insulin-like peptide 5
Ovarian expression of Insulin Like peptide 3 (INSL3) and its receptor (RXFP2) during development of bovine antral follicles and corpora lutea and measurement of circulating INSL3 levels during synchronized estrous cycles
... torchidism (5, 6). INSL3 signals through a G protein-cou- pled receptor known as relaxin family peptide receptor (RXFP)2 (7), which is closely related to the relaxin recep- tor RXFP1. Mice lacking RXFP2 ...
10
Crosstalk between FXR and TGR5 controls glucagon-like peptide 1 secretion to maintain glycemic homeostasis
... glucagon-like peptide 1 (GLP-1) to potentiate insulin secretion in pancreatic β cells, leading to decreased blood glucose level in enteroendocrinal cell lines and animal models ...
7
Brain glucagon like peptide–1 increases insulin secretion and muscle insulin resistance to favor hepatic glycogen storage
... ameliorates insulin sensitivity in fat-fed diabetic ...muscle insulin receptor when Ex9 was infused into the ...impaired insulin action and glucose tolerance following high-fat ...plasma ...
11
An insulin like peptide regulates size and adult stem cells in planarians
... To test if insulin/IGF signaling in S. mediterranea might be re- sponsible for regulating adult size homeostasis, we created dsRNA feeding vectors for ilp-1 and inr-1. Then, according to established RNA ...
9
Identification and functional characterisation of a Schistosoma japonicum insulin like peptide
... Polyclonal antibodies were raised against the SjILP fusion protein in 8 weeks old female Balb/c mice. Briefly, five mice were immunised three times each with 25 μg recombinant protein adjuvanted with Quil A (Superfos, ...
12
Chitosan oligosaccharide improves the therapeutic efficacy of sitagliptin for the therapy of Chinese elderly patients with type 2 diabetes mellitus
... improving insulin sensitivity, lipid profile, adiponectin levels, and glucagon-like peptide 1 and reducing side effects, insulin resistance, HbA1c, body mass index, resistin, tumor necrosis ...
12
<p>Sitagliptin Increases Beta-Cell Function and Decreases Insulin Resistance in Newly Diagnosed Vietnamese Patients with Type 2 Diabetes Mellitus</p>
... – 5 There have been two incretin-related therapies for patients with T2D, namely glu- cagon-like peptide-1 agonists and dipeptidyl peptidase-IV ...
9
Effects of insulin analogs and glucagon-like peptide-1 receptor agonists on proliferation and cellular energy metabolism in papillary thyroid cancer
... The PTC cell line IHH-4 was obtained from the Japanese Collection of Research Bioresources, Japan. The PTC cell line BCPAP was purchased from the DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH (German ...
11
Insulin like growth factor I improves glucose and lipid metabolism in type 2 diabetes mellitus
... and insulin resistance cause vascular disease in type 2 diabetes ...or insulin enhance ...human insulin- like growth factor-I (rhIGF-I) caused normoglycemia in insulin-resistant ...
9
Article: Measurement of circulating insulin-like peptide 3 and testosterone concentrations in pre-pubertal, tropical male goats
... A competitive EIA was developed to quantify INSL3 by modifying the previously described procedures for goats (Hannan et al., 2016) and cattle (Kawate et al., 2011). Previously developed INSL3 EIA was modified by omitting ...
6
Glucagon-like peptide-1 enhances cardiac L-type Ca2+ currents via activation of the cAMP-dependent protein kinase A pathway
... glucagon-like peptide isolated from the intestine of the eel, Anguilla japonica[21] with a structure similar to that of oxynto- modulins has shown an inotropic effect via stimulation of Ca 2+ influx and a ...
9
Trithorax regulates systemic signaling during Drosophila imaginal disc regeneration
... independent experiments, control n=325 wings, trx E2 /+ n=270 wings, rn>puc n=114 wings. (D,E) Phosph-JNK immunostaining in control (D) and trx E2 /+ (E) R24 discs. (F) Quantification of phospho-JNK staining in the ...
12
Muscle growth and flesh quality of farmed Atlantic halibut (Hippoglossus hippoglossus) in relation to season of harvest
... Matrix Metalloproteinases (MMPs) are a large family consisting of at last 26 calcium- dependent zinc-containing metalloendopeptidases members, divided into 5 distinct classes (collagenases, gelatinases, ...
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Disruption of insulin signalling affects the neuroendocrine stress reaction in Drosophila females
... in 5- to 6-day-old females (wild-type strain Canton-S), whereas JH degradation measured in vivo is significantly lower in young than in mature Canton-S females (Gruntenko et ...
9
Relaxin like peptides in male reproduction: a human perspective
... To date, only H2 relaxin has been trialled in a clinical/ therapeutic context and then for indications generally unre- lated to male reproduction (Tietjens and Teerlink, 2016). Importantly, H2 relaxin has passed ...
12
Marked changes in neuropeptide expression accompany broadcast spawnings in the gastropod Haliotis asinina
... neuro- peptide genes - whitnin, haliotid growth associated peptide (HGAP), and molluscan insulin-related peptide (MIP) - vary in expression in the cerebral and pleuropedal ganglia (here- after ...
17
Insulin-Like Growth Factor Family and Combined Antisense Approach in Therapy of Lung Carcinoma
... days 5 and 25 of in vitro cell growth by using a mouse monoclonal antibody directed against native rat IGF- II and a secondary goat anti-mouse IgG serum conju- gated to horseradish ...
9
Targeting insulin-like growth factor axis in hepatocellular carcinoma
... (< 5 pg/ml) before treatment with CP- 75871 were more likely to suffer fatal events within 60 days of ...the insulin-like growth factor ...
11
Building Muscle: The Role of Insulin-Like Growth Factor Binding Protein-6 and Insulin-Like Growth Factors in the Differentiation of Placental Mesenchymal Stem Cells into Skeletal Muscle
... The promise of using stem cells in treating diseases is becoming closer to be used in the clinic (29, 30). Still, understanding the niche factors and their influence on stem cell proliferation and differentiation in ...
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Genomics of tick reproduction and development
... ITPs have been shown to play a role is osmoregulation while closely related sequences such as CHHs can have different physiological functions. DvITP contains the CHH motif but the phylogenetic separation of CHHs and ITPs ...
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