integrin alpha 3 beta 1
Lack of CD151/integrin alpha 3 beta 1 complex is predictive of poor outcome in node-negative lobular breast carcinoma: opposing roles of CD151 in invasive lobular and ductal breast cancers
... Increasing evidence suggests that ILCs and IDCs are biologically different. This is reflected in disparities in morphological and phenotypic characteristics, transcriptomic profiles related particularly to cell-cell and ...
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The role of [alpha]3[beta]1 integrin in cortical development
... α3 integrin (Itga3) gene die during the perinatal period with severe defects in the development of the kidneys, lungs, skin, and cerebral cortex (Kreidberg et ...α3β1 integrin function induces a gliophilic ...
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Involvement of ROS alpha v beta 3 integrin FAK/Pyk2 in the inhibitory effect of melatonin on U251 glioma cell migration and invasion under hypoxia
... Hypoxia, a common and important characteristic of the glioma microenvironment, has been shown to promote glioma cell migration and invasion. To evaluate the effects of melatonin on cell migration under hypoxia, wound ...
11
Alpha-enolase (ENO1) controls alpha v/beta 3 integrin expression and regulates pancreatic cancer adhesion, invasion, and metastasis
... direct integrin/matrix interactions, in a ligand-independent manner, to promote migration ...(especially beta 1 and beta 3) involves the activation of Src, PI3K/AKT, and MEK/ERK1-2 ...
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Overexpression of platelet type 12 lipoxygenase promotes tumor cell survival by enhancing alpha(v)beta(3) and alpha(v)beta(5) integrin expression
... metabolize AA to biologically active metabolites, including hy- droperoxy-eicosatetraenoic acids and HETEs, as well as leukot- rienes (1). 12-LOX is one of at least three LOXs that is expressed as two main ...
10
Exploration of peptide T7 and its derivative as integrin αvβ3-targeted imaging agents
... line Hep2, human hepatocarcinoma cell line HepG2, human non-small cell lung cancer cell line NCI-H157, human lung cancer cell line NCI-H460, and prostate cancer cell line PC3 were maintained in Roswell Park Memorial ...
9
Aberrant integrin expression during epidermal wound healing and in psoriatic epidermis
... hyperproliferative, alpha 2, alpha 3, alpha 6, and beta 1 were no longer confined to the basal layer, as in normal epidermis, but were also found in all the living suprabasal ...
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Vipegitide: a folded peptidomimetic partial antagonist of α2β1 integrin with antiplatelet aggregation activity
... Experiments involving animals and their care were approved by the Committee of Ethics of The Hebrew University and were performed in strict accordance with the Guide for the Care and Use of Laboratory Animals published ...
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Integrin α<sub>v</sub>β<sub>3</sub>-targeted gold nanoshells augment tumor vasculature-specific imaging and therapy
... of 1 cm, consistent temperature elevation to 47 ° C was achieved within 5 minutes at the center of the tumor and was maintained steadily for 10 minutes in the untargeted NS ...
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Nanotetrac targets integrin αvβ3 on tumor cells to disorder cell defense pathways and block angiogenesis
... One of the unique attributes of the tetrac receptor on integrin α v β 3 is that it is linked to the thrombospondin 1 (TSP1; THBS1) gene. Expression of this gene is almost invari- ably suppressed in ...
6
Ligand bridging mediates integrin alpha IIb beta 3 (platelet GPIIB IIIA) dependent homotypic and heterotypic cell cell interactions
... mutant, alpha IIb beta 3 (beta 1-2), indicating that only one of the cells in an interacting pair must be ...activated alpha IIb beta 3 and cells bearing ...
8
A concise review of magnetic resonance molecular imaging of tumor angiogenesis by targeting integrin αvβ3 with magnetic probes
... for integrin α v β ...β 3-positive tumor vessels by an irregular signal intensity decrease in HaCaT-ras-A-5RT3 xenografts, whereas the signal intensity decreased more homogeneously in the control tumors ...
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Integrin Alpha V Beta 3 Matrix Metalloproteinase 2 (MMP 2), Cross Talk
... for 1 hour at 4˚C and then subjected to co immunoprecipitation with anti-αv monoclonal anti- body (1 µg/ml) for overnight shaking at ...of 1× sample buffer ...
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An evaluation of potential reference genes for stability of expression in two salmonid cell lines after infection with either Piscirickettsia salmonis or IPNV
... Intracellular pathogens such as bacteria and viruses modulate key cellular processes which may involve changes in reference gene expression [25,26]. Each pathogen manipulates several cellular transcription path- ways in ...
9
Association between Thrombophilic Genes Polymorphisms and Recurrent Pregnancy Loss Susceptibility in the Iranian Population: a Systematic Review and Meta-Analysis
... Studies have indicated that thrombophilic genes polymorphisms are associated with recurrent pregnancy loss (RPL) in the Iranian population. We aimed to evaluate the precise association between thrombophilic genes ...
12
The relationship between the impaction of Mandibular Third Molar and Guns Ratio
... angles alpha, beta, gonial and Guns ratio on the left and right in each impacted tooth and unerupted groups ...angles alpha, beta and the Guns ratio within the grown and impacted groups ...
5
Functional Analysis of Protein Kinase CK2 of the Human Malaria Parasite Plasmodium falciparum
... PfCK2 ␣ is essential for completion of the erythrocytic asex- ual cycle. We next wanted to determine whether PfCK2 ␣ plays essential functions in parasite survival. To generate a plasmid able to disrupt the PfCK2 ␣ gene, ...
10
Hepatic metabolism of 3 alpha hydroxy 5 beta etianic acid (3 alpha hydroxy 5 beta androstan 17 beta carboxylic acid) in the adult rat
... of 3 alpha-hydroxy-5 beta-etianic acid produced an increase in bile flow ...after beta-glucuronidase hydrolysis, cochromatographed with authentic free 3 alpha-hydroxy-5 ...
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Familial giant cell hepatitis associated with synthesis of 3 beta, 7 alpha dihydroxy and 3 beta,7 alpha, 12 alpha trihydroxy 5 cholenoic acids
... a 3-mo-old boy with cholestatic jaundice were analyzed by ion exchange chromatography and gas chromatography-mass spectrometry ...were 3 beta,7 alpha-dihydroxy-5-cholenoic acid ...
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Human melanoma cells derived from lymphatic metastases use integrin alpha v beta 3 to adhere to lymph node vitronectin
... to integrin alpha v beta ...of alpha v beta 3 on the metastatic cells as compared to the parent ...the alpha v beta 3 receptor plays a role in the process of ...
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