Insulin-Like Growth Factor I
Circulating levels of insulin like growth factor I (IGF I) correlate with disease status in leprosy
... The low circulating levels of IGF-I/IGFBP-3 found in nonreactional LL patients (~75% with below-normal levels) were in parallel with those found in other critical illnesses like sepsis [25,26]. It is known ...
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Protease resistant form of insulin like growth factor binding protein 5 is an inhibitor of insulin like growth factor I actions on porcine smooth muscle cells in culture
... IGFs are pleiotrophic mitogens for porcine smooth muscle cells (pSMC) in culture. The effects of IGFs on cells are modulated by various insulin-like growth factor-binding proteins (IGFBP). ...
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Effects of growth hormone and insulin like growth factor I on rabbit proximal convoluted tubule transport
... that growth hormone has no direct effect on PCT transport. In the PCT, IGF-I stimulates phosphate transport specifically and acts via both basolateral and apical ...
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Effects of recombinant human insulin like growth factor I on glomerular dynamics in the rat
... recombinant human insulin-like growth factor I (rhIGF-I) increases GFR and renal plasma flow (RPF) in rats. Glomerular micropuncture studies were carried out in 14 nonstarved ...
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Alveolar macrophages release an insulin like growth factor I type molecule
... purification of medium conditioned by activated alveolar macrophages using ion exchange and gel filtration chromatography revealed an IGF-I molecule as detected by an anti-IGF-I polyclonal antibody and that ...
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Interactions between insulin like growth factor I (IGF I) and the renin angiotensin system in follicular growth and ovulation
... uration, and ovulation (24, 28, 41, 42). The increase in intrafol- licular PA activity observed in IGF-I–treated ovaries was al- most identical to that observed previously in mature follicles following exposure to ...
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A reappraisal of the role of insulin like growth factor I in the regulation of human hematopoiesis
... progenitor cells. Functional significance of the latter possibility was tested by exposing CD34+ cells to IGF-IR antisense oligodeoxynucleotides. Colony formation was unaffected by oligodeoxynucleotide disruption of ...
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High affinity insulin binding to an atypical insulin like growth factor I receptor in human breast cancer cells
... unlabeled insulin and IGF-I. Further, the B29-MAB-125I-insulin photoprobe cross-linked to MCF-7 membranes was strongly immunoprecipitated by ...with insulin-Affi-gel followed by insulin ...
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Human conditions of insulin like growth factor I (IGF I) deficiency
... and insulin, IGF-I is a nat- ural peptide already produced in humans, what facilitates the elucidation of possible secondary effects due to rhIGF-I ...the insulin like action of ...
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Comparison of the effects of growth hormone and insulin like growth factor I on substrate oxidation and on insulin sensitivity in growth hormone deficient humans
... Insulin-like growth factor-I (IGF-I) is considered to be the mediator of the growth-promoting effects of growth hormone ...elevated insulin and glucose ...
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Ovine placental lactogen and insulin like growth factor I : a study of their biological actions and potential to enhance animal production : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Animal Science at Massey University, Palmerston North, New Zealand
... little growth promoting effect in well-fed ...(P<O. I ) GH secretion in response to a GRF load, but significantly ...on growth rate of the sheep although it did increase nitrogen digestibility of ...
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Effects of insulin like growth factor I on glucose tolerance, insulin levels, and insulin secretion
... Insulin-like growth factor-I (IGF-I) and insulin interact with related receptors to lower plasma glucose and to exert mitogenic ...of insulin and C-peptide in ...
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Muscle growth and flesh quality of farmed Atlantic halibut (Hippoglossus hippoglossus) in relation to season of harvest
... width of the Z-band is known to vary with different types of muscle tissue in both mammals (Eisenberg, 1983) and fish (Luther, 1991), with fast striated muscle having a smaller Z-band width compared to slow muscle. When ...
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Insulin like growth factor I in acute subarachnoid hemorrhage: a prospective cohort study
... To the best of our knowledge, this is the first study to evaluate the behavior of IGF-I in the acute phase of aSAH, and to combine it with GOS and HRQoL assess- ment at three months. According to our study, serum ...
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Differential regulation of insulin like growth factor binding protein secretion from human decidual cells by IGF I, insulin, and relaxin
... Several growth hormone-independent 25-31,000 kD insulin-like growth factor binding proteins (IGF-BPs) have been identified in plasma, extravascular fluids, and various cell- conditioned ...
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Insulin like growth factors and insulin like growth factor binding proteins in mammary gland function
... There is evidence that IGFBPs can regulate apoptosis not only via sequestration of IGFs, but independently of IGFs. In some cell systems, IGFBPs can induce apoptosis; for example, IGFBP-3 induces apoptosis in MCF-7 ...
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IGF-1 and VEGF in Saliva and Its Relation with CVMI Stages in Determining the Skeletal Maturity
... according to quantitative cervical vertebral maturation (QCVM) of adolescents. The samples consisted of 87 adolescents (32 boys and 55 girls) age ranging from 8 to 18 years. Lateral cephalograms and hand wrist films were ...
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Growth factor expression in aorta of normotensive and hypertensive rats
... platelet-derived growth factor (PDGF) B chain and PDGF A chain, insulin-like growth factor (IGF)-I and IGF-II, endothelial cell growth factor (ECGF), basic ...
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Insulin like growth factor I stimulates lipid oxidation, reduces protein oxidation, and enhances insulin sensitivity in humans
... of insulin-like growth factor I (IGF-I) on fuel oxidation and insulin sensitivity, eight healthy subjects were treated with saline and recombinant human (IGF-I (10 ...
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Changes in pain and insulin like growth factor 1 in fibromyalgia during exercise: the involvement of cerebrospinal inflammatory factors and neuropeptides
... Type I errors, the upper limit of number of false significances was calculated by the following formula: (number of tests - number of significant tests on the level of a) × ...
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