivery of insulin
... using insulin as a model drug (IPC-DNVs) for buccal absorp- ...on insulin (INS-DNVs) and conventional nanovesicles based on insulin-phospholipid complex (IPC-NVs) as ...of insulin in ...
13
Effects of zinc supplementation and zinc chelation on in vitro β cell function in INS 1E cells
... 57°C); insulin, 5′-CGC TTC CTG CCC CTG CTG GC-3′ and 5′-CGG GCC TCC ACC CAG CTG CTC CA-3′ (annealing temperature 67°C); ZnT-3, 5′-TCC TCT TCT CTA TCT GCG CCC-3′ and 5′- TGT GCG GAG GCA ACG TGG TAA-3′ (annealing ...
12
Absence of the Wild-type Allele (192 Base Pairs) of a Polymorphism in the Promoter Region of the IGF-I Gene but Not a Polymorphism in the Insulin Gene Variable Number of Tandem Repeat Locus Is Associated With Accelerated Weight Gain in Infancy
... PATIENTS AND METHODS. We obtained genomic DNA from 768 children. Exclusion cri- teria were multiple births, gestational diabetes, maternal diabetes, gestational age ⬍ 37 weeks, ⬎ 42 weeks, or unclear, and any condition ...
8
Exercise metabolism in non obese patients with type 2 diabetes following the acute restoration of normoglycaemia
... the INS trial completed 30 min exercise without biochemical or symptomatic hypoglycaemia during exercise or the one-hour recovery after exercise, despite starting the exercise phase with a mean blood glucose of ...
9
Electrokinetic measurements of membrane capacitance and conductance for pancreatic cells
... for insulin secreting cells (primary β-cells and INS-1 insulinoma cells) determined using the methods of dielectrophoresis and ...for INS-1 cells, fall within the range expected for mammalian ...the ...
17
Hydrophobic ion pairing of an insulin-sodium deoxycholate complex for oral delivery of insulin
... free insulin 1 IU/kg was adminis- tered subcutaneously in the first group. Ins-SD-Comp-PLGA nanoparticles 20 IU/kg, free insulin 20 IU/kg, and saline were administered orally to the second group, the ...
8
Low glycaemic index diets improve glucose tolerance and body weight in women with previous history of gestational diabetes: a six months randomized trial
... towards insulin resistance [45], one would expect our study population to have higher fasting insulin ...have INS less than the ...fasting insulin values, of a small group (n=10) of Austrian ...
12
Hyposialylated IgG activates endothelial IgG receptor FcγRIIB to promote obesity induced insulin resistance
... caused insulin resistance in IgG-deficient mice via FcγRIIB, indicating that similar processes may be operative in T2DM in ...cell insulin transcytosis in culture and in ...preserved insulin ...
15
<p>Maturity-onset diabetes of the young (MODY): current perspectives on diagnosis and treatment</p>
... appropriate insulin release in the fetus and a normal birth ...fetal insulin secretion and a birth weight approximately 500 g higher than that of a baby who harbors the ...
10
Human serum proinsulin
... immunological identity with the human proinsulin standard. Partial tryptic digestion of the serum PLC yielded products with increased immunological reactivity as estimated with insulin as the standard. With larger ...
12
Interaction between obstructive sleep apnea and short sleep duration on insulin resistance: a large-scale study
... conclusions to asymptomatic patients, such as those res- iding in the community, is unclear. Fourth, though we carefully excluded participants who had medication which could affect sleep or insulin resistance, ...
11
Overweight among children and adolescent with type I diabetes mellitus: prevalence and associated factors
... intensive insulin therapy are likely to have a more flexible eating pattern, which could lead to increased risk of ...avoid insulin injections [26, ...
6
Dynamical models for diabetes: insights into insulin resistance and type 1 diabetes
... and insulin during a mixed meal and to assess the pathophysiology of glucose control during a standardized physiological ...fast insulin analogue basal rate, to be left unchanged for at least five hours ...
135
Self-reported risk factors and management strategies used by people with diabetes mellitus identified from the 1997 and 1998 NSW health surveys
... The survey data was accessed via the Health Outcomes Information and Statistical Toolkit (HOIST), a data warehouse maintained by the Centre for Epidemiology and Research, NSW Department of Health, and analysed using SAS ...
6
Optimal application of organic zinc in drinking water to improve the immune responses and to balance the hormones in broiler breeder hens
... the organic increase in serum IGF-1 (P <0.01) (Table 3-2). 200 ppm and 100 on organic diets were compared with 300 ppm of the organic decrease in serum cortisol was at the peak of production (Table 3-2). The amount ...
6
<p>Effect of Insulin-Regulated FOXC2 Expression in Adipocyte Differentiation and Insulin Resistance</p>
... when insulin resistance ...in insulin resis- tance by upregulating the level of ...4nM insulin minimized the effect of FOXC2 on GLUT4 ...as insulin induced the expression of endogenous ...
9
Neuropeptide Y level in paraventricular nucleus of experimental diabetic rats: correlation with sympathetic activity and body weight
... In conclusion, we strongly believe that the role of NPY in different types of diabetes varies. In the presence of a high level of NPY, type 1 (insulin dependent) diabetes is associated with increased sympathetic ...
5