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insulin lispro

Insulin Lispro Lowers Postprandial Glucose in Prepubertal Children With Diabetes

Insulin Lispro Lowers Postprandial Glucose in Prepubertal Children With Diabetes

... human insulin injected subcutaneously typically results in serum insulin levels that peak later and remain elevated longer than those observed after pancreatic insulin ...human insulin ...

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Delving Deep into the Structural Aspects of the BPro28-BLys29 Exchange in Insulin Lispro: A Structural Biophysical Lesson

Delving Deep into the Structural Aspects of the BPro28-BLys29 Exchange in Insulin Lispro: A Structural Biophysical Lesson

... of insulin in 1921, a medical triumph which led to it being one of the most intensely studied molecules [1, 2, 3, 4, 5, ...human insulin to make it more suitable for subcutaneous administration, various ...

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Cumulative clinical experience with use of insulin lispro: critical appraisal, role in therapy, and patient considerations

Cumulative clinical experience with use of insulin lispro: critical appraisal, role in therapy, and patient considerations

... rapid-acting insulin analogs, of which insulin lispro was the first to become commercially ...to insulin lispro. The clinical characteristics of insulin lispro are ...

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Insulin Lispro - A Review

Insulin Lispro - A Review

... regular insulin, insulin lispro achieved peak concentrations that were two times higher in less than half the time 4 ...of insulin was ...of insulin lispro is that the time ...of ...

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Clinical use and efficacy of biphasic insulin lispro 50/50 in people with insulin treated diabetes-A nationwide evaluation of clinical practice

Clinical use and efficacy of biphasic insulin lispro 50/50 in people with insulin treated diabetes-A nationwide evaluation of clinical practice

... the insulin regimen used prior to Humalog ...bolus insulin regimen (Figure ...here). Insulin doses increased following conversion to Humalog Mix50, irrespective of the types of insulin used ...

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Insulin lispro low mixture twice daily vs basal insulin glargine once daily and prandial insulin lispro once daily as insulin intensification strategies in patients with type 2 diabetes: Latin American subpopulation analysis of a randomized trial

Insulin lispro low mixture twice daily vs basal insulin glargine once daily and prandial insulin lispro once daily as insulin intensification strategies in patients with type 2 diabetes: Latin American subpopulation analysis of a randomized trial

... premixed insulin regimen with a once-daily basal insulin plus once-daily prandial insu- lin regimen in patients with T2DM not adequately controlled on insulin glargine with metformin and/or ...on ...

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Continuous glucose monitoring with Humalog Mix 25 versus Humalog Mix 50, twice daily: A comparative pilot study -Results from the Jikei-EValuation of insulin Lispro mixture on pharmacodynamics and glycemic VariancE (J-EVOLVE) study

Continuous glucose monitoring with Humalog Mix 25 versus Humalog Mix 50, twice daily: A comparative pilot study -Results from the Jikei-EValuation of insulin Lispro mixture on pharmacodynamics and glycemic VariancE (J-EVOLVE) study

... In conclusion, our study clearly demonstrates that a twice-daily Mix 25 regimen provides superior overnight glycemic control compared to twice-daily Mix 50 in Japa- nese patients with type 2 diabetes. However, the twice- ...

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Clinical Considerations for Insulin Pharmacotherapy in Ambulatory Care, Part Two: Review of Primary Literature and an Evidence-Based Approach for Treatment

Clinical Considerations for Insulin Pharmacotherapy in Ambulatory Care, Part Two: Review of Primary Literature and an Evidence-Based Approach for Treatment

... prandial insulin aspart boluses compared with full basal-bolus therapy (FullSTEP study): a randomised, treat-to-target clinical ...Prandial-basal insulin regimens plus oral antihyperglycaemic agents to ...

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Systematic literature review of use of blood glucose monitoring in phase III clinical studies of insulin analogs

Systematic literature review of use of blood glucose monitoring in phase III clinical studies of insulin analogs

... of insulin are ultimately linked together for an effective and safe ...of insulin has been established in phase III clinical studies ...of insulin treatment, it provides additional arguments for the ...

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Relapsing insulin-induced lipoatrophy, cured by prolonged low-dose oral prednisone: a case report

Relapsing insulin-induced lipoatrophy, cured by prolonged low-dose oral prednisone: a case report

... subcutaneous insulin infusion with a porta- ble insulin pump using human regular insulin, without any adverse ...2004, insulin lispro (Humalog ® , Eli Lilly Deutschland, Bad Homburg, ...

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Conformational flexibility of the pharmacologically important insulin analogues

Conformational flexibility of the pharmacologically important insulin analogues

... the insulin drugs is of great importance for the treatment of diabetes ...the insulin receptor and activating specific biological ...important insulin ana- logues—insulin lispro, ...

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Is Postprandial Glucose Control Important? Is It Practical In Primary Care Settings?

Is Postprandial Glucose Control Important? Is It Practical In Primary Care Settings?

... new insulin preparations and oral thera- pies may provide part of the solution to this ...Rapid-acting insulin analogs, such as insulin aspart (Novolog) and insulin lispro, produce ...

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Effects of Twice Daily Injections of Premixed Insulin Analog on Glycemic Control in Type 2 Diabetic Patients

Effects of Twice Daily Injections of Premixed Insulin Analog on Glycemic Control in Type 2 Diabetic Patients

... Premixed insulin is effective to improve glycemic control; however, clinicians may be less likely to know which premixed insulin is appropriate for which ...premixed insulin lispro on glycemic ...

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Assessment of a Case of Immediate Type Allergy against Human Insulin in a Type 2 Diabetic Patient and Allergic Reactions to Human Insulin in Japan

Assessment of a Case of Immediate Type Allergy against Human Insulin in a Type 2 Diabetic Patient and Allergic Reactions to Human Insulin in Japan

... evaluate insulin allergy, intradermal skin tests were performed with human insulin (Humulin R), insulin lispro (Humalog), insulin aspart (NovoRapid), insulin glulisine (Apidra), ...

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Pharmacokinetics and pharmacodynamics of insulin analogs in special populations with type 2 diabetes mellitus

Pharmacokinetics and pharmacodynamics of insulin analogs in special populations with type 2 diabetes mellitus

... “insulin lispro,” “insulin aspart,” “insulin glulisine,” “insulin glargine,” “insulin detemir,” “regular human insulin,” “neutral protamine Hagedorn,” and ...each ...

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Extracts from Salvia Nelumbinis naturalis alleviate hepatosteatosis via improving hepatic insulin sensitivity

Extracts from Salvia Nelumbinis naturalis alleviate hepatosteatosis via improving hepatic insulin sensitivity

... regulator insulin signaling. SOCS3 has been shown interfering insulin signaling by competitively binding to the InsR, affecting IRS phosphorylation [17], or promoting ubiquitin-mediated IRS degradation ...

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Fasting insulin sensitivity indices are not better than routine clinical variables at predicting insulin sensitivity among Black Africans: a clamp study in sub-Saharan Africans

Fasting insulin sensitivity indices are not better than routine clinical variables at predicting insulin sensitivity among Black Africans: a clamp study in sub-Saharan Africans

... basal insulin secretion in people of African ancestry [17], which may have clouded the relationship between these indices and clamp-derived ...clamp-derived insulin sensitivity index and HOMA-IR ...between ...

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No Dose Response Relationship in the Effects of Commonly Consumed Sugars on Risk Factors for Diabetes across a Range of Typical Human Consumption Levels

No Dose Response Relationship in the Effects of Commonly Consumed Sugars on Risk Factors for Diabetes across a Range of Typical Human Consumption Levels

... [22] Stanhope, K.L., Schwarz, J.M., Keim, N.L., Griffen, S.C., Bremer, A.A., Graham, J.L., Hatcher, B., Cox, C.L., Dya- chenko, A., Zhang, W., McGahan, J.P., Seibert, A., Krauss, R.M., Chiu, S., Schaefer, E.J., Ai, M., ...

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An overview of insulin pump therapy: appropriate use of an expensive resource

An overview of insulin pump therapy: appropriate use of an expensive resource

... and insulin dose diary, which should be sent to the dietitian every few ...patient’s insulin-to-carbohydrate ratio and his or her diurnal variation, and to eliminate common ...

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Insulin resistance and hypersecretion in obesity  European Group for the Study of Insulin Resistance (EGIR)

Insulin resistance and hypersecretion in obesity European Group for the Study of Insulin Resistance (EGIR)

... analysis. Insulin hypersecretion, de- fined by the same statistical criterion as used for insulin resis- tance, was significantly more prevalent than insulin resistance in the obese group as a whole ...

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