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Insulin Resistance

Inflammation and insulin resistance

Inflammation and insulin resistance

... Over a hundred years ago, high doses of salicylates were shown to lower glucose levels in diabetic patients. This should have been an important clue to link inflammation to the pathogenesis of type 2 diabetes (T2D), but ...

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The Prevalence of Insulin Resistance in Patients with Psoriasis

The Prevalence of Insulin Resistance in Patients with Psoriasis

... In this study, the insulin resistance frequency was 46.4% and 39.1% of controls although this value in patients with psoriasis is greater than the control group but this difference was not statistically ...

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Metabolic syndrome and insulin resistance in migraine

Metabolic syndrome and insulin resistance in migraine

... with insulin resis- ...and insulin; both of which remain elevated after glucose loading suggesting insulin resistance ...controls. Insulin sensitivity is sig- nificantly altered in ...

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The role of fatty acids in insulin resistance

The role of fatty acids in insulin resistance

... with insulin resistance ...of insulin resistance in the ...sulin resistance in the liver, they are strongly related to insulin resistance in the muscle ...overcome ...

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Four‑Stage Evolution of Diabetes or Whole Body Insulin Resistance (WBIR): Debunking of the Lipid‑Induced Insulin Resistance (LIIR) and Proposing of the Glycation‑Induced Insulin Resistance (GIIR)

Four‑Stage Evolution of Diabetes or Whole Body Insulin Resistance (WBIR): Debunking of the Lipid‑Induced Insulin Resistance (LIIR) and Proposing of the Glycation‑Induced Insulin Resistance (GIIR)

... yet. Insulin resistance (IR) plays a central role in development of ...muscle insulin resistance (MIR), subcutaneous adipose insulin resistance (s-AIR), visceral adipose ...

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Diabetes mellitus in the elderly: insulin resistance and/or impaired insulin secretion?

Diabetes mellitus in the elderly: insulin resistance and/or impaired insulin secretion?

... and insulin resistant than young individuals, and many of them will develop type 2 ...reduce insulin sensitivity. Insulin resistance in elderly people appears to predominate in skeletal ...

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Signaling pathways in insulin action: molecular targets of insulin resistance

Signaling pathways in insulin action: molecular targets of insulin resistance

... meal. Insulin regulates glucose homeostasis at many sites, reducing hepatic glucose output (via decreased gluconeogenesis and glycogenolysis) and increasing the rate of glucose uptake, primarily into striated ...

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Acanthosis nigricans: a flag for insulin resistance

Acanthosis nigricans: a flag for insulin resistance

... Objectives: Acanthosis nigricans refers to the velvety, black hyperpigmentation seen in the flexures. It is a cutaneous marker for insulin resistance (IR), some metabolic disorders and rarely malignancy. ...

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Fertility. Impact of Insulin Resistance

Fertility. Impact of Insulin Resistance

... bicycle sessions per week, reduced waist circumference (WC) significantly even when only smaller amounts of total body weight were lost. Reduced WC is a result of losing intra‑abdominal fat (as opposed to subcutaneous ...

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Obesity, Insulin Resistance and Cancer Risk

Obesity, Insulin Resistance and Cancer Risk

... A metabolic syndrome can be described as a complex of risk factors for cancer including obe- sity, insulin resistance, inflammation, and diseases such as diabetes and atherosclerosis. Additional studies are ...

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The role of endothelial insulin signaling in the regulation of vascular tone and insulin resistance

The role of endothelial insulin signaling in the regulation of vascular tone and insulin resistance

... in insulin-regu- lated glucose ...of insulin action in endothelial function, we have generated a vascular endothelial cell IR knockout (VENIRKO) mouse using the Cre-loxP ...of insulin sensitivity to ...

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Hyperglycaemic preterm neonates exhibit insulin resistance and low insulin production

Hyperglycaemic preterm neonates exhibit insulin resistance and low insulin production

... for insulin and C-peptide and was measured in temporal association with ...the insulin-treated neonates had ...the insulin-treated hyperglycaemic neonates ...lower insulin production. ...

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Intramyocellular lipid kinetics and insulin resistance

Intramyocellular lipid kinetics and insulin resistance

... of insulin resistance, the content of signaling molecules, including long chain acyl CoA (LCACoA), diacylglycerol (DAG) and ceramides are increased in skeletal muscle ...with insulin signaling via ...

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A Review of Contemporary Markers of Insulin Resistance

A Review of Contemporary Markers of Insulin Resistance

... As far back as 1979, Turner RC et al came up with the finding that insulin and IR were associated with DM. They also established that the degree of basal hyperglycemia in diabetes was a reflection of the degree of ...

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Inflammatory Mechanisms in the Regulation of Insulin Resistance

Inflammatory Mechanisms in the Regulation of Insulin Resistance

... Insulin resistance (IR) plays a key role in the pathophysiology of obesity-related diseases such as type 2 diabetes and nonal- coholic fatty liver ...

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Fructose, insulin resistance, and metabolic dyslipidemia

Fructose, insulin resistance, and metabolic dyslipidemia

... the insulin resistant state developed upon fructose feeding is also associated with stimulated hepatic VLDL ...body insulin resistance [100] and reduced hepatic insulin sensitivity ...induced ...

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Aspirin and Blood Glucose and Insulin Resistance

Aspirin and Blood Glucose and Insulin Resistance

... of insulin resistance in type 2 DM. Decreased hepatic insulin sensitivity may lead to increased hepatic gluconeogenesis, post-prandial hyper- insulinemia and increased formation of triglycerides ...

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Prevalence of insulin resistance in cirrhosis of liver

Prevalence of insulin resistance in cirrhosis of liver

... Methods: One Hundered (100) non-diabetic patients of liver cirrhosis considering the inclusion and exclusion criteria and visiting both indoor and outpatient department of medicine, SGRDIMSAR were included in the study. ...

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Use of U-500 Insulin in the Treatment of Severe Insulin Resistance

Use of U-500 Insulin in the Treatment of Severe Insulin Resistance

... body insulin dose-response curve for insulin ...daily insulin administration to achieve target goals are shown; ie, ...syndromic insulin resistance ...of insulin are required to ...

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Obesity/insulin resistance is associated with endothelial dysfunction  Implications for the syndrome of insulin resistance

Obesity/insulin resistance is associated with endothelial dysfunction Implications for the syndrome of insulin resistance

... Insulin resistance states such as hypertension (8) and non– insulin-dependent diabetes mellitus (NIDDM) (9) have been reported to be associated with both defective insulin-mediated and ...

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